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A New Compact Optical System Proposal and Image Quality Comparison Against Other Affordable Non-mydriatic Fundus Cameras

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Biomedical Engineering Systems and Technologies (BIOSTEC 2018)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1024))

Abstract

Imaging the eye retina is critical to diagnose various pathologies, particularly Diabetic Retinopathy, which is the leading cause of avoidable blindness in the world. The image acquisition through tabletop fundus cameras is the preferred method for retinopathy screening. However, these devices require expertise for operation, limiting its broad application. In this paper, two handheld fundus camera prototypes developed by Fraunhofer AICOS (EyeFundusScope Compact and EyeFundusScope Standard) have their optical capabilities compared, not only between each other but also with another commercially available camera. Field-of-view measurements are performed, as well as a subjective analysis on eye model images acquired with each of prototypes. Besides the comparison between handheld devices in the same experimental setup, conceptual specification on the prototype and optical system for the Compact version are described in order to demonstrate the most relevant issues to be considered when developing a valuable instrument for diabetic retinopathy screening and diagnosis.

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References

  1. Atchison, D., Smith, G.: Optics of the Human Eye, p. 259. Butterworth-Heinemann, Oxford (2000). https://doi.org/10.1016/B978-0-7506-3775-6.50001-8

    Book  Google Scholar 

  2. Benbassat, J., Polak, B.C.P., Javitt, J.C.: Objectives of teaching direct ophthalmoscopy to medical students. Acta Ophthalmol. 90(6), 503–507 (2012). https://doi.org/10.1111/j.1755-3768.2011.02221.x

    Article  Google Scholar 

  3. Born, M., Wolf, E.: Principles of Optics, 7th edn. Cambridge University Press, Cambridge (1999)

    Book  Google Scholar 

  4. Bueno, J.M.: Depolarization effects in the human eye. Vis. Res. 41(21), 2687–2696 (2001). https://doi.org/10.1016/S0042-6989(01)00167-5. http://www.sciencedirect.com/science/article/pii/S0042698901001675

    Article  Google Scholar 

  5. Bunce, C., Wormald, R.: Leading causes of certification for blindness and partial sight in England & Wales. BMC Public Health 6, 58 (2006). https://doi.org/10.1186/1471-2458-6-58

    Article  Google Scholar 

  6. Cheung, N., Mitchell, P., Wong, T.Y.: Diabetic retinopathy. Lancet 376(9735), 124–136 (2010). https://doi.org/10.1016/S0140-6736(09)62124-3

    Article  Google Scholar 

  7. Cronin, T.W., Shashar, N.: The linearly polarized light field in clear, tropical marine waters: spatial and temporal variation of light intensity, degree of polarization and e-vector angle. J. Exp. Biol. 204(14), 2461–2467 (2001). http://jeb.biologists.org/content/204/14/2461

    Google Scholar 

  8. Cunha-Vaz, J.: Characterization and relevance of different diabetic retinopathy phenotypes. Dev. Ophthalmol. 39, 13–30 (2007). https://doi.org/10.1159/000098497

    Article  Google Scholar 

  9. D-EYE S.r.l.: D-EYE Ophthalmoscope. https://www.d-eyecare.com/#vision

  10. Giancardo, L.: Automated fundus images analysis techniques to screen retinal diseases in diabetic patients. Docteur de l ’ université Automated Fundus Images Analysis Techniques to Screen Retinal Diseases in Diabetic Patients (2012)

    Google Scholar 

  11. Hubbard, L.D., et al.: Brightness, contrast, and color balance of digital versus film retinal images in the age-related eye disease study 2. Invest. Ophthalmol. Vis. Sci. 49(8), 3269 (2008). https://doi.org/10.1167/iovs.07-1267

    Article  Google Scholar 

  12. Ophthalmic instruments - Fundus cameras. Standard, International Organization for Standardization, Geneva, CH (2009)

    Google Scholar 

  13. Jenkins, F., White, H.: Fundamentals of Optics. McGraw-Hill, New York (1957). https://books.google.pt/books?id=SAwJAQAAIAAJ

    MATH  Google Scholar 

  14. Jin, K., Lu, H., Su, Z., Cheng, C., Ye, J., Qian, D.: Telemedicine screening of retinal diseases with a handheld portable non-mydriatic fundus camera. BMC Ophthalmol. 17(1), 89 (2017). https://doi.org/10.1186/s12886-017-0484-5

    Article  Google Scholar 

  15. Kauppi, T.: Eye Fundus Image Analysis for Automatic Detection of Diabetic Retinopathy (2010)

    Google Scholar 

  16. van de Kraats, J., Berendschot, T.T., van Norren, D.: The pathways of light measured in fundus reflectometry. Vis. Res. 36(15), 2229–2247 (1996). https://doi.org/10.1016/0042-6989(96)00001-6

    Article  Google Scholar 

  17. Melo, D., Costa, J., Soares, F., Vieira, P.: Optical design of a compact image acquisition device for mobile diabetic retinopathy screening. In: Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIODEVICES, vol. 1, pp. 63–70. INSTICC, SciTePress (2018). https://doi.org/10.5220/0006592200630070

  18. Optomed Oy Ltd.: Optomed Aurora. https://www.optomed.com/optomedaurora

  19. Patton, N., Aslam, T., MacGillivray, T., Pattie, A., Deary, I.J., Dhillon, B.: Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures. J. Anat. 206(4), 319–348 (2005). https://doi.org/10.1111/j.1469-7580.2005.00395.x. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571489/, 15817102[pmid]

