Brief History-Evolution of the Concept
Ottman et al. (1995) first described a large pedigree in which 6 out of 10 affected members with idiopathic focal epilepsy reported prominent auditory features at the onset of partial seizures. Since then, this condition has been reported by many other investigators under the eponyms of autosomal dominant partial epilepsy with auditory features (ADPEAF) or autosomal dominant lateral temporal epilepsy (ADLTE). The latter term is more commonly used because the clinical spectrum may include, besides characteristic auditory symptoms, aphasic seizures or other auras (such as complex visual or vertiginous) that point to a lateral temporal cortex onset.
Classification
ADLTE is classified among autosomal dominant focal epilepsies, a newly recognized chapter of epileptology. ADLTE has been included in the recently developed proposal of the task force for classification of the International League Against Epilepsy under the heading of “familial temporal...
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Abbreviations
- ADLTE:
-
Autosomal dominant lateral temporal epilepsy
- ADPEAF:
-
Autosomal dominant partial epilepsy with auditory features
- DTI:
-
Diffusion tensor imaging
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Nobile, C., Pasini, E., Michelucci, R. (2010). Familial Lateral Temporal Lobe Epilepsy. In: Panayiotopoulos, C.P. (eds) Atlas of Epilepsies. Springer, London. https://doi.org/10.1007/978-1-84882-128-6_168
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DOI: https://doi.org/10.1007/978-1-84882-128-6_168
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