Abstract
Structure is a fundamental factor in determining the way that digestible and non-digestible food carbohydrates (mono- and di-saccharides, oligo-saccharides and polysaccharides) influence a range of health outcomes. Much of the influence of carbohydrate structure on health is mediated by its effects on digestive processes throughout the gut. At each region within the gut a hierarchy of carbohydrate-based food structures – monosaccharide, individual polysaccharide, associated polysaccharides, cell walls, plant tissues and food particles – may constrain or enhance digestive processes. The role of carbohydrate structure in health and reformulation for health, through its effects at the gut level, is the focus of this chapter. Emphasis is placed on blood glucose loading, colonic fermentation and distal colonic bulking, because they are at the base of clusters of health outcomes arising from hyperglycaemia, dysbiosis and constipation, respectively. This chapter outlines principles governing choice of carbohydrate ingredients in reformulating for health, based on the role of food structure in function. Precise prescription of formulations is not possible because of the need for empirical testing of products due to the complexity of food component interactions, emergent properties and sensory effects in food products.
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References
Berg, T., Singh, J., Hardacre, A., & Boland, M. J. (2012). The role of cotyledon cell structure during in vitro digestion of starch in navy beans. Carbohydrate Polymers, 87, 1678–1688.
Bhattarai, R. R., Dhital, S., Wu, P., Chen, X. D., & Gidley, M. J. (2017). Digestion of isolated legume cells in a stomach-duodenum model: Three mechanisms limit starch and protein hydrolysis. Food & Function, 8, 2573–2582.
Borneo, R., & Leon, A. E. (2012). Whole grain cereals: Functional components and health benefits. Food & Function, 3, 110–119.
Brownlee, M. (2005). The pathobiology of diabetic complications – a unifying mechanism. Diabetes, 54, 1615–1625.
Capuano, E. (2017). The behavior of dietary fiber in the gastrointestinal tract determines its physiological effect. Critical Reviews in Food Science and Nutrition, 57, 3543–3564.
Champ, M., Langkilde, A. M., Brouns, F., Kettlitz, B., & Collet, Y. L. (2003). Advances in dietary fibre characterisation. 1. Definition of dietary fibre, physiological relevance, health benefits and analytical aspects. Nutrition Research Reviews, 16, 71–82.
Coudray, C., Tressol, J. C., Gueux, E., & Rayssiguier, Y. (2003). Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats. European Journal of Nutrition, 42, 91–98.
Cummings, J. H., & Engineer, A. (2018). Denis Burkitt and the origins of the dietary fibre hypothesis. Nutrition Research Reviews, 31, 1–15.
Dhital, S., & Gidley, M. (2016). Nutritional role of cellulose beyond faecal bulking. Journal of Nutrition & Intermediary Metabolism, 4, 25–25.
Dhital, S., Bhattarai, R. R., Gorham, J., & Gidley, M. J. (2016). Intactness of cell wall structure controls the in vitro digestion of starch in legumes. Food & Function, 7, 1367–1379.
Dikeman, C. L., & Fahey, G. C., Jr. (2006). Viscosity as related to dietary fiber: A review. Critical Reviews in Food Science and Nutrition, 46, 649–663.
Fardet, A. (2010). New hypotheses for the health-protective mechanisms of whole-grain cereals: What is beyond fibre? Nutrition Research Reviews, 23, 65–134.
Fuller, S., Tapsell, L. C., & Beck, E. J. (2018). Creation of a fibre categories database to quantify different dietary fibres. Journal of Food Composition and Analysis, 71, 36–43.
Gelinas, P. (2013). Preventing constipation: A review of the laxative potential of food ingredients. International Journal of Food Science and Technology, 48, 445–467.
Gidley, M. J. (2013). Hydrocolloids in the digestive tract and related health implications. Current Opinion in Colloid and Interface Science, 18, 371–378.
Gill, P. A., van Zelm, M. C., Muir, J. G., & Gibson, P. R. (2018). Short chain fatty acids as potential therapeutic agents in human gastrointestinal and inflammatory disorders. Alimentary Pharmacology & Therapeutics, 48, 15–34.
Govers, M., Gannon, N. J., Dunshea, F. R., Gibson, P. R., & Muir, J. G. (1999). Wheat bran affects the site of fermentation of resistant starch and luminal indexes related to colon cancer risk: A study in pigs. Gut, 45, 840–847.
Grabitske, H., & Slavin, J. (2009). Gastrointestinal effects of low-digestible carbohydrates. Critical Reviews in Food Science and Nutrition, 49, 327–360.
Hamaker, B. R., & Tuncil, Y. E. (2014). A perspective on the complexity of dietary fiber structures and their potential effect on the gut microbiota. Journal of Molecular Biology, 426, 3838–3850.
Hansen, N. W., & Sams, A. (2018). The microbiotic highway to health-new perspective on food structure, gut microbiota, and host inflammation. Nutrients, 10, E1590.
