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Normal Diffusion Tensor Imaging-Based White Matter Anatomy

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Diffusion Tensor Imaging
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Abstract

In this chapter, an overview is given of how diffusion tensor imaging (DTI) can be used to perform the reconstruction of three-dimensional white matter tracts. This chapter includes a brief description of the method and the applied measurement protocol. It also contains a section on two-dimensional anatomical views of DTI-derived fiber trajectories in all three standard radiological views using color maps and concludes with a three-dimensional representation of the major white matter tracts in the human cerebrum.

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References

  1. Mori S, van Zijl PC. Fiber tracking: principles and strategies - a technical review. NMR Biomed. 2002;15(7-8):468–80.

    Article  PubMed  Google Scholar 

  2. Mori S, Kaufmann WE, Davatzikos C, Stieltjes B, Amodei L, Fredericksen K, Pearlson GD, Melhem ER, Solaiyappan M, Raymond GV, Moser HW, van Zijl PC. Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking. Magn Reson Med. 2002;47(2):215–23.

    Article  PubMed  Google Scholar 

  3. Stieltjes B, Kaufmann WE, van Zijl PC, Fredericksen K, Pearlson GD, Solaiyappan M, Mori S. Diffusion tensor imaging and axonal tracking in the human brainstem. NeuroImage. 2001;14(3):723–35.

    Article  CAS  PubMed  Google Scholar 

  4. Xue R, van Zijl PC, Crain BJ, Solaiyappan M, Mori S. In vivo three-dimensional reconstruction of rat brain axonal projections by diffusion tensor imaging. Magn Reson Med. 1999;42(6):1123–7.

    Article  CAS  PubMed  Google Scholar 

  5. Mori S, Crain BJ, Chacko VP, van Zijl PC. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol. 1999;45(2):265–9.

    Article  CAS  PubMed  Google Scholar 

  6. Hahn HK, Klein J, Nimsky C, Rexilius J, Peitgen HO. Uncertainty in diffusion tensor based fibre tracking. Acta Neurochir Suppl. 2006;98:33–41.

    Article  CAS  PubMed  Google Scholar 

  7. Conturo TE, Lori NF, Cull TS, Akbudak E, Snyder AZ, Shimony JS, McKinstry RC, Burton H, Raichle ME. Tracking neuronal fiber pathways in the living human brain. Proc Natl Acad Sci U S A. 1999;96(18):10422–7.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  8. Reisert M, Mader I, Anastasopoulos C, Weigel M, Schnell S, Kiselev V. Global fiber reconstruction becomes practical. NeuroImage. 2011;54(2):955–62.

    Article  PubMed  Google Scholar 

  9. Kreher BW, Mader I, Kiselev VG. Gibbs tracking: a novel approach for the reconstruction of neuronal pathways. Magn Reson Med. 2008;60(4):953–63.

    Article  CAS  PubMed  Google Scholar 

  10. Mangin JF, Poupon C, Cointepas Y, Riviere D, Papadopoulos-Orfanos D, Clark CA, Regis J, Le Bihan D. A framework based on spin glass models for the inference of anatomical connectivity from diffusion-weighted MR data - a technical review. NMR Biomed. 2002;15(7-8):481–92.

    Article  PubMed  Google Scholar 

  11. Fillard P, Descoteaux M, Goh A, Gouttard S, Jeurissen B, Malcolm J, Ramirez-Manzanares A, Reisert M, Sakaie K, Tensaouti F, Yo T, Mangin JF, Poupon C. Quantitative evaluation of 10 tractography algorithms on a realistic diffusion MR phantom. NeuroImage. 2011;56(1):220–34.

    Article  PubMed  Google Scholar 

MITK Diffusion Imaging

  1. Fritzsche KH, Neher PF, Reicht I, van Bruggen T, Goch C, Reisert M, Nolden M, Zelzer S, Meinzer HP, Stieltjes B. MITK Diffusion Imaging. Methods Inf Med. 2012;51(5):441–8.

    Google Scholar 

  2. Stieltjes B, Brunner R, Fritzsche KH, Laun FB. Diffusion tensor imaging; introduction and atlas. Heidelberg: Springer; 2012.

    Google Scholar 

Suggested Reading

  • Nieuwenhuys R, Voogd J, Van Huijzen C. The human central nervous system; a synopsis and atlas. New York: Springer; 1988. A great anatomical work of reference for brain anatomy.

    Book  Google Scholar 

  • Johansen-Berg H, Behrens TEJ. Diffusion MRI; from quantitative measurement to in vivo neuroanatomy. Amsterdam: Academic; 2009. Chapters 5-7 give a great overview of the relationship between microstructure and DTI-derived parameters.

    Google Scholar 

  • Stieltjes B, Brunner R, Fritzsche KH, Laun FB. Diffusion tensor imaging; introduction and atlas. New York: Springer; 2012. Gives a more detailed introduction to diffusion imaging and rich anatomical reference.

    Google Scholar 

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Correspondence to Bram Stieltjes MD, PhD .

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Stieltjes, B. (2016). Normal Diffusion Tensor Imaging-Based White Matter Anatomy. In: Van Hecke, W., Emsell, L., Sunaert, S. (eds) Diffusion Tensor Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3118-7_12

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  • DOI: https://doi.org/10.1007/978-1-4939-3118-7_12

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-3117-0

  • Online ISBN: 978-1-4939-3118-7

  • eBook Packages: MedicineMedicine (R0)

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