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Silica Nanomaterials

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Nanomaterials in Pharmacology

Part of the book series: Methods in Pharmacology and Toxicology ((MIPT))

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Abstract

Ultrafine mechanisms are efficiently working in biological systems. Fabrication of desired nanostructured materials has been paid much attention in biology, biochemistry, and pharmaceutical sciences. For these demands, nanostructured inorganic materials have to be more utilized in biological pharmaceutical fields. Among numerous candidates of inorganic materials, silica is the strongest candidate for use because silica is very abundant in nature and has low toxicity with huge knowledge on nanostructure fabrication. In this chapter, mesoporous silica and layer-by-layer assembly are first introduced, followed by description of emerging materials such as silica flake-shell capsule and silica nanostructure plate with examples for their usages in drug delivery and gene transfections.

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Acknowledgement

This work was partly supported by World Premier International Research Center Initiative (WPI Initiative), MEXT, Japan and Core Research for Evolutional Science and Technology (CREST) program of Japan Science and Technology Agency (JST), Japan.

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Authors and Affiliations

  1. World Premier International (WPI) Research Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, 305-0044, Japan

    Katsuhiko Ariga & Qingmin Ji

  2. Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan

    Katsuhiko Ariga

Authors
  1. Katsuhiko Ariga
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  2. Qingmin Ji
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Correspondence to Katsuhiko Ariga .

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Editors and Affiliations

  1. Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA

    Zheng-Rong Lu

  2. Laboratory of Drug Delivery System, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan

    Shinji Sakuma

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Ariga, K., Ji, Q. (2016). Silica Nanomaterials. In: Lu, ZR., Sakuma, S. (eds) Nanomaterials in Pharmacology. Methods in Pharmacology and Toxicology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3121-7_7

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  • DOI: https://doi.org/10.1007/978-1-4939-3121-7_7

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3120-0

  • Online ISBN: 978-1-4939-3121-7

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