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Progressive Renal Failure with Lymphopenia

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Pediatric Immunology

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References

  1. Ancliff P, Blundell M, Cory G. Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia. Blood. 2006;108(7):2182–9.

    Article  CAS  Google Scholar 

  2. Massaad M, Ramesh N, Geha R. Wiskott-Aldrich syndrome: a comprehensive review. Ann N Y Acad Sci. 2013;1285(1):26–43.

    Article  CAS  Google Scholar 

  3. Sullivan K, Mullen C, Blaese R. A multi-institutional survey of the Wiskott-Aldrich syndrome. J Pediatr. 1994;125(6):876–85.

    Article  CAS  Google Scholar 

  4. Hoshino A, Shimizu M, Matsukura H, Sakaki-Nakatsubo H, Nomura K, Miyawaki TK. Allogeneic bone marrow transplantation appears to ameliorate IgA nephropathy in a patient with X-linked thrombocytopenia. J Clin Immunol. 2014;34(1):53–7.

    Article  CAS  Google Scholar 

  5. Imai K, Nonoyama S, Ochs HD. WASP (Wiskott-Aldrich syndrome protein) gene mutations and phenotype. Curr Opin Allergy Clin Immunol. 2003;3(6):427–36.

    Article  CAS  Google Scholar 

  6. Orange J, Roy-Ghanta S, Mace E. IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function. J Clin Invest. 2011;121(4):1535–48.

    Article  CAS  Google Scholar 

  7. Ozcan E, Notarangelo L, Geha R. Primary immune deficiencies with aberrant IgE production. J Allergy Clin Immunol. 2008;122(6):1054–62.

    Article  CAS  Google Scholar 

  8. Buchbinder D, Nugent D, Fillipovich A. Wiskott-Aldrich syndrome: diagnosis, current management, and emerging treatments. Appl Clin Genet. 2014;7:55–66.

    Article  CAS  Google Scholar 

  9. Albert M, Bittner T, Nonoyama S. X-linked thrombocytopenia (XLT) due to WAS mutations : clinical characteristics, long-term outcome, and treatment options. Blood. 2010;115(16):3231–8.

    Article  CAS  Google Scholar 

  10. Blundell M, Worth A, Bouma G, Thrasher A. The Wiskott-Aldrich syndrome: the actin cytoskeleton and immune cell function. Dis Markers. 2010;29(3–4):157–75.

    Article  CAS  Google Scholar 

  11. Thrasher A, Burns S. WASP: a key immunological multitasker. Nat Rev Immunol. 2010;10(3):182–92.

    Article  CAS  Google Scholar 

  12. Meyer-bahlburg A, Becker-herman S, Humblet-baron S. Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis. Blood. 2015;112(10):4158–70.

    Article  Google Scholar 

  13. Shin C, Kim M-O, Li D. Outcomes following hematopoietic cell transplantation for Wiskott–Aldrich syndrome. Bone Marrow Transplant. 2012;47(11):1428–35.

    Article  CAS  Google Scholar 

  14. Oshima K, Imai K, Albert M, Bittner T, Strauss G, Filipovich A, Morio T, Kapoor N, Dalal J, Schultz K, Casper J, Notarangelo L, Ochs H. Hematopoietic stem cell transplantation for X-linked thrombocytopenia with mutations in the WAS gene. J Clin Immunol. 2015;35(1):15–21.

    Article  Google Scholar 

  15. Abina SH-B, Gaspar H, Blondeau J, Caccavelli L, Charrier S, Buckland K. Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome. JAMA. 2015;31315:1550–63.

    Article  Google Scholar 

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Correspondence to Roshini S. Abraham .

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Alpern, M., Abraham, R.S. (2019). Progressive Renal Failure with Lymphopenia. In: Rezaei, N. (eds) Pediatric Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-21262-9_131

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  • DOI: https://doi.org/10.1007/978-3-030-21262-9_131

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-21261-2

  • Online ISBN: 978-3-030-21262-9

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