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Procedures of Necropsy and Tissue Sampling

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Drug Safety Evaluation

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1641))

Abstract

Necropsy is a major step of most studies using laboratory animals. During necropsy, tissue and organ noticeable grossly changes should be recorded and critical tissue samples may be stored for the subsequent evaluation. It is therefore important that the personnel in charge of this key experimental step to be adequately trained and aware of the study endpoints.

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Authors and Affiliations

  1. IMMR, 42, Boulevard Jourdan, 75014, Paris, France

    Laurence Fiette D.V.M., D.E.S.A.P.V., Ph.D.

  2. Preclinical Safety, Sanofi R&D, 13, Quai Jules Guesde, 94403, Vitry-sur-Seine, France

    Mohamed Slaoui D.V.M., D.E.S.A.P.V.

  3. Translational Medicine and Early Development, Biomarkers and Clinical Bioanalyses, Sanofi R&D, 13, Quai Jules Guesde, 94403, Vitry-sur-Seine, France

    Anne-Laure Bauchet D.V.M., D.E.C.V.P., Ph.D.

Authors
  1. Laurence Fiette D.V.M., D.E.S.A.P.V., Ph.D.
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  2. Mohamed Slaoui D.V.M., D.E.S.A.P.V.
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  3. Anne-Laure Bauchet D.V.M., D.E.C.V.P., Ph.D.
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Correspondence to Mohamed Slaoui D.V.M., D.E.S.A.P.V. .

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  1. Preclinical Safety, Sanofi, R&D, Vitry-sur-Seine, France

    Jean-Charles Gautier

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Fiette, L., Slaoui, M., Bauchet, AL. (2017). Procedures of Necropsy and Tissue Sampling. In: Gautier, JC. (eds) Drug Safety Evaluation. Methods in Molecular Biology, vol 1641. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7172-5_3

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  • DOI: https://doi.org/10.1007/978-1-4939-7172-5_3

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