Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1912)
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Table of contents (17 protocols)
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Front Matter
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Overview of Disease-Specific ncRNAs
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Front Matter
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Computational Methods and Workflows for ncRNA Discovery and Annotation Based on High-Throughput Sequencing Data
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Front Matter
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Bioinformatics Tools and Databases for ncRNA Analyses
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Front Matter
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Network-Based Methods for Characterizing ncRNA Function
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Front Matter
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Kinetic Modeling of ncRNA-Mediated Gene Regulation
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Front Matter
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About this book
This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Computational Biology of Non-Coding RNA: Methods and Protocols aims to provide a state-of-the-art collection of computational methodsand approaches that will be of value to researchers interested in ncRNA field.
Editors and Affiliations
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Department of Dermatology, Erlangen University Hospital, Erlangen, Germany
Xin Lai, Julio Vera
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Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
Shailendra K. Gupta
Bibliographic Information
Book Title: Computational Biology of Non-Coding RNA
Book Subtitle: Methods and Protocols
Editors: Xin Lai, Shailendra K. Gupta, Julio Vera
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8982-9
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2019
Hardcover ISBN: 978-1-4939-8981-2Published: 12 January 2019
eBook ISBN: 978-1-4939-8982-9Published: 11 January 2019
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 451
Number of Illustrations: 13 b/w illustrations, 65 illustrations in colour
Topics: Bioinformatics, Human Genetics, Computational Biology/Bioinformatics