Skip to main content

Non-pharmacologic Treatment of Pediatric Hypertension

  • Chapter
  • First Online:
Pediatric Hypertension

Abstract

The initial approach to management of primary mild to moderate hypertension in children and adolescents is implementation of changes in lifestyle. Lifestyle intervention may also be quite important as an adjunct to pharmacologic treatment in both primary and secondary forms of hypertension. In that setting, appropriate changes in diet, physical activity, and weight management may allow the use of a lower dose of pharmacologic treatment.

It should not be surprising that lifestyle change is an important therapeutic approach because it is well recognized that hypertension results from a variety of causes, including genetics, obesity, and other environmental and dietary factors. Thus, intervening with changes in diet, increased physical activity, and weight management can disrupt those causal pathways.

In this chapter, we will explore the various non-pharmacologic approaches that have been shown to be effective in blood pressure reduction in children and adolescents. We will focus on dietary interventions, physical activity interventions, weight management, which is quite important for children and adolescents who are overweight or obese, and other interventions, such as stress reduction.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 229.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Kotsis V, Papakatsika S, Stabouli S. The role of obesity, salt and exercise on blood pressure in children and adolescents. Expert Rev Cardiovasc Ther. 2011;9:753–61.

    Article  PubMed  Google Scholar 

  2. He FJ, MacGregor GA. Reducing population salt intake worldwide: from evidence to implementation. Prog Cardiovasc Dis. 2010;52:363–82.

    Article  PubMed  CAS  Google Scholar 

  3. Sugiyama T, Xie D, Graham-Maar RD, Inoue K, Kobayashi Y, Stettler N. Dietary and lifestyle factors associated with blood pressure among US adolescents. J Adolesc Health. 2007;40:166–72.

    Article  PubMed  Google Scholar 

  4. Falkner B, Kushner H, Khalsa DK, Canessa M, Katz S. Sodium sensitivity of children, growth and family history of hypertension in young blacks. J Hypertens. 1986;4:S381–3.

    CAS  Google Scholar 

  5. Yang Q, Zhang Z, Kuklina EV, Fang J, Ayala C, Hong Y, Loustalot F, Dai S, Gunn JP, Tian N, Cogswell ME, Merritt R. Sodium intake and blood pressure among US children and adolescents. Pediatrics. 2012;130:611–9.

    Article  PubMed  Google Scholar 

  6. Chen W, Srinivasan SR, Elkasabany A, Berenson GS. Cardiovascular risk factor clustering features of insulin resistance syndrome in a biracial (black-white) population of children, adolescents, and young adults. The Bogalusa Heart study. Am J Epidemiol. 1999;150:667–74.

    Article  PubMed  CAS  Google Scholar 

  7. Kanai H, Matsuzawa Y, Tokunaga K. Hypertension in obese children: fasting serum insulin levels are closely correlated with blood pressure. Int J Obes. 1990;14:1047–56.

    PubMed  CAS  Google Scholar 

  8. Finta KM, Rocchini AP, Moorehead C, Key J, Katch V. Urine sodium excretion in response to an oral glucose tolerance test in obese and non-obese adolescents. Pediatrics. 1992;90:442–6.

    PubMed  CAS  Google Scholar 

  9. Csabi G, Molna D, Hartmann G. Urinary sodium excretion: association with hyperinsulinemia, hypertension and sympathetic nervous system activity in obese and control children. Eur J Pediatr. 1996;155: 895–7.

    Article  PubMed  CAS  Google Scholar 

  10. Mattes RD, Donnelly D. Relative contributions of dietary sodium sources. J Am Coll Nutr. 1991;10: 383–93.

    PubMed  CAS  Google Scholar 

  11. He FJ, MacGregor GA. Importance of salt in determining blood pressure in children: meta-analysis of controlled trials. Hypertension. 2006;48:861–9.

    Article  PubMed  CAS  Google Scholar 

  12. Centers for Disease Control and Prevention. Usual sodium intakes compared with current dietary guidelines – United States, 2005–2008. MMWR Morb Mortal Wkly Rep. 2011;60:1413–7.

    Google Scholar 

  13. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114:555–76.

    Google Scholar 

  14. Hazebroek A, Hofman A. Sodium content of breast milk in the first six months after delivery. Acta Paediatr. 1983;72:459–60.

