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Sex-Related Difference in Muscle Deoxygenation Responses Between Aerobic Capacity-Matched Elderly Men and Women

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Oxygen Transport to Tissue XXXVII

Abstract

Muscle O2 dynamics during ramp cycling exercise were compared between aerobic capacity-matched elderly men (n = 8, age 65 ± 2 years) and women (n = 8, age 66 ± 3 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (Δdeoxy-Hb) and total hemoglobin concentration (Δtotal-Hb) were monitored continuously during exercise in the vastus lateralis (VL) and gastrocnemius medialis (GM) by near infrared spatial resolved spectroscopy. SmO2 was significantly higher during exercise in women than in men in VL, but not in GM. In VL, Δdeoxy-Hb and Δtotal-Hb were significantly higher in men than in women, especially during high intensity exercise. However, no significant difference was observed in Δdeoxy-Hb or Δtotal-Hb in GM. Sex-related differences in muscle deoxygenation response may be heterogeneous among leg muscles in elderly subjects.

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Acknowledgments

The authors are grateful for revision of this manuscript by Andrea Hope. This study was supported in part by Grant-in-Aid for scientific research from Japan Society for the Promotion of Science (246298) to S.T.

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Correspondence to Shun Takagi .

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Takagi, S. et al. (2016). Sex-Related Difference in Muscle Deoxygenation Responses Between Aerobic Capacity-Matched Elderly Men and Women. In: Elwell, C.E., Leung, T.S., Harrison, D.K. (eds) Oxygen Transport to Tissue XXXVII. Advances in Experimental Medicine and Biology, vol 876. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3023-4_7

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