Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 772)
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Table of contents (28 protocols)
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Front Matter
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Characterizing the Genome
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Front Matter
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Targeting Regions of the Genome
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Front Matter
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Measuring Genetic Diversity
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Front Matter
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Obtaining Candidate Gene Sequences
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Front Matter
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About this book
We are entering a particularly fruitful period in evolutionary genetics, as rapid technological progress transforms the investigation of genetic variation within and between species. Molecular Methods for Evolutionary Genetics is a collection of advanced molecular biology protocols and general overviews intended to represent the essential methods currently bringing evolutionary genetics to fruition. Divided into six thematic sections, this volume covers methods for characterizing genomes, diverse approaches to enrich DNA for subsets of the genome prior to sequencing, and state-of-the-art protocols for sampling genetic variation for genetic mapping studies and population genetic studies (RAD sequencing, Sequenom, microarrays, etc.). The volume concludes by focusing on methods to study candidate genes, from obtaining their sequences and analyzing their transcripts to experimentally manipulating their activities in vivo. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and accessible, Molecular Methods for Evolutionary Genetics serves as a rich resource to biologists interested in evolution, whether they be specialists or beginners in molecular biology.
Editors and Affiliations
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CNRS UMR7592, Université Paris VII, Paris, France
Virginie Orgogozo
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Dept. Biology, New York University, New York, USA
Matthew V. Rockman
Bibliographic Information
Book Title: Molecular Methods for Evolutionary Genetics
Editors: Virginie Orgogozo, Matthew V. Rockman
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-228-1
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-61779-227-4Published: 29 September 2011
Softcover ISBN: 978-1-4939-5861-0Published: 23 August 2016
eBook ISBN: 978-1-61779-228-1Published: 09 November 2011
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVI, 503
Number of Illustrations: 77 b/w illustrations, 4 illustrations in colour
Topics: Human Genetics, Gene Function