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The Complement System

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1100))

Abstract

Studies in Complement swiftly progressed over the years to yield knowledge that paved the way to the current boom in the interest in Innate Immunity. Complement research generated novel therapeutics that successfully underwent clinical trials, demonstrating that this filed is among the most advanced in biomedical research. Today, we have a novel appreciation of the Complement System that comprises more than 50 fluid and membrane-associated proteins and functions to secure antimicrobial immunity, efficient removal of soluble immune complexes, and tissue regeneration to ensure homeostasis.

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Authors and Affiliations

  1. Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Harvard University, Boston, MA, USA

    Mihaela Gadjeva

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  1. Mihaela Gadjeva
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Editors and Affiliations

  1. Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard University Harvard Medical School, Boston, Massachusetts, USA

    Mihaela Gadjeva

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Gadjeva, M. (2014). Overview. In: Gadjeva, M. (eds) The Complement System. Methods in Molecular Biology, vol 1100. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-724-2_1

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  • DOI: https://doi.org/10.1007/978-1-62703-724-2_1

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-723-5

  • Online ISBN: 978-1-62703-724-2

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