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Malignant Fibrous, Fibrohistiocytic, and Myofibroblastic Tumors

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Soft Tissue Tumors of the Skin

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Abstract

This chapter covers fibrous, fibrohistiocytic, and myofibroblastic tumors that have metastatic potential. Congenital/infantile fibrosarcoma is the exception to that rule, as it behaves less aggressively than its adult counterpart. Adult-type fibrosarcoma is a diagnosis in decline due to the recognition of distinct variants: low-grade fibromyxoid sarcoma, sclerosing epithelioid fibrosarcoma, myxofibrosarcoma, low-grade myofibroblastic sarcoma (myofibrosarcoma), and myxoinflammatory fibroblastic sarcoma. Undifferentiated pleomorphic sarcoma may also present as a superficial tumor and will be briefly discussed. The chapter closes with a discussion of undifferentiated pleomorphic sarcomas of the skin, specifically atypical fibroxanthoma and pleomorphic dermal sarcoma.

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Authors and Affiliations

  1. Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA

    Aaron M. Udager & Rajiv M. Patel

  2. Department of Pathology, Oregon Health and Science University School of Medicine, Portland, OR, USA

    Reena Singh

  3. Department of Pathology, Cleveland Clinic, Cleveland, OH, USA

    Steven D. Billings

Authors
  1. Aaron M. Udager
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  2. Reena Singh
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  3. Steven D. Billings
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  4. Rajiv M. Patel
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Correspondence to Rajiv M. Patel .

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Editors and Affiliations

  1. Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA

    Steven D. Billings

  2. Departments of Pathology and Dermatology, University of Michigan Medical Center, Ann Arbor, MI, USA

    Rajiv M. Patel

  3. Department of Pathology and Laboratory Medicine, University of Wisconsin–Madison, Madison, WI, USA

    Darya Buehler

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Udager, A.M., Singh, R., Billings, S.D., Patel, R.M. (2019). Malignant Fibrous, Fibrohistiocytic, and Myofibroblastic Tumors. In: Billings, S., Patel, R., Buehler, D. (eds) Soft Tissue Tumors of the Skin. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-8812-9_6

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  • DOI: https://doi.org/10.1007/978-1-4939-8812-9_6

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