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Difficult Bile Duct Stones

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Dilemmas in ERCP
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Abstract

The first step to treating stones occurring in the bile duct is endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic sphincterotomy followed by a balloon or basket extraction. This is successful in extracting common bile duct stones in the majority of cases. However, there are stones that are characterized as difficult bile duct stones. These include very large stones (>15 mm in diameter), stones in a bile duct that is difficult to access (patients with altered anatomy like Roux-en-Y gastrojejunostomy, Billroth II gastrectomy), or impacted stones. When standard techniques fail, other endoscopic techniques must be explored. These techniques involve increasing the diameter of the biliary orifice with a sphincterotomy, balloon dilation, or a combination of both followed by basket or balloon stone removal. In some cases, large stones may still be difficult to remove in which case lithotripsy can be performed either by mechanical means or by laser and electrohydraulic means. Biliary stents can be placed as a bridge to curative therapy, and they also assist in softening and fragmenting of stones.

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References

  1. Lauri A, Horton RC, Davidson BR, Burroughs AK, Dooley JS. Endoscopic extraction of bile duct stones: management related to stone size. Gut. 1993;34(12):1718–21.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Liao WC, Lee CT, Chang CY, Leung JW, Chen JH, Tsai MC, et al. Randomized trial of 1-minute versus 5-minute endoscopic balloon dilation for extraction of bile duct stones. Gastrointest Endosc. 2010;72(6):1154–62.

    Article  PubMed  Google Scholar 

  3. Fujita N, Maguchi H, Komatsu Y, Yasuda I, Hasebe O, Igarashi Y, et al. Endoscopic sphincterotomy and endoscopic papillary balloon dilatation for bile duct stones: a prospective randomized controlled multicenter trial. Gastrointest Endosc. 2003;57(2):151–5.

    Article  PubMed  Google Scholar 

  4. Ochi Y, Mukawa K, Kiyosawa K, Akamatsu T. Comparing the treatment outcomes of endoscopic papillary dilation and endoscopic sphincterotomy for removal of bile duct stones. J Gastroenterol Hepatol. 1999;14(1):90–6.

    Article  CAS  PubMed  Google Scholar 

  5. Disario JA, Freeman ML, Bjorkman DJ, Macmathuna P, Petersen BT, Jaffe PE, et al. Endoscopic balloon dilation compared with sphincterotomy for extraction of bile duct stones. Gastroenterology. 2004;127(5):1291–9.

    Article  Google Scholar 

  6. Arnold JC, Benz C, Martin WR, Adamek HE, Riemann JF. Endoscopic papillary balloon dilation vs. sphincterotomy for removal of common bile duct stones: a prospective randomized pilot study. Endoscopy. 2001;33(7):563–7.

    Article  CAS  PubMed  Google Scholar 

  7. Weinberg BM, Shindy W, Lo S. Endoscopic balloon sphincter dilation (sphincteroplasty) versus sphincterotomy for common bile duct stones. Cochrane Database Syst Rev. 2006;18(4):CD004890.

    Google Scholar 

  8. Bergman JJ, van Berkel AM, Bruno MJ, Fockens P, Rauws EA, Tijssen JG, et al. A randomized trial of endoscopic balloon dilation and endoscopic sphincterotomy for removal of bile duct stones in patients with a prior Billroth II gastrectomy. Gastrointest Endosc. 2001;53(1):19–26.

    Article  CAS  PubMed  Google Scholar 

  9. Heo JH, Kang DH, Jung HJ, et al. Endoscopic sphincterotomy plus large-balloon dilation versus endoscopic sphincterotomy for removal of bile-duct stones. Gastrointest Endosc. 2007;66(4):720–6; quiz 768, 771.

    Article  PubMed  Google Scholar 

  10. Teoh AY, Cheung FK, Hu B, Pan YM, Lai LH, Chiu PW, et al. Randomized trial of endoscopic sphincterotomy with balloon dilation versus endoscopic sphincterotomy alone for removal of bile duct stones. Gastroenterology. 2013;144(2):341–345.e1.

