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Arteriovenous Malformation

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Vascular Anomalies

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Abstract

Arteriovenous malformation (AVM) is a fast-flow vascular anomaly characterized by the shunting of blood from the arterial to venous circulation. Patients suffer from deformity, pain, ulceration, and bleeding. Most lesions are somatic caused by mutations in MAP2K1; familial forms also exist [capillary malformation-arteriovenous malformation (CM-AVM), hereditary hemorrhagic telangiectasia (HHT), PTEN-associated vascular anomaly (PTEN-AVA)]. Treatment has included embolization and/or resection. Embolization palliates symptoms and reduces bleeding prior to operative intervention. Resection is rarely curative, and the recurrence rate is high. Medical options are being explored as possible treatment options.

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Author information

Authors and Affiliations

  1. Department of Plastic and Oral Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA

    Arin K. Greene

  2. Department of Radiology, Medical College of Wisconsin, St. Petersburg, FL, USA

    Patricia E. Burrows

Authors
  1. Arin K. Greene
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  2. Patricia E. Burrows
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Corresponding author

Correspondence to Patricia E. Burrows .

Editor information

Editors and Affiliations

  1. Dana-Farber Cancer Institute, Boston Children’s Hospital, Boston, MA, USA

    Cameron C. Trenor III

  2. Dana-Farber Cancer Institute, Boston Children’s Hospital, Boston, MA, USA

    Denise M. Adams

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Greene, A.K., Burrows, P.E. (2020). Arteriovenous Malformation. In: Trenor III, C., Adams, D. (eds) Vascular Anomalies. Springer, Cham. https://doi.org/10.1007/978-3-030-25624-1_11

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  • DOI: https://doi.org/10.1007/978-3-030-25624-1_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-25622-7

  • Online ISBN: 978-3-030-25624-1

  • eBook Packages: MedicineMedicine (R0)

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