Skip to main content

Is It Narcolepsy or Depression Making My Patient Sleepy?

  • Chapter
  • First Online:
Comorbid Sleep and Psychiatric Disorders
  • 747 Accesses

Abstract

Hypersomnia is a symptom of disturbed sleep. Depressive disorders most commonly result in insomnia with fatigue and tiredness but not excessive sleepiness. Hypersomnia with depression is considered a feature of atypical depression and is more common in patients with bipolar disorder or the adolescent/young adult. Hypersomnia becomes clinically significant when the fight against sleepiness results in social and occupational dysfunction. The classic disorder of hypersomnia is narcolepsy with or without the emotionally triggered muscular weakness of cataplexy, although insufficient sleep, circadian misalignment, medication side effect, and sleep disorders such as sleep apnea and idiopathic hypersomnia are other reasons for excessive daytime sleepiness. What follows is a case of a man whose college career was interrupted by hypersomnia, leading to treatment of a presumed depression but subsequent diagnosis of narcolepsy, type II without cataplexy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Selected References

  1. Lopez R, Barateau L, Evangelista E, Dauvilliers Y. Depression and hypersomnia: a complex association. Sleep Med Clin. 2017;12(3):395–405.

    Article  PubMed  Google Scholar 

  2. Barateau L, Lopez R, Franchi JA, Dauvilliers Y. Hypersomnolence, Hypersomnia, and Mood Disorders. Curr Psychiatry Rep. 2017;19(2):13. Review.

    Google Scholar 

  3. American Academy of Sleep Medicine. International classification of sleep disorders, 3rd ed. Darien: American Academy of Sleep Medicine, 2014.

    Google Scholar 

  4. Plante DT, Cook JD, Goldstein MR. Objective measures of sleep duration and continuity in major depressive disorder with comorbid hypersomnolence: a primary investigation with contiguous systematic review and metaanalysis. J Sleep Res. 2017;26(3):255–65. Review.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE. Subjective and objective measures of hypersomnolence demonstrate divergent associations with depression among participants in the Wisconsin Sleep Cohort Study. J Clin Sleep Med. 2016;12(4):571–8.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Asaad T, Sabry W, Rabie M, El-Rassas H. Polysomnographic characteristics of bipolar hypomanic patients: comparison with unipolar depressed patients. J Affect Disord. 2016;191:274–9.

    Article  PubMed  Google Scholar 

  7. Chung KF, Yu YM, Yeung WF. Correlates of residual fatigue in patients with major depressive disorder: the role of psychotropic medication. J Affect Disord. 2015;186:192–7.

    Article  PubMed  Google Scholar 

  8. Zamarian L, Högl B, Delazer M, Hingerl K, Gabelia D, Mitterling T, Brandauer E, Frauscher B. Subjective deficits of attention, cognition and depression in patients with narcolepsy. Sleep Med. 2015;16(1):45–51.

    Article  PubMed  Google Scholar 

  9. Fernandez-Mendoza J, Vgontzas AN, Kritikou I, Calhoun SL, Liao D, Bixler EO. Natural history of excessive daytime sleepiness: role of obesity, weight loss, depression, and sleep propensity. Sleep. 2015;38(3):351–60.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Goldstein AN, Walker MP. The role of sleep in emotional brain function. Annu Rev Clin Psychol. 2014;10:679–708. Review.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Busková J, Kemlink D, Ibarburu V, Nevsímalová S, Sonka K. Antidepressants substantially affect basic REM sleep characteristics in narcolepsy-cataplexy patients. Neuro Endocrinol Lett. 2015;36(5):430–3.

    Google Scholar 

  12. Cooper JA, Tucker VL, Papakostas GI. Resolution of sleepiness and fatigue: a comparison of bupropion and selective serotonin reuptake inhibitors in subjects with major depressive disorder achieving remission at doses approved in the European Union. J Psychopharmacol. 2014;28(2):118–24.

    Article  PubMed  Google Scholar 

  13. Seo HJ, Lee BC, Seok JH, Jeon HJ, Paik JW, Kim W, Kwak KP, Han C, Lee KU, Pae CU. An open-label, raterblinded, 8-week trial of bupropion hydrochloride extended-release in patients with major depressive disorder with atypical features. Pharmacopsychiatry. 2013;46(6):221–6.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Philip M. Becker .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Becker, P.M. (2019). Is It Narcolepsy or Depression Making My Patient Sleepy?. In: Khawaja, I., Hurwitz, T. (eds) Comorbid Sleep and Psychiatric Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-11772-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-11772-6_6

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-11771-9

  • Online ISBN: 978-3-030-11772-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics