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Tetralogy of Fallot

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Critical Care of Children with Heart Disease

Abstract

Tetralogy of Fallot (TOF) is a very common congenital heart defect occurring in approximately 15% of patients with congenital heart disease. More recently, genetic anomalies have been attributed to the development of this disease. The underlying pathology, pathophysiology, and surgical correction stem from the commonly known underlying morphologic defects: VSD, right ventricular hypertrophy, overriding aorta, and right ventricular outflow tract obstruction. Surgical correction early in infancy and appropriate postoperative care at all stages are essential to the ability of these children to live normal adult lives. However, even after correction, patients with TOF have significant considerations as they move into later childhood, adolescence, and adulthood.

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Author information

Authors and Affiliations

  1. Pediatrics and Critical Care Medicine, Cardiac Intensive Care Unit, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Yuliya A. Domnina

  2. Pediatrics Resident, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA

    Jason Kerstein

  3. University of Pittsburgh School of Medicine, Pediatric Cardiology, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA

    Jennifer Johnson

  4. University of Pittsburgh School of Medicine, Department of Cardiothoracic Surgery, Division of Cardiac Surgery, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA

    Mahesh S. Sharma

  5. Division of Adolescent and Young Adult Medicine, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Traci M. Kazmerski

  6. Children’s Heart Institute, Memorial Care Miller Children’s and Women’s Hospital Long Beach, Long Beach, CA, USA

    Constantinos Chrysostomou

  7. Chief, Division of Cardiac Critical Care Medicine Executive Director, Telemedicine Co-director, Children’s National Heart Institute Professor of Pediatrics, George Washington University School of Medicine Children’s National Health System, Washington, DC, USA

    Ricardo A. Munoz

Authors
  1. Yuliya A. Domnina
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  2. Jason Kerstein
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  3. Jennifer Johnson
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  4. Mahesh S. Sharma
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  5. Traci M. Kazmerski
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  6. Constantinos Chrysostomou
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  7. Ricardo A. Munoz
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Corresponding author

Correspondence to Yuliya A. Domnina .

Editor information

Editors and Affiliations

  1. Chief, Division of Cardiac Critical Care Medicine Executive Director, Telemedicine Co-director, Children’s National Heart Institute, Professor of Pediatrics, George Washington University School of Medicine, Children’s National Health System, Washington, DC, USA

    Ricardo A. Munoz

  2. Department of Pediatric Cardiothoracic Surgery, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Victor O. Morell

  3. Associate Medical Director, CHCO Heart Institute Head, Pediatric Cardiac Critical Care Program & Inpatient Services Director, Cardiac Intensive Care Unit Children’s Hospital Colorado, Tenured Professor of Pediatrics, Pediatric Cardiology and Intensive Care University of Colorado Denver, School of Medicine, Aurora, CO, USA

    Eduardo M. da Cruz

  4. Department of Pharmacy, Pediatric Critical Care, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Carol G. Vetterly

  5. Department of Pediatric Cardiothoracic Surgery, UPMC – Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Jose Pedro da Silva

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Domnina, Y.A. et al. (2020). Tetralogy of Fallot. In: Munoz, R., Morell, V., da Cruz, E., Vetterly, C., da Silva, J. (eds) Critical Care of Children with Heart Disease . Springer, Cham. https://doi.org/10.1007/978-3-030-21870-6_18

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  • DOI: https://doi.org/10.1007/978-3-030-21870-6_18

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-21869-0

  • Online ISBN: 978-3-030-21870-6

  • eBook Packages: MedicineMedicine (R0)

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