Hardy, K., Brand-Miller, J., Brown, K. D., Thomas, M. G., & Copeland, L. (2015). The importance of dietary carbohydrate in human evolution. Quarterly Review of Biology, 90, 251–268.
Holt, S. H. A., & Miller, J. B. (1994). Particle-size, satiety and the glycemic response. European Journal of Clinical Nutrition, 48, 496–502.
Horowitz, M., O'Donovan, D., Jones, K. L., Feinle, C., Rayner, C. K., & Samsom, M. (2002). Gastric emptying in diabetes: Clinical significance and treatment. Diabetic Medicine, 19, 177–194.
Howlett, J. F., Betteridge, V. A., Champ, M., Craig, S. A. S., Meheust, A., & Jones, J. M. (2010). The definition of dietary fiber - discussions at the Ninth Vahouny Fiber Symposium: Building scientific agreement. Food & Nutrition Research, 54, 5750.
Jandhyala, S. M., Talukdar, R., Subramanyam, C., Vuyyuru, H., Sasikala, M., & Reddy, D. N. (2015). Role of the normal gut microbiota. World Journal of Gastroenterology, 21, 8787–8803.
Kho, Z. Y., & Lal, S. K. (2018). The human gut microbiome - a potential controller of wellness and disease. Frontiers in Microbiology, 9, 1835.
Kim, C. H. (2018). Immune regulation by microbiome metabolites. Immunology, 154, 220–229.
Kim, E., Coelho, D., & Blachier, F. (2013). Review of the association between meat consumption and risk of colorectal cancer. Nutrition Research, 33, 983–994.
Lentle, R. G. (2018). Deconstructing the physical processes of digestion: Reductionist approaches may provide greater understanding. Food & Function, 9, 4069–4084.
Lentle, R. G., & de Loubens, C. (2015). A review of mixing and propulsion of chyme in the small intestine: Fresh insights from new methods. Journal of Comparative Physiology B, 185, 369–387.
Mackie, A., Bajka, B., & Rigby, N. (2016a). Roles for dietary fibre in the upper GI tract: The importance of viscosity. Food Research International, 88, 234–238.
Mackie, A., Rigby, N., Harvey, P., & Bajka, B. (2016b). Increasing dietary oat fibre decreases the permeability of intestinal mucus. Journal of Functional Foods, 26, 418–427.
Mandalari, G., Merali, Z., Ryden, P., Chessa, S., Bisignano, C., Barreca, D., Bellocco, E., Lagana, G., Faulks, R. M., & Waldron, K. W. (2018). Durum wheat particle size affects starch and protein digestion in vitro. European Journal of Nutrition, 57, 319–325.
Marlett, J. A., & Fischer, M. H. (2002). A poorly fermented gel from psyllium seed husk increases excreta moisture and bile acid excretion in rats. Journal of Nutrition, 132, 2638–2643.
Mishra, S., & Monro, J. (2012). Kiwifruit remnants from digestion in vitro have functional attributes of potential importance to health. Food Chemistry, 135, 2188–2194.
Mishra, S., Edwards, H., Hedderley, D., Podd, J., & Monro, J. (2017). Kiwifruit non-sugar components reduce glycaemic response to co-ingested cereal in humans. Nutrients, 9, E1195.
Mishra, S., Monro, J., & Hedderley, D. (2008). Effect of processing on slowly digestible starch and resistant starch in potato. Starch-Starke, 60, 500–507.
Monro, J. A. (2000). Faecal bulking index: A physiological basis for dietary management of bulk in the distal colon. Asia Pacific Journal of Clinical Nutrition, 9, 74–81.
Monro, J. A. (2001). Wheat bran equivalents based on faecal bulking indices for dietary management of faecal bulk. Asia Pacific Journal of Clinical Nutrition, 10, 242–248.
Monro, J. A. (2004). Virtual food components: Functional food effects expressed as food components. European Journal of Clinical Nutrition, 58, 219–230.
Monro, J. A., & Mishra, S. (2010). Digestion-resistant remnants of vegetable vascular and parenchyma tissues differ in their effects in the large bowel of rats. Food Digestion, 1, 47–56.
Monro, J., & Mishra, S. (2009). Nutritional value of potatoes: Digestibility, glycemic index, and glycemic impact. In L. Kaur & J. Singh (Eds.), Advances in potato chemistry and technology. Burlington: Academic Press.
Monro, J., Mishra, S., Redman, C., Somerfield, S., & Ng, J. (2016). Vegetable dietary fibres made with minimal processing improve health-related faecal parameters in a valid rat model. Food & Function, 7, 2645–2654.
Morita, T., Kasaoka, S., Hase, K., & Kiriyama, S. (1999). Psyllium shifts the fermentation site of high-amylose cornstarch toward the distal colon and increases fecal butyrate concentration in rats. Journal of Nutrition, 129, 2081–2087.
