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Deciphering the Adult Brain: From Neuroanatomy to Behavior

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The Making and Un-Making of Neuronal Circuits in Drosophila

Part of the book series: Neuromethods ((NM,volume 69))

Abstract

The Drosophila brain with an estimated 100,000 neurons provides at once an excellent opportunity to describe a complex brain in great detail and to identify the genetic and neurobiological basis of a wide array of behaviors. Furthermore, the sequencing of the genome with the concurrent identification of the elaborate homology of human and Drosophila genes and numerous functional studies have established the high relevance of Drosophila to understand diseases of the human brain. An overview is provided of available techniques to visualize neurons and neural circuitry and to study their function in behavior. Various resources are listed, and future and emerging technologies are discussed.

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Authors and Affiliations

  1. Laboratory of Behavioral and Developmental Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium

    Liesbeth Zwarts, Jason Clements & Patrick Callaerts

  2. VIB Center for the Biology of Disease, KU Leuven, Leuven, Belgium

    Liesbeth Zwarts, Jason Clements & Patrick Callaerts

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  1. Liesbeth Zwarts
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  2. Jason Clements
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  1. Center for Human Genetics, Laboratory of Neurogenetics, Katholieke Universiteit Leuven, Herestraat 49, Leuven, 3000, Belgium

    Bassem A. Hassan

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Zwarts, L., Clements, J., Callaerts, P. (2012). Deciphering the Adult Brain: From Neuroanatomy to Behavior. In: Hassan, B. (eds) The Making and Un-Making of Neuronal Circuits in Drosophila. Neuromethods, vol 69. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-830-6_1

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