Abstract
The prefrontal cortex (PFC) plays an important role in emotion and emotional regulation. The valence asymmetry hypothesis, proposes that the left/right asymmetry of the PFC activity is correlated with specific emotional responses to stressors. However, this hypothesis still seems to leave room for clarifying neurophysiological mechanisms. The purpose of the present study was to investigate the effects of stimuli with positive and negative valence sounds (hereafter PS, NS) selected from the International Affective Digitized Sounds-2 on physiological and physiological responses, including PFC activity in normal participants. We studied the effect of both stimuli using 12 normal subjects (mean age 26.8 years) on cerebral blood oxygenation in the bilateral PFC by a multi-channel NIRS, alpha wave appearance rate in theta, alpha, beta by EEG, autonomic nervous function by heart rate, and emotional conditions by the State-Trait Anxiety Inventory (STAI) and the visual analogue scale (VAS). PS was selected over 7.00 and NS were fewer than 3.00 in the Pleasure values. Sounds were recorded during 3 s and reproduced at random using software. Every task session was designed in a block manner: seven rests with Brown Noise (30 s) and six tasks (30 s) blocks. All participants performed each session in random order with eyes closed. A paired Student’s t-test was used for comparisons (P < 0.05). PFC activity showed increases bilaterally during both stimuli with a greater activation of the left side in PS and a tendency of more activation by NS in the right PFC. Significantly greater alpha wave intensity was obtained in PS. Heart rate tended to show smaller values in PS. The STAI level tended to show smaller values in PS, and a significantly greater VAS score was obtained in PS which indicated ‘pleasant’. Despite the limitations of this study such as the low numbers of the subjects, the present study indicated that PS provided pleasant psychological and physiological responses and NS unpleasant responses. The PFC was activated bilaterally, implying a valence effect with the possibility of a dominant side.
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References
Liu X, Iwanaga K, Koda S (2011) Circulatory and central nervous system responses to different types of mental stress. Ind Health 49:265–273
Tanida M, Katsuyama M, Sakatani K (2007) Relation between mental stress-induced prefrontal cortex activity and skin conditions: a near-infrared spectroscopy study. Brain Res 1184:210–216
Tanida M, Sakatani K, Takano R et al (2004) Relation between asymmetry of prefrontal cortex activities and the autonomic nervous system during a mental arithmetic task: near infrared spectroscopy study. Neurosci Lett 369:69–74
Arnsten AF (2009) Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci 10:410–422
Buijs RM, Van Eden CG (2000) The integration of stress by the hypothalamus, amygdala and prefrontal cortex: balance between the autonomic nervous system and the neuroendocrine system. Prog Brain Res 126:117–132
Davidson RJ, Jackson DC, Kalin NH (2000) Emotion, plasticity, context, and regulation: perspectives from affective neuroscience. Psychol Bull 126:890–909
Ishikawa W, Sato M, Fukuda Y et al (2014) Correlation between asymmetry of spontaneous oscillation of hemodynamic changes in the prefrontal cortex and anxiety levels: a near-infrared spectroscopy study. J Biomed Opt 19:027005
Davidson RJ (2003) Affective neuroscience and psychophysiology: toward a synthesis. Psychophysiology 40:655–665
Coan JA, Allen JJ (2004) Frontal EEG asymmetry as a moderator and mediator of emotion. Biol Psychol 67:7–49
Royet JP, Zald D, Versace R et al (2000) Emotional responses to pleasant and unpleasant olfactory, visual, and auditory stimuli: a positron emission tomography study. J Neurosci 20:7752–7759
Soares AP, Pinheiro AP, Costa A et al (2013) Affective auditory stimuli: adaptation of the International Affective Digitized Sounds (IADS-2) for European Portuguese. Behav Res Methods 45:1168–1181
Stevenson RA, James TW (2008) Affective auditory stimuli: characterization of the International Affective Digitized Sounds (IADS) by discrete emotional categories. Behav Res Methods 40:315–321
Bradley MM, Lang PJ (2007) The International Affective Digitized Sounds (2nd Edn; IADS-2): affective ratings of sounds and instruction manual. Technical report B-3. University of Florida, NIH Center for the Study of Emotion and Attention, Gainesville
Van de Kar LD, Blair ML (1999) Forebrain pathways mediating stress-induced hormone secretion. Front Neuroendocrinol 20:1–48
Ritvanen T, Louhevaara V, Helin P et al (2006) Responses of the autonomic nervous system during periods of perceived high and low work stress in younger and older female teachers. Appl Ergon 37:311–318
Nishifuji S (2011) EEG recovery enhanced by acute aerobic exercise after performing mental task with listening to unpleasant sound. Conference proceedings: annual international conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Conference, vol 2011, pp 3837–3840
Horii A, Yamamura C, Katsumata T, Uchiyama A (2004) Physiological response to unpleasant sounds. J Int Soc Life Inform Sci 22:536–544
Altenmuller E, Schurmann K, Lim VK et al (2002) Hits to the left, flops to the right: different emotions during listening to music are reflected in cortical lateralisation patterns. Neuropsychologia 40:2242–2256
Acknowledgments
This research was partly supported by Japan Science and Technology Agency, under Strategic Promotion of Innovative Research and Development Program, and a Grant-in-Aid from the Ministry of Education, Culture, Sports, Sciences and Technology of Japan (Grant-in-Aid for Scientific Research 22592162, 25463025, and 25463024, Grant-in-Aid for Exploratory Research 25560356), and grants from Alpha Electron Co., Ltd. (Fukushima, Japan) and Iing Co., Ltd. (Tokyo, Japan).
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Takeda, T. et al. (2016). Influence of Pleasant and Unpleasant Auditory Stimuli on Cerebral Blood Flow and Physiological Changes in Normal Subjects. In: Elwell, C.E., Leung, T.S., Harrison, D.K. (eds) Oxygen Transport to Tissue XXXVII. Advances in Experimental Medicine and Biology, vol 876. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3023-4_38
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DOI: https://doi.org/10.1007/978-1-4939-3023-4_38
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