Abstract
Data obtained from biosurveillance can be used by public health systems to detect and respond to disease outbreaks and save lives. However, existing data is distributed across large geographic areas, and both the quality and type of data vary in space and time. We discuss a framework for analyzing biosurveillance information to minimize detection time and maximize detection accuracy while scaling the analysis over large regions. We propose that strategies used by canonical biological complex systems, which are adapted to diverse environments, provide good models for the design of a robust, adaptive, and scalable biosurveillance system. Drawing from knowledge of the adaptive immune system, and ant colonies, we examine strategies that support the scaling of detection in order to search and respond in large areas with dynamic distributions of data. Based on this research, we discuss a bioinspired approach for a distributed, adaptive, and scalable biosurveillance system.
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References
Althaus, Christian L. “Of mice, macaques and men: scaling of virus dynamics and immune responses.” Frontiers in microbiology 6 (2015): 355.
Althouse, Benjamin M., et al. “Enhancing disease surveillance with novel data streams: challenges and opportunities.” EPJ Data Science 4.1 (2015): 17.
Banavar, Jayanth R., Melanie E. Moses, James H. Brown, John Damuth, Andrea Rinaldo, Richard M. Sibly, and Amos Maritan. “A general basis for quarter-power scaling in animals.” Proceedings of the National Academy of Sciences 107, no. 36 (2010): 15816–15820.
Banerjee, Soumya, and Melanie E. Moses. “Scale invariance of immune system response rates and times: perspectives on immune system architecture and implications for artificial immune systems.” Swarm Intelligence 4, no. 4 (2010): 301–318.
Banerjee, Soumya, Alan S. Perelson, and Melanie Moses. “Modelling the effects of phylogeny and body size on within-host pathogen replication and immune response.” Journal of The Royal Society Interface 14, no. 136 (2017): 20170479.
Banerjee, Soumya, Drew Levin, Melanie Moses, Frederick Koster, and Stephanie Forrest. “The value of inflammatory signals in adaptive immune responses.” In International Conference on Artificial Immune Systems, pp. 1–14. Springer, Berlin, Heidelberg, 2011.
Brace, Amber J., Marc J. Lajeunesse, Daniel R. Ardia, Dana M. Hawley, James S. Adelman, Katherine L. Buchanan, Jeanne M. Fair, Jennifer L. Grindstaff, Kevin D. Matson, and Lynn B. Martin. “Costs of immune responses are related to host body size and lifespan.” Journal of Experimental Zoology Part A: Ecological and Integrative Physiology 327, no. 5 (2017): 254–261.
DePalma Anthony. “Reliving the nightmare of plague, 10 years on”. The New York Times, Health, January 7, 2013. URL: https://www.nytimes.com/2013/01/08/health/when-the-plague-came-to-new-york.html. Accessed on 3/26/2018. A version of this article appears in print on January 8, 2013, on Page D5 of the New York edition with the headline: Reliving Nightmare Of Plague, 10 Years On.
Donaldson-Matasci, Matina C., Carl T. Bergstrom, and Michael Lachmann. “The fitness value of information.” Oikos 119, no. 2 (2010): 219–230.
Dorigo Marco, Gambardella L, Birattari M, Martinoli A, Poli R, et al.. (2006) Ant Colony Optimization and Swarm Intelligence: 5th International Workshop, ANTS 2006, Brussels, Belgium, September 4–7, 2006, Proceedings: Springer.
Ely, Kenneth H., Tres Cookenham, Alan D. Roberts, and David L. Woodland. “Memory T cell populations in the lung airways are maintained by continual recruitment.” The Journal of Immunology 176, no. 1 (2006): 537–543.
Flanagan, Tatiana P., Noa M. Pinter-Wollman, Melanie E. Moses, and Deborah M. Gordon. “Fast and flexible: Argentine ants recruit from nearby trails.” PloS one 8, no. 8 (2013): e70888.
Foo, S. Y., and S. Phipps. “Regulation of inducible BALT formation and contribution to immunity and pathology.” Mucosal immunology 3, no. 6 (2010): 537.
Fricke, G. Matthew, Kenneth A. Letendre, Melanie E. Moses, and Judy L. Cannon. “Persistence and adaptation in immunity: T cells balance the extent and thoroughness of search.” PLoS computational biology 12, no. 3 (2016): e1004818.
Gajewski, Kimberly N., Amy E. Peterson, Rohit A. Chitale, Julie A. Pavlin, Kevin L. Russell, and Jean-Paul Chretien. “A review of evaluations of electronic event-based biosurveillance systems.” PloS one 9, no. 10 (2014): e111222.
Gordon, Deborah M. Ant encounters: interaction networks and colony behavior. Princeton University Press, 2010.
Gordon, Deborah M. “The evolution of the algorithms for collective behavior.” Cell systems 3, no. 6 (2016): 514–520.
Hecker, Joshua P., and Melanie E. Moses. “Beyond pheromones: evolving error-tolerant, flexible, and scalable ant-inspired robot swarms.” Swarm Intelligence 9, no. 1 (2015): 43–70.
Jiang, Xiaodong, Rachael A. Clark, Luzheng Liu, Amy J. Wagers, Robert C. Fuhlbrigge, and Thomas S. Kupper. “Skin infection generates non-migratory memory CD8+ T RM cells providing global skin immunity.” Nature 483, no. 7388 (2012): 227.
Kleinberg, Jon. “The small-world phenomenon and decentralized search.” SiAM News 37, no. 3 (2004): 1–2.