    Article  CAS  Google Scholar 

  15. Martin RM, Gunnell D, Smith GD. Breastfeeding in infancy and blood pressure in later life: systematic review and meta-analysis. Am J Epidemiol. 2005;161:15–26.

    Article  PubMed  Google Scholar 

  16. Demmers TA, Jones PJ, Wang Y, Krug S, Creutzinger V, Heubi JE. Effects of early cholesterol intake on cholesterol biosynthesis and plasma lipids among infants until 18 months of age. Pediatrics. 2005;115:1594–601.

    Article  PubMed  Google Scholar 

  17. Parikh NI, Hwang S-J, Ingelsson E, Benjamin EJ, Fox CS, Vasan RS, Murabito JM. Breastfeeding in infancy and adult cardiovascular disease risk factors. Am J Med. 2009;122:656–63.

    Article  PubMed  Google Scholar 

  18. Davis IJ, Grim C, Dwyer K, Nicholson L, Dwyer J. The effects of calcium supplementation on ambulatory blood pressure in African-American adolescents. J Natl Med Assoc. 1996;88:774–8.

    PubMed  CAS  Google Scholar 

  19. Gillman MW, Hood MY, Moore LL, Nguyen US, Singer MR, Andon MB. Effect of calcium supplementation on blood pressure in children. J Pediatr. 1995;127:186–92.

    Article  PubMed  CAS  Google Scholar 

  20. Dwyer JH, Dwyer KM, Scribner RA, Sun P, Li L, Nicholson LM. Dietary calcium, calcium supplementation and blood pressure in African American adolescents. Am J Clin Nutr. 1998;68:648–55.

    PubMed  CAS  Google Scholar 

  21. Sinaiko AR, Gomez-Marin O, Prineas RJ. Effect of low sodium diet or potassium supplementation on adolescent blood pressure. Hypertension. 1993;21: 989–94.

    Article  PubMed  CAS  Google Scholar 

  22. Lasaridis AN. Increased natriuretic ability and hypotensive effect during short-term high calcium intake in essential hypertension. Nephron. 1989;51:517–23.

    Article  PubMed  CAS  Google Scholar 

  23. Staessen J, Bulpitt C, Fagard R, Joossens JV, Lijnen P, Amery A. Four urinary cations and blood pressure. A population study in two Belgian towns. Am J Epidemiol. 1983;117:676–87.

    PubMed  CAS  Google Scholar 

  24. Knuiman JT, Hautvast JG, Zwiauer KF. Blood pressure and excretion of sodium, potassium, calcium and magnesium in 8 to 9-year old boys from 19 European centers. Eur J Clin Nutr. 1988;42:847–55.

    PubMed  CAS  Google Scholar 

  25. Simons-Morton DG, Obarzanek E. Diet and blood pressure in children and adolescents. Pediatr Nephrol. 1997;11:244–9.

    Article  PubMed  CAS  Google Scholar 

  26. Falkner B, Sheriff K, Michel S, Kushner H. Dietary nutrients and blood pressure in urban minority adolescents at risk for hypertension. Arch Pediatr Adolesc Med. 2000;154:918–22.

    PubMed  CAS  Google Scholar 

  27. Simons-Morton DG, Hunsberger SA, Van Horn L. Nutrient intake and blood pressure in the Dietary Intervention Study in Children. Hypertension. 1997;29:930–6.

    Article  PubMed  CAS  Google Scholar 

  28. Stern B, Heyden S, Miller D, Latham G, Glimas A, Pilkington K. Intervention study in high school students with elevated blood pressures. Dietary experiment with polyunsaturated fatty acids. Nutr Metab. 1980;24:137–47.

    Article  PubMed  CAS  Google Scholar 

  29. Goldberg RJ, Ellison RC, Hosmer DW. Effects of alterations in fatty acid intake on the blood pressure of adolescents: the Exeter-Andover Project. Am J Clin Nutr. 1992;56:71–6.

    PubMed  CAS  Google Scholar 

  30. Jenner DA, English DR, Vandongen R. Diet and blood pressure in 9-year old children. Am J Clin Nutr. 1988;47:1052–9.

    PubMed  CAS  Google Scholar 

  31. Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Vogt TM, Cutler JA, Windhauser MM, Lin PH, Karanja N. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med. 1997;336:1117–24.

    Article  PubMed  CAS  Google Scholar 

  32. Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, Obarzanek E, Conlin PR, Miller 3rd ER, Simons-Morton DG, Karanja N, Lin PH, DASH-Sodium Collaborative Research Group. Effect on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med. 2001;344:3–10.

