Abstract
Muscle O2 dynamics during ramp cycling exercise were compared between aerobic capacity-matched elderly men (n = 8, age 65 ± 2 years) and women (n = 8, age 66 ± 3 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (Δdeoxy-Hb) and total hemoglobin concentration (Δtotal-Hb) were monitored continuously during exercise in the vastus lateralis (VL) and gastrocnemius medialis (GM) by near infrared spatial resolved spectroscopy. SmO2 was significantly higher during exercise in women than in men in VL, but not in GM. In VL, Δdeoxy-Hb and Δtotal-Hb were significantly higher in men than in women, especially during high intensity exercise. However, no significant difference was observed in Δdeoxy-Hb or Δtotal-Hb in GM. Sex-related differences in muscle deoxygenation response may be heterogeneous among leg muscles in elderly subjects.
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References
Murias JM, Keir DA, Spencer MD et al (2013) Sex-related differences in muscle deoxygenation during ramp incremental exercise. Respir Physiol Neurobiol 189:530–536
Peltonen JE, Hägglund H, Koskela-Koivisto T et al (2013) Alveolar gas exchange, oxygen delivery and tissue deoxygenation in men and women during incremental exercise. Respir Physiol Neurobiol 188:102–112
Bhambhani Y, Maikala R, Buckley S (1998) Muscle oxygenation during incremental arm and leg exercise in men and women. Eur J Appl Physiol Occup Physiol 78:422–431
Takagi S, Kime R, Murase N et al (2013) Aging affects spatial distribution of leg muscle oxygen saturation during ramp cycling exercise. Adv Exp Med Biol 789:157–162
Martin WH 3rd, Ogawa T, Kohrt WM et al (1991) Effects of aging, gender, and physical training on peripheral vascular function. Circulation 84:654–664
Niwayama M, Suzuki H, Yamashita T et al (2012) Error factors in oxygenation measurement using continuous wave and spatially resolved near-infrared spectroscopy. J Jpn Coll Angiol 52:211–215
Reybrouck T, Fagard R (1999) Gender differences in the oxygen transport system during maximal exercise in hypertensive subjects. Chest 115:788–792
Hickner RC, Kemeny G, McIver K et al (2003) Lower skeletal muscle nutritive blood flow in older women is related to eNOS protein content. J Gerontol A Biol Sci Med Sci 58:20–25
Moreau KL, Donato AJ, Tanaka H et al (2003) Basal leg blood flow in healthy women is related to age and hormone replacement therapy status. J Physiol 547(Pt 1):309–316
Cavalcanti-de-Albuquerque JP, Salvador ID, Martins EG et al (2014) Role of estrogen on skeletal muscle mitochondrial function in ovariectomized rats: a time course study in different fiber types. J Appl Physiol 116:779–789
Benelli P, Ditroilo M, Forte R et al (2007) Assessment of post-competition peak blood lactate in male and female master swimmers aged 40–79 years and its relationship with swimming performance. Eur J Appl Physiol 99:685–693
Thompson JR, Swanson SA, Casale GP et al (2013) Gastrocnemius mitochondrial respiration: are there any differences between men and women? J Surg Res 185:206–211
Green HJ, Fraser IG, Ranney DA (1984) Male and female differences in enzyme activities of energy metabolism in vastus lateralis muscle. J Neurol Sci 65:323–331
Acknowledgments
The authors are grateful for revision of this manuscript by Andrea Hope. This study was supported in part by Grant-in-Aid for scientific research from Japan Society for the Promotion of Science (246298) to S.T.
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Takagi, S. et al. (2016). Sex-Related Difference in Muscle Deoxygenation Responses Between Aerobic Capacity-Matched Elderly Men and Women. In: Elwell, C.E., Leung, T.S., Harrison, D.K. (eds) Oxygen Transport to Tissue XXXVII. Advances in Experimental Medicine and Biology, vol 876. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3023-4_7
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DOI: https://doi.org/10.1007/978-1-4939-3023-4_7
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