Lanan, Michele. “Spatiotemporal resource distribution and foraging strategies of ants (Hymenoptera: Formicidae).” Myrmecological news/Osterreichische Gesellschaft fur Entomofaunistik 20 (2014): 53.
Letendre, Kenneth, and Melanie E. Moses. “Synergy in ant foraging strategies: memory and communication alone and in combination.” In Proceedings of the 15th annual conference on Genetic and evolutionary computation, pp. 41–48. ACM, 2013.
Levin, Drew, Joshua P. Hecker, Melanie E. Moses, Stephanie Forrest, G. Matthew Fricke, Sarah R. Black, Judy L. Cannon et al. “Volatility and spatial distribution of resources determine ant foraging strategies.” In Proceedings of the European Conference on Artificial Life (ECAL). (2015).
Levin, Drew, Stephanie Forrest, Soumya Banerjee, Candice Clay, Judy Cannon, Melanie Moses, and Frederick Koster. “A spatial model of the efficiency of T cell search in the influenza-infected lung.” Journal of theoretical biology 398 (2016): 52–63.
Levin, Drew, Melanie E. Moses, Tatiana P. Flanagan, Stephanie Forrest, and Patrick D. Finley. “Negative selection based anomaly detector for multimodal health data.” IEEE Symposium Series on Computational Intelligence (SSCI) (2017).
Lu, Qi, Joshua P. Hecker, and Melanie E. Moses. “Multiple-place swarm foraging with dynamic depots.” Autonomous Robots (2018): 1–18.
Marzen, Sarah E., and Simon DeDeo. “The evolution of lossy compression.” Journal of The Royal Society Interface 14, no. 130 (2017): 20170166.
Moses, Melanie, and Soumya Banerjee. “Biologically inspired design principles for scalable, robust, adaptive, decentralized search and automated response (radar).” In Artificial Life (ALIFE), 2011 IEEE Symposium on, pp. 30–37. IEEE, 2011.
Moses, Melanie, Tatiana Flanagan, Kenneth Letendre, and Matthew Fricke. “Ant colonies as a model of human computation.” In Handbook of human computation, pp. 25–37. Springer, New York, NY, 2013.
Mrass, Paulus, Sreenivasa Rao Oruganti, G. Matthew Fricke, Justyna Tafoya, Janie R. Byrum, Lihua Yang, Samantha L. Hamilton, Mark J. Miller, Melanie E. Moses, and Judy L. Cannon. “ROCK regulates the intermittent mode of interstitial T cell migration in inflamed lungs.” Nature communications 8, no. 1 (2017): 1010.
Nolz, Jeffrey C., Gabriel R. Starbeck-Miller, and John T. Harty. “Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions.” Immunotherapy 3, no. 10 (2011): 1223–1233.
Omilusik, Kyla D., and Ananda W. Goldrath. “The origins of memory T cells.” Nature 552, no. 7685 (2017): 337–339.
Perelson, Alan S., and Frederik W. Wiegel. “Scaling aspects of lymphocyte trafficking.” Journal of theoretical biology 257, no. 1 (2009): 9–16.
Prabhakar, Balaji, Katherine N. Dektar, and Deborah M. Gordon. “The regulation of ant colony foraging activity without spatial information.” PLoS computational biology 8, no. 8 (2012): e1002670.
Rosato, Pamela C., Lalit K. Beura, and David Masopust. “Tissue resident memory T cells and viral immunity.” Current opinion in virology 22 (2017): 44–50.
von Boehmer, Harold. “Developmental biology of T cells in T cell-receptor transgenic mice.” Annual review of immunology, no. 1 (1990): 531–556.
West, Geoffrey B., James H. Brown, and Brian J. Enquist. “A general model for the origin of allometric scaling laws in biology.” Science 276, no. 5309 (1997): 122–126.
Wiegel, Frederik W., and Alan S. Perelson. “Some scaling principles for the immune system.” Immunology and cell biology 82, no. 2 (2004): 127.
Wong, Michael Thomas, David Eng Hui Ong, Frances Sheau Huei Lim, Karen Wei Weng Teng, Naomi McGovern, Sriram Narayanan, Wen Qi Ho et al. “A high-dimensional atlas of human T cell diversity reveals tissue-specific trafficking and cytokine signatures.” Immunity 45, no. 2 (2016): 442–456.
Valentine, Paul. “Bubonic Plague Feared in Death Of Girl in S.C.”. The Washington Post, August 4th, 1983. URL: http://www.washingtonpost.com Accessed on 3/6/2018.
Acknowledgments
We gratefully acknowledge funding from a Sandia National Laboratories Academic Alliance LDRD Award. TPF and MEM also acknowledge funding from the McDonnell Foundation Complex Systems Scholar Award. We also thank Judy Cannon for her insightful guidance on immune system memory cells, Stephanie Forrest for insightful discussions about negative selection and its relevance to biosurveillance, and Louise Maffitt for helpful editing suggestions.
Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration under contract DE-NA0003525. The views expressed in the article do not necessarily represent the views of the U.S. Department of Energy or the United States Government.
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Flanagan, T., Beyeler, W., Levin, D., Finley, P., Moses, M. (2019). Movement and Spatial Specificity Support Scaling in Ant Colonies and Immune Systems: Application to National Biosurveillance. In: Georgiev, G., Smart, J., Flores Martinez, C., Price, M. (eds) Evolution, Development and Complexity. Springer Proceedings in Complexity. Springer, Cham. https://doi.org/10.1007/978-3-030-00075-2_15
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DOI: https://doi.org/10.1007/978-3-030-00075-2_15
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