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The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology: Introduction and Overview

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The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology

Abstract

The International Academy of Cytology (IAC) Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy (FNAB) Cytology reporting system is an initiative of the IAC that seeks to provide a comprehensive, standardized approach to breast FNAB reporting to facilitate reproducible cytopathology reporting and to establish best practice guidelines. The system is evidence-based, supports a structured reporting format and will aid in maximizing the usefulness of the FNAB technique and optimizing communication with the clinical team and the patient.

The use of five categories was chosen to maintain a high negative predictive value of a benign diagnosis and a high positive predictive value of a malignant diagnosis. The categories are Insufficient/Inadequate, Benign, Atypical, Suspicious of Malignancy and Malignant and stratify breast FNAB cytology by the risk of malignancy.

The role of FNAB and the technique of performing FNAB and making direct smears are presented.

The Atlas outlines the definitions for each of the categories and provides key cytological diagnostic criteria, differential diagnoses and photomicrographs for the range of specific diagnoses for each category. The Atlas addresses in detail the problem areas of atypical and suspicious of malignancy, in particular the interpretation of in situ and borderline lesions. A management chapter is included to assist in determining management for each category in a spectrum of clinical scenarios and with a range of medical resources.

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Author information

Authors and Affiliations

  1. University of NSW and University of Notre Dame Medical Schools, St Vincent’s Hospital, Sydney, Australia

    Andrew S. Field

  2. Flinders Medical Centre, Flinders University of South Australia and Clinpath Laboratories, Adelaide, Australia

    Wendy A. Raymond

  3. St. George Hospital, BreastScreen, Sydney, NSW, Australia

    Mary T. Rickard

  4. Sydney Breast Clinic, Sydney, NSW, Australia

    Lauren Arnold

  5. Department of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

    Elena F. Brachtel

  6. Department of Pathology, Faculty of Medicine, Chiangmai University, Chiangmai, Thailand

    Benjaporn Chaiwun

  7. Department of Pathology, Beijing Hospital and National Center of Gerontology, Beijing, China

    Lan Chen

  8. Department of Pathology, Sengkang General Hospital, Singapore, Singapore

    P. Y. Chong

  9. Department of Pathology, University of Trieste, Trieste, Italy

    Luigi Di Bonito

  10. CBLpath Laboratories, Department of Cytopathology, Rye Brook, NY, USA

    Rana S. Hoda

  11. Department of Pathology and Laboratory Medicine University of Wisconsin, Madison, Medical Director, University of Wisconsin State Laboratory of Hygiene (WSLH), Director, Disease Prevention Division, Madison, WI, USA

    Daniel F. I. Kurtycz

  12. Department of Histopathology, Nottingham University Hospitals, Nottingham, UK

    Andrew H. S. Lee

  13. St Vincent’s Hospital, Sydney, The Kinghorn Cancer Centre, Sydney, NSW, Australia

    Elgene Lim

  14. Department of Pathology, University of California San Francisco, San Francisco, CA, USA

    Britt-Marie Ljung

  15. Cytology Unit, Department of Anatomical Pathology, Faculty of Health Science, University of the Witwatersrand and National Health Laboratory Service, Johannesburg, Gauteng, South Africa

    Pamela Michelow

  16. Nippon Koukan Hospital, Keio University School of Medicine, Department of Diagnostic Pathology, Kawasaki, Kanagawa, Japan

    Robert Y. Osamura

  17. Department of Pathology, University Hospital of Trieste, Trieste, Italy

    Maurizio Pinamonti

  18. Akershus University Hospital, Department of Pathology, Lørenskog, Viken, Norway

    Torill Sauer

  19. St Vincent’s Private Hospital and St Vincent’s Clinic, Department of Surgery, Darlinghurst, NSW, Australia

    Davendra Segara

  20. Prince of Wales Hospital, Department of Anatomical and Cellular Pathology, Kowloon, Hong Kong SAR

    Gary M. Tse

  21. Medipath, American Hospital of Paris, Department of Pathology, Paris, France

    Philippe Vielh

  22. Institute of Molecular Pathology and Immunology of Porto University (IPATIMUP), Medical Faculty of Porto University, Porto, Portugal

    Fernando Schmitt

Authors
  1. Andrew S. Field
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  2. Wendy A. Raymond
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  3. Mary T. Rickard
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  4. Lauren Arnold
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  5. Elena F. Brachtel
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  6. Benjaporn Chaiwun
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  7. Lan Chen
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  8. P. Y. Chong
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  9. Luigi Di Bonito
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  10. Rana S. Hoda
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  11. Daniel F. I. Kurtycz
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  12. Andrew H. S. Lee
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  13. Elgene Lim
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  14. Britt-Marie Ljung
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  15. Pamela Michelow
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  16. Robert Y. Osamura
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  17. Maurizio Pinamonti
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  18. Torill Sauer
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  19. Davendra Segara
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  20. Gary M. Tse
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  21. Philippe Vielh
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  22. Fernando Schmitt
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Corresponding author

Correspondence to Andrew S. Field .

Editor information

Editors and Affiliations

  1. University of NSW and University of Notre Dame Medical Schools, St Vincent’s Hospital, Sydney, Australia

    Andrew S. Field

  2. Flinders Medical Centre, Flinders University of South Australia and Clinpath Laboratories, Adelaide, Australia

    Wendy A. Raymond

  3. Institute of Molecular Pathology and Immunology of Porto University (IPATIMUP), Medical Faculty of Porto University, Porto, Portugal

    Fernando Schmitt

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Field, A.S. et al. (2020). The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology: Introduction and Overview. In: Field, A.S., Raymond, W.A., Schmitt, F. (eds) The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology. Springer, Cham. https://doi.org/10.1007/978-3-030-26883-1_1

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  • DOI: https://doi.org/10.1007/978-3-030-26883-1_1

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