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Oral Cancer

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Oral Diagnosis

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Abstract

Because the clinical appearance of oral mucosal lesions is not an adequate indicator of their diagnosis, status or risk level, additional means of assessing these lesions are needed to ensure accurate and early detection, diagnosis, treatment planning, and execution, as well as monitoring. Early diagnosis is the most important determinant of oral cancer outcomes, yet the majority of oral cancers are detected late, when outcomes are poor. This chapter addresses emerging optical imaging modalities for evaluating oral soft tissue conditions such as dysplasia and malignancy. Desirable attributes include: providing clinical decision-making guidance to improve outcomes, ease and speed of use, appropriate cost for the indicated setting, safety (absence of ionizing radiation), patient-friendly probes, and reliability. In this chapter, the principles behind optical diagnostic approaches, their feasibility and applicability for imaging oral tissues, and their potential usefulness as a tool in the diagnosis of oral cancer and potentially premalignant lesions are reviewed.

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Authors and Affiliations

  1. Section of Oral Medicine, Division of Oral Biology & Medicine, UCLA School of Dentistry, Los Angeles, CA, USA

    Diana Messadi

  2. Department of Oral and Maxillofacial Surgery, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA

    Anh D. Le

  3. University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA

    Takako Tanaka

  4. Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA, USA

    Petra Wilder-Smith

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  1. Diana Messadi
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  2. Anh D. Le
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Correspondence to Petra Wilder-Smith .

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Editors and Affiliations

  1. Beckman Laser Institute, University of California, Irvine School of Medicine, Irvine, CA, USA

    Petra Wilder-Smith

  2. Chao Family Comprehensive Cancer Center, University of California, Irvine School of Medicine, Irvine, CA, USA

    Janet Ajdaharian

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Messadi, D., Le, A.D., Tanaka, T., Wilder-Smith, P. (2020). Oral Cancer. In: Wilder-Smith, P., Ajdaharian, J. (eds) Oral Diagnosis. Springer, Cham. https://doi.org/10.1007/978-3-030-19250-1_5

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