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Emerging Energies for Focal Ablation of Prostate Cancer

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Technical Aspects of Focal Therapy in Localized Prostate Cancer

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Abstract

Four energy modalities are routinely used for focal therapy (FT) in expert centers: cryotherapy, high-intensity focused ultrasound, vascular-targeted photodynamic therapy, and brachytherapy. In this section, we review the emerging FT energies that are suitable for use in the treatment of localized prostate cancer. Irreversible electroporation is a nonthermal energy that is effective in destroying the cancer cells, with the advantage of sparing surrounding tissue such as blood vessels and neurons, hopefully leading to better functional preservation.

Interstitial microwave thermal therapy, which is a modality based on electromagnetic waves, is an experimental prostate cancer treatment aiming at curing disease while causing lower morbidity than radical therapy causes. We also discuss the potential use of radiofrequency interstitial tumor ablation in the focal treatment of localized prostate cancer.

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Authors and Affiliations

  1. Department of Urology, Institut Montsouris, Paris-Descartes University, 42 bd Jourdan, Paris, 75014, France

    Y. Ahallal & Eric Barret MD

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  1. Y. Ahallal
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  2. Eric Barret MD
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Correspondence to Eric Barret MD .

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Editors and Affiliations

  1. Department of Urology, Institut Montsouris, Paris-Descartes University, Paris, France

    Eric Barret

  2. Department of Urology, Hôpital Pasteur 2 – Centre Hospitalier Universitaire de Nice, Antipolis, France

    Matthieu Durand

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Ahallal, Y., Barret, E. (2015). Emerging Energies for Focal Ablation of Prostate Cancer. In: Barret, E., Durand, M. (eds) Technical Aspects of Focal Therapy in Localized Prostate Cancer. Springer, Paris. https://doi.org/10.1007/978-2-8178-0484-2_16

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  • DOI: https://doi.org/10.1007/978-2-8178-0484-2_16

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