Abstract
Imaging is an essential part of establishing a confident diagnosis in the setting of suspected idiopathic pulmonary fibrosis (IPF), and usual interstitial pneumonia (UIP) represents the imaging and histopathologic correlate of IPF. Although chest radiographs often show abnormalities in patients with UIP, the findings are typically nonspecific. High-resolution computed tomography (HRCT) allows for accurate characterization of many types of pulmonary fibrosis and can be used to establish a confident diagnosis of UIP. When a confident diagnosis of UIP can be made on HRCT, the high accuracy of a high-confidence diagnosis obviates the need to perform a surgical lung biopsy. However, due to significant overlap in the imaging appearance of UIP with other causes of pulmonary fibrosis, caution is necessary in making a diagnosis of IPF when low-confidence patterns of pulmonary fibrosis are present.
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Chung, J.H., Kanne, J.P. (2014). Imaging of Idiopathic Pulmonary Fibrosis. In: Meyer, K., Nathan, S. (eds) Idiopathic Pulmonary Fibrosis. Respiratory Medicine, vol 9. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-682-5_4
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