Abstract
Genetics is the study of heredity. In this introductory chapter of the book Genetics of Endocrine Diseases and Syndromes, we present the basic terms of genetics and basic physiological and pathogenic molecular processes that are implicated in the wide array of genetically determined diseases. Mutations, chromosomes, polymorphisms, and epigenetic terms are also briefly discussed.
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Abbreviations
- DNA:
-
Deoxyribonucleic acid
- ICR:
-
Imprinting control region
- lncRNA:
-
Long noncoding RNA
- LOH:
-
Loss of heterozygosity
- MEN1:
-
Multiplex endocrine neoplasia type 1
- miRNA:
-
microRNA
- mRNA:
-
Messenger ribonucleic acid
- piRNA:
-
Piwi-interacting RNA
- RNA:
-
Ribonucleic acid
- rRNA:
-
Ribosomal RNA
- siRNA:
-
Small interfering RNA
- SNP:
-
Single-nucleotide polymorphism
- tRNA:
-
Transfer RNA
- UPD:
-
Uniparental disomy
- UTR:
-
Untranslated region
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Acknowledgments
Supported by the Higher Education Institutional Excellence Programme of the Ministry of Human Capacities in Hungary, within the framework of the molecular biology thematic program of the Semmelweis University.
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Perge, P., Igaz, P. (2019). Basic Concepts of Genetics. In: Igaz, P., Patócs, A. (eds) Genetics of Endocrine Diseases and Syndromes. Experientia Supplementum, vol 111. Springer, Cham. https://doi.org/10.1007/978-3-030-25905-1_1
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DOI: https://doi.org/10.1007/978-3-030-25905-1_1
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