Abstract
Iris melanoma is least frequent of all uveal melanomas. Because of anterior location, iris melanoma is diagnosed and treated when relatively small compared to tumors located in ciliary body and choroid. Melanoma located in the peripheral iris may represent anterior extension of a ciliary body tumor, and therefore it is of paramount importance to examine the ciliary body in cases of iris melanoma when all iris margins of the tumors are not visualized. Iris melanoma may be circumscribed or diffuse. Tapioca iris melanoma is a rare variant of diffuse iris melanoma. Slit-lamp examination, gonioscopy, and ultrasound biomicroscopy (UBM) allow staging of the tumor to guide the most appropriate treatment. Iris melanomas are managed by observation, incisional biopsy, excisional biopsy, or radiotherapy depending upon the size, extent, and visual potential. Iris melanomas tend to be less aggressive in comparison to melanomas in other uveal locations.
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Singh, A.D., Damato, B.E. (2019). Iris Melanoma. In: Damato, B., Singh, A. (eds) Clinical Ophthalmic Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-17879-6_10
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