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Skin Biopsy with Cutaneous Nerve Fiber Evaluation

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A Case-Based Guide to Neuromuscular Pathology

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Abstract

Skin biopsy with intraepidermal nerve fiber density evaluation has become the gold standard diagnostic test for small fiber neuropathy. The density of cutaneous autonomic fibers, including sudomotor, vasomotor, and pilomotor fibers can also be evaluated on skin biopsy sections. The skin biopsy procedure, skin biopsy specimen processing, and small cutaneous nerve fiber evaluation are reviewed in this chapter.

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Authors and Affiliations

  1. Departments of Neurology and Pathology, Boston University Medical Center, Boston, MA, USA

    Lan Zhou

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  1. Lan Zhou
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Correspondence to Lan Zhou .

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Editors and Affiliations

  1. Departments of Neurology and Pathology, Boston University Medical Center, Boston, MA, USA

    Lan Zhou

  2. Department of Pathology, Neuropathology Section, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Dennis K. Burns

  3. Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Chunyu Cai

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Zhou, L. (2020). Skin Biopsy with Cutaneous Nerve Fiber Evaluation. In: Zhou, L., Burns, D., Cai, C. (eds) A Case-Based Guide to Neuromuscular Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-25682-1_3

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  • DOI: https://doi.org/10.1007/978-3-030-25682-1_3

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