    Article  PubMed  CAS  Google Scholar 

  33. Moore LL, Singer MR, Bradlee ML, Djoussé L, Proctor MH, Cupples LA, Ellison RC. Intake of fruits, vegetables, and dairy products in early childhood and subsequent blood pressure change. Epidemiology. 2005;16:4–11.

    Article  PubMed  Google Scholar 

  34. Couch SC, Saelens BE, Levin L, Dart K, Falciglia G, Daniels SR. The efficacy of a clinic-based behavioral nutrition intervention emphasizing a DASH-type diet for adolescents with elevated blood pressure. J Pediatr. 2008;152:494–501.

    Article  PubMed  Google Scholar 

  35. Damasceno MM, de Araújo MF, de Freitas RW, de Almeida PC, Zanetti ML. The association between blood pressure in adolescents and the consumption of fruits, vegetables and fruit juice–an exploratory study. J Clin Nurs. 2011;122:2521–8.

    Google Scholar 

  36. Günther AL, Liese AD, Bell RA, Dabelea D, Lawrence JM, Rodriguez BL, Standiford DA, Mayer-Davis EJ. Association between the dietary approaches to hypertension diet and hypertension in youth with diabetes mellitus. Hypertension. 2009;53:6–12.

    Article  PubMed  Google Scholar 

  37. Sallis JF, Haskell WL, Wood PD, Fortmann SP, Vranizan KM. Vigorous physical activity and cardiovascular risk factors in young adults. J Chronic Dis. 1986;39:115–20.

    Article  PubMed  CAS  Google Scholar 

  38. Blair SN, Goodyear NN, Gibbons LW, Cooper KH. Physical fitness and incidence of hypertension in healthy normotensive men and women. JAMA. 1984;252:487–90.

    Article  PubMed  CAS  Google Scholar 

  39. Gidding SS, Barton BA, Dorgan JA, Kimm SY, Kwiterovich PO, Lasser NL, Robson AM, Stevens VJ, Van Horn L, Simons-Morton DG. Higher self-reported physical activity is associated with lower systolic blood pressure: the Dietary Intervention Study in Childhood (DISC). Pediatrics. 2006;118: 2388–93.

    Article  PubMed  Google Scholar 

  40. Lurbe E, Cifkova R, Cruickshank JK, Dillon MJ, Ferreira I, Invitti C, Kuznetsova T, Laurent S, Mancia G, Morales-Olivas F, Rascher W, Redon J, Schaefer F, Seeman T, Stergiou G, Wühl E, Zanchetti A. Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension. J Hypertens. 2009;27: 1719–42.

    Article  PubMed  CAS  Google Scholar 

  41. Whelton SP, Chin A, Xin X, He J. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Ann Intern Med. 2002;136:493–503.

    Article  PubMed  Google Scholar 

  42. Cornelissen VA, Fagard RH. Effect of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors. Hypertension. 2005;46:667–75.

    Article  PubMed  CAS  Google Scholar 

  43. Cornelissen VA, Fagard RH. Effect of resistance training on resting BP: a meta-analysis of randomized controlled trials. J Hypertens. 2005;23:251–9.

    Article  PubMed  CAS  Google Scholar 

  44. Pescatello LS, Franklin BA, Fagard R, Farquhar WB, Kelley GA, Ray CA, American College of Sports Medicine. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc. 2004;36:533–53.

    Article  PubMed  Google Scholar 

  45. Marcus BH, Williams DM, Dubbert PM, Sallis JF, King AC, Yancey AK, Franklin BA, Buchner D, Daniels SR, Claytor RP, American Heart Association Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity); American Heart Association Council on Cardiovascular Disease in the Young; Interdisciplinary Working Group on Quality of Care and Outcomes Research. Physical activity intervention studies: what we know and what we need to know: a scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity); Council on Cardiovascular Disease in the Young; and the Interdisciplinary Working Group on Quality of Care and Outcomes Research. Circulation. 2006;114: 2739–52.

    Article  PubMed  Google Scholar 

  46. Kelley GA, Kelley KS, Tran ZV. The effects of exercise on resting blood pressure in children and adolescents: a meta-analysis of randomized controlled trials. Prev Cardiol. 2003;6:8–16.

