Abstract
Experimental evidence and clinical experience demonstrate that there are multiple mechanisms involved in cellular damage following neurological insult. Laboratory experiments since the 1950s demonstrated that there are benefits of mild hypothermia. Since that time hypothermia has been proposed as a valid clinical modality for several neurologic conditions.
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Suggested Reading
Peterson K, Carson S, Carney N. Hypothermia treatment for traumatic brain injury: a systematic review and meta-analysis. J Neurotrauma. 2008;25:62–71.
Seder DB, Van der Kloot TE. Methods of cooling: practical aspects of therapeutic temperature management. Crit Care Med. 2009;37(7):S211–22.
Varon J, Pilar A. Therapeutic hypothermia: past present, and future. Chest. 2008;133(5):1267–74.
Acknowledgment
The author thanks Ms. Amy Cissell in Anesthesiology and Perioperative Medicine at the OHSU for designing the hypothermia protocol figure.
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Dauber, M.H. (2020). Temperature Management in Neurosurgical Critical Care. In: Brambrink, A., Kirsch, J. (eds) Essentials of Neurosurgical Anesthesia & Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-030-17410-1_91
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DOI: https://doi.org/10.1007/978-3-030-17410-1_91
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