    Article  Google Scholar 

  11. Stefanidis G, Viazis N, Pleskow D, Manolakopoulos S, Theocharis L, Christodoulou C, Kotsikoros N, et al. Large balloon dilation vs. mechanical lithotripsy for the management of large bile duct stones: a prospective randomized study. Am J Gastroenterol. 2011;106(2):278–85.

    Article  CAS  PubMed  Google Scholar 

  12. Horiuchi A, Nakayama Y, Kajiyama M, Kato N, Kamijima T, Graham DY, et al. Biliary stenting in the management of large or multiple common bile duct stones. Gastrointest Endosc. 2010;71(7):1200–1203.e2.

    Article  PubMed  Google Scholar 

  13. Aslan F, Arabul M, Celik M, Alper E, Unsal B. The effect of biliary stenting on difficult common bile duct stones. Prz Gastroenterol. 2014;9(2):109–15.

    PubMed  PubMed Central  Google Scholar 

  14. Chan AC, Ng EK, Chung SC, Lai CW, Lau JY, Sung JJ, et al. Common bile duct stones become smaller after endoscopic biliary stenting. Endoscopy. 1998;30(4):356–9.

    Article  CAS  PubMed  Google Scholar 

  15. Chang WH, Chu CH, Wang TE, Chen MJ, Lin CC. Outcome of simple use of mechanical lithotripsy of difficult common bile duct stones. World J Gastroenterol. 2005;11(4):593–6.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Garg PK, Tandon RK, Ahuja V, Makharia GK, Batra Y. Predictors of unsuccessful mechanical lithotripsy and endoscopic clearance of large bile duct stones. Gastrointest Endosc. 2004;59(6):601–5.

    Article  PubMed  Google Scholar 

  17. Shaw MJ, Mackie RD, Moore JP, Dorsher PJ, Freeman ML, Meier PB, et al. Results of a multicenter trial using a mechanical lithotripter for the treatment of large bile duct stones. Am J Gastroenterol. 1993;88(5):730–3.

    CAS  PubMed  Google Scholar 

  18. Adamek HE, Maier M, Jakobs R, Wessbecher FR, Neuhauser T, Riemann JF. Management of retained bile duct stones: a prospective open trial comparing extracorporeal and intracorporeal lithotripsy. Gastrointest Endosc. 1996;44(1):40–7.

    Article  CAS  PubMed  Google Scholar 

  19. Adamek HE, Schneider AR, Adamek MU, Jakobs R, Buttmann A, Benz C, et al. Treatment of difficult intrahepatic stones by using extracorporeal and intracorporeal lithotripsy techniques: 10 years’ experience in 55 patients. Scand J Gastroenterol. 1999;34(11):1157–61.

    Article  CAS  PubMed  Google Scholar 

  20. Konstantakis C, Triantos C, Theopistos V, Theocharis G, Maroulis I, Diamantopoulou G, Thomopoulos K. Recurrence of choledocholithiasis following endoscopic bile duct clearance: long term results and factors associated with recurrent bile duct stones. World J Gastrointest Endosc. 2017;9(1):26–33.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Tanaka S, Sawayama T, Yoshioka T. Endoscopic papillary balloon dilation and endoscopic sphincterotomy for bile duct stones: long-term outcomes in a prospective randomized controlled trial. Gastrointest Endosc. 2004;59(6):614–8.

    Article  PubMed  Google Scholar 

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Correspondence to Neil Gupta .

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Mahmood, R., Gupta, N. (2019). Difficult Bile Duct Stones. In: Mullady, D. (eds) Dilemmas in ERCP. Springer, Cham. https://doi.org/10.1007/978-3-030-12741-1_4

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  • DOI: https://doi.org/10.1007/978-3-030-12741-1_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-12740-4

  • Online ISBN: 978-3-030-12741-1

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