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OCT Technique: Past, Present and Future

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OCT and Imaging in Central Nervous System Diseases

Abstract

Optical coherence tomography (OCT) has become the cornerstone technology in clinical and research imaging in the past two and half decades. OCT performs in vivo, real-time, noncontact scanning and provides cross-sectional and volumetric images with a resolution approaching that of histology. The technology has been used in various medical disciplines, but it is still most profoundly used in the field of ophthalmology where it was initially applied. OCT is continuously evolving with newly developed applications. This chapter will describe the basic principles of OCT techniques, its history, current status, major ophthalmic applications, and research that will determine the future of the technology.

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Abbreviations

2D:

Two-dimensional

3D:

Three-dimensional

AO:

Adaptive optics

CCD:

Charge-coupled device

EDI:

Enhanced depth imaging

FD:

Fourier domain

GCC:

Ganglion cell complex

ILM:

Internal limiting membrane

IPL:

Inner plexiform layer

IS:

Inner segment

LC:

Lamina cribrosa

OCT:

Optical coherence tomography

OCTA:

Optical coherence tomography angiography

ONH:

Optic nerve head

OS:

Outer segment

PS:

Polarization sensitive

RGC:

Retinal ganglion cell

RNFL:

Retinal nerve fiber layer

RPE:

Retinal pigment epithelium

SD:

Spectral domain

SS:

Swept source

TD:

Time-domain

Vis-OCT:

Visible light optical coherence tomography

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Authors and Affiliations

  1. Department of Ophthalmology, University of Pittsburgh School of Medicine, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Sciences Research Center, Pittsburgh, PA, USA

    Tigran Kostanyan

  2. Department of Ophthalmology, NYU Langone Health, NewYork, NY, USA

    Maria de los Angeles Ramos-Cadena, Gadi Wollstein & Joel S. Schuman

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  1. Tigran Kostanyan
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  2. Maria de los Angeles Ramos-Cadena
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  3. Gadi Wollstein
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  4. Joel S. Schuman
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Correspondence to Joel S. Schuman .

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Editors and Affiliations

  1. University of Warmia and Mazury, Olsztyn, Poland

    Andrzej Grzybowski

  2. Studio Oculistico d’Azeglio, Bologna, Italy

    Piero Barboni

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Kostanyan, T., de los Angeles Ramos-Cadena, M., Wollstein, G., Schuman, J.S. (2020). OCT Technique: Past, Present and Future. In: Grzybowski, A., Barboni, P. (eds) OCT and Imaging in Central Nervous System Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-26269-3_2

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