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Lower Extremity Ischemia

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Practical Cardiology

Abstract

Lower extremity limb pain is a common complaint among patients, particularly the elderly. The first step is to define the cause of the lower extremity pain and, in reference to the topic at hand, determine whether ischemic arterial vascular disease is the causal factor. Once other common causes of limb pain such as arthritis, low back pain, and musculoskeletal and neurologic causes are eliminated, the workup for ischemic vascular disease should commence. Peripheral arterial disease (PAD) is by far the most common disease manifestation of systemic atherosclerosis in patients, apart from coronary heart disease, and is estimated to occur in up to 15% of persons older than 55 years [1]. Risk factors for PAD are the same as those for coronary heart disease and include increasing age, tobacco use, hypertension, hyperlipidemia, male gender, hyperhomocystinemia, and diabetes. Other less common causes of lower extremity vascular occlusive disease symptoms include Buerger’s disease (primary small-vessel obliterative arteriopathy associated with tobacco use) and systemic arteritides such as Takayasu’s arteritis.

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Gallagher, K.A., Rectenwald, J.E., Froehlich, J.B., Henke, P.K. (2020). Lower Extremity Ischemia. In: Baliga, R., Eagle, K. (eds) Practical Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-030-28328-5_28

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