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Classification and Clinical Features

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Cluster Headache and other Trigeminal Autonomic Cephalgias

Part of the book series: Headache ((HEAD))

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Abstract

Cluster headache (CH) and other trigeminal autonomic cephalgias (TACs) are primary headaches. Their clinical diagnosis depends on the classification system of the International Headache Society (IHS). TACs are a group of relatively uncommon headaches that share the clinical features of head pain, which is usually unilateral and severe, and prominent cranial autonomic features, which are generally ipsilateral to the pain. Autonomic symptoms include ptosis, miosis, conjunctival injection, tearing, facial and frontal sweating, nasal obstruction, rhinorrhea, and increased intraocular pressure. Characteristically, especially in CH, patients have a very restless behavior with great agitation. Duration of attacks and response to indomethacin are the principal characteristics useful to distinguish each form. This group of headaches includes CH, paroxysmal hemicrania (PH), short-lasting unilateral neuralgiform headache attacks (SUN) with its variants, and hemicrania continua (HC).

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References

  1. Headache Classification Committee of the International Headache Society (IHS). The international classification of headache disorders, 3rd edition. Cephalalgia. 2018;38(1):1–211.

    Article  Google Scholar 

  2. Goadsby PJ, Lipton RB. A review of paroxysmal hemicranias, SUNCT syndrome and other short-lasting headaches with autonomic feature, including new cases. Brain. 1997;120(Pt 1):193–209.

    Article  Google Scholar 

  3. Classification and diagnostic criteria for headache disorders. Cranial neuralgias and facial pain. Headache Classification Committee of the International Headache Society. Cephalalgia. 1988;8(Suppl 7):1–96.

    Google Scholar 

  4. Newman LC. Trigeminal autonomic cephalalgias. Continuum (MinneapMinn). 2015;21(4):1041–57.

    Google Scholar 

  5. Gordon N. History of cluster headache. Curr Pain Headache Rep. 2005;9(2):132–4.

    Article  Google Scholar 

  6. Sjaastad O, Dale I. Evidence for a new (?), treatable headache entity. Headache. 1974;14:105–8.

    Article  CAS  Google Scholar 

  7. Sjaastad O, Saunte C, Salvesen R, Fredriksen TA, Seim A, Røe OD, Fostad K, Løbben OP, Zhao JM. Shortlasting unilateral neuralgiform headache attacks with conjunctival injection, tearing, sweating, and rhinorrhea. Cephalalgia. 1989;9:147–56.

    Article  CAS  Google Scholar 

  8. Cohen AS, Matharu MS, Goadsby PJ. Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) or cranial autonomic features (SUNA)—a prospective clinical study of SUNCT and SUNA. Brain. 2006;129:2746–60.

    Article  Google Scholar 

  9. Prakash S, Patel P. Hemicrania continua: clinical review, diagnosis and management. J Pain Res. 2017;10:1493–509.

    Article  Google Scholar 

  10. Leone M, Bussone G. Pathophysiology of trigeminal autonomic cephalalgias. Lancet Neurol. 2009;8:755–64.

    Article  Google Scholar 

  11. Leone M, Mea E, Genco S, Bussone G. Coexistence of TACs and trigeminal neuralgia: pathophysiological conjectures. Headache. 2006;46(10):1565–70.

    Article  Google Scholar 

  12. Láinez MJ, Guillamón E. Cluster headache and other TACs: pathophysiology and neurostimulation options. Headache. 2017;57(2):327–35.

    Article  Google Scholar 

  13. Hoffmann J, May A. Diagnosis, pathophysiology, and management of cluster headache. Lancet Neurol. 2018;17:75–83.

    Article  Google Scholar 

  14. Barloese M, Haddock B, Lund NT, Petersen A, Jensen R. Chronorisk in cluster headache: a tool for individualised therapy? Cephalalgia. 2018;38(14):2058–67.. [Epub ahead of print]

    Article  Google Scholar 

  15. Manzoni GC, Terzano MG, Bono G. Cluster headache—clinical findings in 180 patients. Cephalalgia. 1983;3:21–30.

    Article  CAS  Google Scholar 

  16. Barloese M, Jennum P, Knudsen S. Cluster headache and sleep, is there a connection? A review. Cephalalgia. 2012;32:481–91.

    Article  CAS  Google Scholar 

  17. Manzoni GC, Micieli G, Granella F, Tassorelli C, Zanferrari C, Cavallini A. Cluster headache—course over ten years in 189 patients. Cephalalgia. 1991;11(4):169–74.

    Article  CAS  Google Scholar 

  18. Burish MJ. Cluster headache: history, mechanisms, and most importantly, treatment options. Pract Neurol. 2016:34–6.

    Google Scholar 

  19. Torelli P, Cologno D, Cademartiri C, Manzoni GC. Application of the International Headache Society classification criteria in 652 cluster headache patients. Cephalalgia. 2001;21(2):145–50.

    Article  CAS  Google Scholar 

  20. Manzoni GC, Maffezzoni M, Lambru G, Lana S, Latte L, Torelli P. Late-onset cluster headache: some considerations about 73 cases. Neurol Sci. 2012;33(Suppl 1):S157–9.

    Article  Google Scholar 

  21. Lambru G, Castellini P, Manzoni GC, Torelli P. Mode of occurrence of traumatic head injuries in male patients with cluster headache or migraine: is there a connection with lifestyle? Cephalalgia. 2010;30(12):1502–8.

    Article  Google Scholar 

  22. Favier I, van Vliet JA, Roon KI, Witteveen RJ, Verschuuren JJ, Ferrari MD, Haan J. Trigeminal autonomic cephalgias due to structural lesions: a review of 31 cases. Arch Neurol. 2007;64(1):25–31.

    Article  Google Scholar 

  23. Weng HY, Cohen AS, Schankin C, Goadsby PJ. Phenotypic and treatment outcome data on SUNCT and SUNA, including a randomised placebo-controlled trial. Cephalalgia. 2018;38(9):1554–63.. [Epub ahead of print]

    Article  Google Scholar 

  24. Pareja JA, Álvarez M, Montojo T. SUNCT and SUNA: recognition and treatment. Curr Treat Options Neurol. 2013;15:28–39.

    Article  Google Scholar 

  25. Favoni V, Grimaldi D, Pierangeli G, Cortelli P, Cevoli S. SUNCT/SUNA and neurovascular compression: new cases and critical literature review. Cephalalgia. 2013;33:1337–48.

    Article  Google Scholar 

  26. Bussone G, Leone M, Dalla Volta G, Strada L, Gasparotti R, Di Monda V. Short-lasting unilateral neuralgiform headache attacks with tearing and conjunctival injection: the first “symptomatic” case? Cephalalgia. 1991;11(3):123–7.

    Article  CAS  Google Scholar 

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Correspondence to Sabina Cevoli .

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Cortelli, P., Cevoli, S., Garcia, J., Láinez, M.J.A. (2020). Classification and Clinical Features. In: Leone, M., May, A. (eds) Cluster Headache and other Trigeminal Autonomic Cephalgias. Headache. Springer, Cham. https://doi.org/10.1007/978-3-030-12438-0_3

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  • DOI: https://doi.org/10.1007/978-3-030-12438-0_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-12437-3

  • Online ISBN: 978-3-030-12438-0

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