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Deriving and Testing the Validity of Cognitive Reserve Candidates

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Biomarkers for Preclinical Alzheimer’s Disease

Part of the book series: Neuromethods ((NM,volume 137))

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Abstract

Empirical support has established cognitive reserve (CR) well as a concept since its inception three decades ago, and most brain researchers subscribe to some version of CR as a collection of subject factors that influence cognitive performance beyond simple brain structural health. We give a simple but precise analytic recipe to test requirements for any plausible cognitive reserve candidate based on brain imaging. Gradations of partial fulfillment of some but not all of these requirements are possible.

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Author information

Authors and Affiliations

  1. Cognitive Neuroscience Division, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA

    Yaakov Stern & Christian Habeck

Authors
  1. Yaakov Stern
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  2. Christian Habeck
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Corresponding author

Correspondence to Yaakov Stern .

Editor information

Editors and Affiliations

  1. Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany

    Robert Perneczky

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Stern, Y., Habeck, C. (2018). Deriving and Testing the Validity of Cognitive Reserve Candidates. In: Perneczky, R. (eds) Biomarkers for Preclinical Alzheimer’s Disease. Neuromethods, vol 137. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7674-4_4

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  • DOI: https://doi.org/10.1007/978-1-4939-7674-4_4

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7673-7

  • Online ISBN: 978-1-4939-7674-4

  • eBook Packages: Springer Protocols

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