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Growth Hormone Treatment of the Short Child Born Small for Gestational Age

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Pediatric Endocrinology

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

Intrauterine growth retardation (IUGR) is a pathologic condition where fetal growth is restrained by either extrinsic (maternal) factors or a disorder intrinsic to the fetus itself. This is a significant problem because of the morbidity that accompanies IUGR. The effect of IUGR on subsequent growth and its amelioration by growth hormone (GH) is the focus of this chapter.

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Notes

  1. 1.

    Note added in proof: Since submission of this work, there has been a preliminary report from the European Union SAGhE study suggesting an increase in overall mortality in children treated with growth hormone (Carel et al, J Clin Endocrinol Metab 97:416-25, 2012). Though this was not confirmed in a parallel study (Savendahl et al, J Clin Endocrinol Metab 97:E213-7, 2012), readers are encouraged to examine future reports on this topic.

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  1. Department of Pediatrics, Pediatric Endocrinology, University of Oklahoma Health Sciences Center, 1200 Children’s Way, Suite 4500, Oklahoma City, OK, 73104-4600, USA

    Steven D. Chernausek M.D.

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  1. Steven D. Chernausek M.D.
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  1. School of Medicine, Department of Pediatrics, The Johns Hopkins University, 600 North Wolfe St., Baltimore, 21287, Maryland, USA

    Sally Radovick

  2. , Department of Pediatrics, Children's Hospital of Buffalo, 219 Bryant St., Buffalo, 14222, New York, USA

    Margaret H. MacGillivray

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Chernausek, S.D. (2013). Growth Hormone Treatment of the Short Child Born Small for Gestational Age. In: Radovick, S., MacGillivray, M. (eds) Pediatric Endocrinology. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-395-4_5

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