Ndeh, D., Rogowski, A., Cartmell, A., Luis, A. S., Basle, A., Gray, J., Venditto, I., Briggs, J., Zhang, X., Labourel, A., Terrapon, N., Buffetto, F., Nepogodiev, S., Xiao, Y., Field, R. A., Zhu, Y., O'Neill, M. A., Urbanowicz, B. R., York, W. S., Davies, G. J., Wade Abbott, D., Ralet, M.-C., Martens, E. C., Henrissat, B., & Harry J. Giilbert. (2017). Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature, 544, 65, 548.
Olausson, E. A., Alpsten, M., Larsson, A., Mattsson, H., Andersson, H., & Attvall, S. (2008). Small particle size of a solid meal increases gastric emptying and late postprandial glycaemic response in diabetic subjects with gastroparesis. Diabetes Research and Clinical Practice, 80, 231–237.
Palit, S., Lunniss, P. J., & Mark Scott, S. (2012). The physiology of human defecation. Digestive Diseases and Sciences, 57, 1445–1464.
Priyadarshini, M., Kotlo, K. U., Dudeja, P. K., & Layden, B. T. (2018). Role of short chain fatty acid receptors in intestinal physiology and pathophysiology. Comprehensive Physiology, 8, 1091–1115.
Ranawana, V., Monro, J. A., Mishra, S., & Henry, C. J. K. (2010). Degree of particle size breakdown during mastication may be a possible cause of interindividual glycemic variability. Nutrition Research, 30, 246–254.
Robertson, J. A., Ryden, P., Botham, R. L., Reading, S., Gibson, G., & Ring, S. G. (2001). Structural properties of diet-derived polysaccharides and their influence on butyrate production during fermentation. Lebensmittel-Wissenschaft Und-Technologie-Food Science and Technology, 34, 567–573.
Sajilata, M. G., Singhal, R. S., & Kulkarni, P. R. (2006). Resistant starch – a review. Comprehensive Reviews in Food Science and Food Safety, 5, 1–17.
Scazzina, F., Siebenhandl-Ehn, S., & Pellegrini, N. (2013). The effect of dietary fibre on reducing the glycaemic index of bread. British Journal of Nutrition, 109, 1163–1174.
Seal, C. J., & Brownlee, I. A. (2015). Whole-grain foods and chronic disease: Evidence from epidemiological and intervention studies. Proceedings of the Nutrition Society, 74, 313–319.
Stephen, A. M., Champ, M. M. J., Cloran, S. J., Fleith, M., van Lieshout, L., Mejborn, H., & Burley, V. J. (2017). Dietary fibre in Europe: Current state of knowledge on definitions, sources, recommendations, intakes and relationships to health. Nutrition Research Reviews, 30, 149–190.
Svihus, B., & Hervik, A. K. (2016). Digestion and metabolic fates of starch, and its relation to major nutrition-related health problems: A review. Starch-Starke, 68, 302–313.
Takahashi, T., & Sakata, T. (2004). Viscous properties of pig cecal contents and the contribution of solid particles to viscosity. Nutrition, 20, 377–382.
Talley, N. J. (2004a). Definitions, epidemiology, and impact of chronic constipation. Reviews in Gastroenterological Disorders, 4(Suppl 2), S3–S10.
Talley, N. J. (2004b). Management of chronic constipation. Reviews in Gastroenterological Disorders, 4, 18–24.
Tan, J., McKenzie, C., Potamitis, M., Thorburn, A. N., Mackay, C. R., & Macia, L. (2014). The role of short-chain fatty acids in health and disease. Advances in Immunology, 121, 91–119.
Trowell, H. (1976). Definition of dietary fiber and hypotheses that it is a protective factor in certain diseases. American Journal of Clinical Nutrition, 29, 417–427.
van Craeyveld, V., Swennen, K., Dornez, E., van de Wiele, T., Marzorati, M., Verstraete, W., Delaedt, Y., Onagbesan, O., Decuypere, E., Buyse, J., de Ketelaere, B., Broekaert, W. F., Delcour, J. A., & Courtin, C. M. (2008). Structurally different wheat-derived arabinoxylooligosaccharides have different prebiotic and fermentation properties in rats. Journal of Nutrition, 138, 2348–2355.
Warren, F. J., Fukuma, N. M., Mikkelsen, D., Flanagan, B. M., Williams, B. A., Lisle, A. T., Cuiv, P. O., Morrison, M., & Gidley, M. J. (2018). Food starch structure impacts gut microbiome composition. mSphere, 3, e00086.
Whistler, R. L., & BeMiller, J. N. (1997). Carbohydrate chemistry for food scientists. St. Paul: Eagan Press.
Zhang, B., Dhital, S., & Gidley, M. J. (2015). Densely packed matrices as rate determining features in starch hydrolysis. Trends in Food Science & Technology, 43, 18–31.
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Monro, J.A. (2019). Digestible and Non-digestible Polysaccharide Roles in Reformulating Foods for Health. In: Raikos, V., Ranawana, V. (eds) Reformulation as a Strategy for Developing Healthier Food Products. Springer, Cham. https://doi.org/10.1007/978-3-030-23621-2_3
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DOI: https://doi.org/10.1007/978-3-030-23621-2_3
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