Abstract
Radiation therapy is a standard treatment option for all stages of prostate cancer. Improvements in imaging and radiation delivery technology have facilitated excellent outcomes with extended courses of conventionally fractionated (1.8–2.0 Gy/fraction) radiation therapy and more recently equivalent outcomes with moderately hypofractionated (2.25–4 Gy/fraction) courses. There is strong evidence that even higher dose hypofractionated regimens (6–10 Gy/fraction), or “oligofractionation” delivered using stereotactic ablative body radiosurgery (SAbR; also referred to as stereotactic body radiation therapy, SBRT), may offer additional clinical benefits, with increased likelihood of durable biochemical control, patient convenience, and possible reduction in cost of care. Recent clinical trials have shown excellent outcomes in appropriately selected patients treated with advanced modern techniques and technology. This chapter will discuss the rationale, clinical experience, and techniques for optimal application of SAbR in the management of localized prostate cancer.
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Folkert, M.R., Hannan, R., Desai, N.B., Timmerman, R.D. (2019). SAbR for Primary Prostate Cancer. In: Trifiletti, D., Chao, S., Sahgal, A., Sheehan, J. (eds) Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy. Springer, Cham. https://doi.org/10.1007/978-3-030-16924-4_25
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DOI: https://doi.org/10.1007/978-3-030-16924-4_25
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