    Article  Google Scholar 

  20. Peli, E.: Ophthalmic applications of circular polarizers. J. Am. Optom. Assoc. 57, 298–302 (1986)

    Google Scholar 

  21. Pérez, M.A., Bruce, B.B., Newman, N.J., Biousse, V.: The use of retinal photography in non-ophthalmic settings and its potential for neurology. Neurologist 18(6), 350–355 (2012). https://doi.org/10.1097/NRL.0b013e318272f7d7. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521530/, 23114666[pmid]

    Article  Google Scholar 

  22. Phillips, C.I.: Dilate the pupil and see the fundus. Br. Med. J. (Clin. Res. Ed.) 288(6433), 1779–1780 (1984). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1441835/, 6428541[pmid]

    Article  Google Scholar 

  23. do Prado, R.S., Figueiredo, E.L., Magalhaes, T.V.B.: Retinal detachment in preeclampsia. Arquivos brasileiros de cardiologia 79(2), 183–186 (2002). https://doi.org/10.1590/S0066-782X2002001100011. http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=med4&NEWS=N&AN=12219193

    Article  Google Scholar 

  24. Quellec, G., Bazin, L., Cazuguel, G., Delafoy, I., Cochener, B., Lamard, M.: Suitability of a low-cost, handheld, nonmydriatic retinograph for diabetic retinopathy diagnosis. Transl. Vis. Sci. Technol. 5(2), 16 (2016). https://doi.org/10.1167/tvst.5.2.16

    Article  Google Scholar 

  25. Salz, D.A., Witkin, A.J.: Imaging in diabetic retinopathy. Middle East Afr. J. Ophthalmol. 22(2), 145 (2015)

    Article  Google Scholar 

  26. Shen, B.Y., Mukai, S.: A portable, inexpensive, nonmydriatic fundus camera based on the raspberry pi® computer. J. Ophthalmol. 2017(3), 5 (2017). https://doi.org/10.1155/2017/4526243. http://www.sciencedirect.com/science/article/pii/S0022231399005992

    Article  Google Scholar 

  27. Swedish, T., Roesch, K., Lee, I., Rastogi, K., Bernstein, S., Raskar, R.: EyeSelfie: self directed eye alignment using reciprocal eye box imaging. ACM Trans. Graph. 34(4), 58 (2015)

    Article  Google Scholar 

  28. Tarr, J.M., Kaul, K., Chopra, M., Kohner, E.M., Chibber, R.: Pathophysiology of diabetic retinopathy. ISRN Ophthalmol. 2013, 1–13 (2013). https://doi.org/10.1155/2013/343560

    Article  Google Scholar 

  29. Tocci, M.: How to model the human eye in zemax (2007). http://www.zemax.com/kb/articles/186/1/How-to-Model-the-Human-Eye-in-ZEMAX/Page1.html

  30. Tran, K., Mendel, T.A., Holbrook, K.L., Yates, P.A.: Construction of an inexpensive, hand-held fundus camera through modification of a consumer “point-and-shoot” camera. Invest. Ophthalmol. Vis. Sci. 53(12), 7600–7607 (2012)

    Article  Google Scholar 

  31. Tuchin, V.V.: Polarized light interaction with tissues. J. Biomed. Opt. 21, 1–37 (2016). https://doi.org/10.1117/1.JBO.21.7.071114

    Article  Google Scholar 

  32. Volk Optical Inc.: Volk InView. https://volk.com/index.php/volk-products/ophthalmic-cameras/volk-inview.html

  33. Volk Optical Inc.: Volk Pictor Plus. https://volk.com/index.php/volk-products/ophthalmic-cameras/volk-pictor-plus-digital-ophthalmic-imager.html

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Acknowledgements

We would like to acknowledge the financial support obtained from North Portugal Regional Operational Programme (NORTE 2020), Portugal 2020 and the European Regional Development Fund (ERDF) from European Union through the project Symbiotic technology for societal efficiency gains: Deus ex Machina (DEM), NORTE-01-0145-FEDER-000026.

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Authors and Affiliations

  1. Department of Physics, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Quinta da Torre, 2829-516, Caparica, Portugal

    David Melo & Pedro Vieira

  2. Fraunhofer Portugal AICOS, Rua Alfredo Allen, 455/461, 4200-135, Porto, Portugal

    David Melo, Filipe Soares, Simão Felgueiras & João Gonçalves

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  1. David Melo
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  2. Filipe Soares
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  3. Simão Felgueiras
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  4. João Gonçalves
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  5. Pedro Vieira
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Corresponding author

Correspondence to David Melo .

Editor information

Editors and Affiliations

  1. University of Sao Paulo, São Paulo, Brazil

    Alberto Cliquet Jr.

  2. University of Saskatchewan, Saskatoon, Canada

    Sheldon Wiebe

  3. College of Charleston, Charleston, SC, USA

    Paul Anderson

  4. University of Rome Tor Vergata, Rome, Italy

    Giovanni Saggio

  5. Aberystwyth University, Aberystwyth, UK

    Reyer Zwiggelaar

  6. LIBPhys, New University of Lisbon, Lisbon, Portugal

    Hugo Gamboa

  7. Instituto de Telecomunicações and Instituto Superior Técnico, Lisbon, Portugal

    Ana Fred

  8. Madeira Interactive Technologies Institute, Universidade da Madeira, Funchal, Portugal

    Sergi Bermúdez i Badia

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Melo, D., Soares, F., Felgueiras, S., Gonçalves, J., Vieira, P. (2019). A New Compact Optical System Proposal and Image Quality Comparison Against Other Affordable Non-mydriatic Fundus Cameras. In: Cliquet Jr., A., et al. Biomedical Engineering Systems and Technologies. BIOSTEC 2018. Communications in Computer and Information Science, vol 1024. Springer, Cham. https://doi.org/10.1007/978-3-030-29196-9_2

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  • DOI: https://doi.org/10.1007/978-3-030-29196-9_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29195-2

  • Online ISBN: 978-3-030-29196-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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