    Article  PubMed  Google Scholar 

  47. Strong WV, Malina RM, Blimkie CJ, Daniels SR, Dishman RK, Gutin B, Hergenroeder AC, Must A, Nixon PA, Pivarnik JM, Rowland T, Trost S, Trudeau F. Evidence-based physical activity for school-age youth. J Pediatr. 2005;146:732–7.

    Article  PubMed  Google Scholar 

  48. Danforth JS, Allen KD, Fitterling JM, Danforth JA, Farrar D, Brown M, Drabman RS. Exercise as a treatment of hypertension in low-socioeconomic-status black children. J Consult Clin Psychol. 1990;58: 237–9.

    Article  PubMed  CAS  Google Scholar 

  49. Hansen HS, Froberg K, Hyldebrandt N, Nielsen JR. A controlled study of eight months of physical training and reduction of blood pressure in children: the Odense schoolchild study. BMJ. 1991;303:682–5.

    Article  PubMed  CAS  Google Scholar 

  50. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics. 2011;128:s213–56.

    Google Scholar 

  51. Demorest RA, Washington RL, Council on Sports Medicine and Fitness. Athletic participation by children and adolescents who have systemic hypertension. Pediatrics. 2010;125:1287–94.

    Article  PubMed  Google Scholar 

  52. Tu W, Eckert GJ, DiMeglio LA, Yu Z, Jung J, Pratt JH. Intensified effect of adiposity on blood pressure in overweight and obese children. Hypertension. 2011; 58:818–24.

    Article  PubMed  CAS  Google Scholar 

  53. Munter P, He J, Cutler JA, Wildman RP, Whelton PK. Trends in blood pressure among children and adolescents. JAMA. 2004;291:2107–13.

    Article  Google Scholar 

  54. Din-Dzietham R, Liu Y, Bielo MV, Shamsa F. High blood pressure trends in children and adolescents in national surveys, 1963–2002. Circulation. 2007;116:1488–96.

    Article  PubMed  Google Scholar 

  55. Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM. Prevalence of high body mass index in US children and adolescents, 2007–2008. JAMA. 2012;303: 242–9.

    Article  Google Scholar 

  56. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The seventh report of the joint national committee on prevention, detection, evaluation and treatment of high blood pressure: the JNC 7 report. JAMA 2003;289: 2560–72.

    Google Scholar 

  57. Kirk S, Zeller M, Claytor R, Santangelo M, Khoury PR, Daniels S. The relationship of health outcomes to improvement in body mass index in children and adolescents. Obes Res. 2005;13:876–82.

    Article  PubMed  Google Scholar 

  58. Reinehr T, Andler W. Changes in the atherogenic risk factor profile according to degree of weight loss. Arch Dis Child. 2004;89:419–22.

    Article  PubMed  CAS  Google Scholar 

  59. Barlow SE, Expert Committee. Expert committee recommendations regarding the prevention, assessment and treatment of child and adolescent overweight and obesity: summary report. Pediatrics. 2007;120: S164–92.

    Article  PubMed  Google Scholar 

  60. Schwartz RP, Hamre R, Dietz WH, Wasserman RC, Siora EJ, Myers EF, Sullivan S, Rockett H, Thomas KA, Dumitru G, Resnicow KA. Office-based motivational interviewing to prevent childhood obesity: a feasibility study. Arch Pediatr Adolesc Med. 2007;161:495–501.

    Article  PubMed  Google Scholar 

  61. Barnes VA, Treiber FA, Davis H. Impact of transcendental meditation on cardiovascular function at rest and during acute stress in adolescents with high normal blood pressure. J Psychosom Res. 2001;51: 597–605.

    Article  PubMed  CAS  Google Scholar 

  62. Ewart CK, Harris WL, Iwata MM, Coates TJ, Bullock R, Simon B. Feasibility and effectiveness of school-based relaxation in lowering blood pressure. Health Psychol. 1987;65:399–416.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sarah C. Couch Ph.D., RD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media New York

About this chapter

Cite this chapter

Couch, S.C., Daniels, S.R. (2013). Non-pharmacologic Treatment of Pediatric Hypertension. In: Flynn, J., Ingelfinger, J., Portman, R. (eds) Pediatric Hypertension. Clinical Hypertension and Vascular Diseases. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-490-6_35

Download citation

  • DOI: https://doi.org/10.1007/978-1-62703-490-6_35

  • Published:

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-489-0

  • Online ISBN: 978-1-62703-490-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics