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Sexual Disorders: Dysfunction, Gender Identity and Paraphilias

  • Chapter
The Medical Basis of Psychiatry

Abstract

Sexual disorders in the Diagnostic and Statistical Manual for DSM-5 are divided into three major categories: 1) sexual dysfunctions, problems in sexual desire or disturbances in the psychophysiologic changes that are part of the sexual response cycle, 2) Paraphilias, which involve recurrent intense sexual urges or fantasies, or behaviors that involve unusual objects, activities, or situations that are by and large not culturally sanctioned, and 3) gender identity disorders, which are characterized by dissatisfaction with one’s biological gender and often a desire to undergo gender reassignment. In this chapter we will review the diagnostic criteria, prevalence, etiology, assessment and treatment of these disorders.

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Notes

  1. 1.

     Editor’s comments: A new FDA-approved medication named Flibanserin has been introduced into the market for the treatment of female arousal disorder, recently.

References

  1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-5. 5th ed. Arlington, VA: American Psychiatric Association Publishing; 2013.

    Google Scholar 

  2. World Health Organization. Defining sexual health. Report of a technical consultation on sexual health, 28–31 January 2002, Geneva

    Google Scholar 

  3. World Health Organization. Education and treatment in human sexuality: the training of health professionals. Geneva, 1975 (WHO Technical Report Series No. 572)

    Google Scholar 

  4. Coleman E. Promoting sexual health and responsible sexual behavior: an introduction. J Sex Res 2002;39:3–6.

    Article  PubMed  Google Scholar 

  5. Robinson BB, Bockting WO, Rosser BR, Miner M, Coleman E. The Sexual Health Model: application of a sexological approach to HIV prevention. Health Educ Res 2002;17:43–57.

    Article  PubMed  Google Scholar 

  6. Laumann EO. The social organization of sexuality: sexual practices in the United States. Chicago: University of Chicago Press; 1994.

    Google Scholar 

  7. Rosen RC, Leiblum SR. Treatment of sexual disorders in the 1990s: an integrated approach. J Consult Clin Psychol 1995;63:877–890.

    Article  CAS  PubMed  Google Scholar 

  8. Drugs that cause sexual dysfunction: an update. Med Lett Drugs Ther 1992;34:73–78.

    Google Scholar 

  9. Anastasiadis AG, Davis AR, Salomon L, Burchardt M, Shabsigh R. Hormonal factors in female sexual dysfunction. Curr Opin Urol 2002;12:503–507.

    Article  PubMed  Google Scholar 

  10. Mathur RS, Landgrebe SC, Moody LO, Semmens JP, Williamson HO. The effect of estrogen treatment on plasma concentrations of steroid hormones, gonadotropins, prolactin and sex hormone-binding globulin in post-menopausal women. Maturitas 1985;7:129–133.

    Article  CAS  PubMed  Google Scholar 

  11. Robinson B, Feldman J, Striepe M, Raymond N, Mize S. Women's sexual health: an interdisciplinary approach to treating low sexual desire. Minn Med 2003;86:34–41.

    PubMed  Google Scholar 

  12. Heiman JR. Sexual dysfunction: overview of prevalence, etiological factors, and treatments. J Sex Res 2002;39:73–78.

    Article  PubMed  Google Scholar 

  13. Heaton JP. Neural and pharmacological determinants of erection. Int J Impot Res 1998;10:S34-S39.

    PubMed  Google Scholar 

  14. Rosen RC, Taylor JF, Leiblum SR, Bachmann GA. Prevalence of sexual dysfunction in women: results of a survey study of 329 women in an outpatient gynecological clinic. J Sex Marital Ther 1993;19:171–188.

    Article  CAS  PubMed  Google Scholar 

  15. Basson R. Clinical practice. Sexual desire and arousal disorders in women. N Engl J Med 2006;354:1497–1506.

    Article  CAS  PubMed  Google Scholar 

  16. Dunn KM, Croft PR, Hackett GI. Sexual problems: a study of the prevalence and need for health care in the general population. Fam Pract 1998;15:519–524.

    Article  CAS  PubMed  Google Scholar 

  17. Avis NE, Zhao X, Johannes CB, Ory M, Brockwell S, Greendale GA. Correlates of sexual function among multi-ethnic middle-aged women: results from the Study of Women's Health Across the Nation (SWAN). Menopause 2005;12:385–398.

    Article  PubMed  Google Scholar 

  18. van Lunsen RH, Laan E. Genital vascular responsiveness and sexual feelings in midlife women: psychophysiologic, brain, and genital imaging studies. Menopause 2004;11:741–748.

    Article  PubMed  Google Scholar 

  19. Stenberg A, Heimer G, Ulmsten U, Cnattingius S. Prevalence of genitourinary and other climacteric symptoms in 61-year-old women. Maturitas 1996;24:31–36.

    Article  CAS  PubMed  Google Scholar 

  20. Panzer C, Wise S, Fantini G, Kang D, Munarriz R, Guay A, Goldstein I. Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: a retrospective study in women with sexual dysfunction. J Sex Med 2006;3:104–113.

    Article  CAS  PubMed  Google Scholar 

  21. Santoro N, Torrens J, Crawford S, Allsworth JE, Finkelstein JS, Gold EB, Korenman S, Lasley WL, Luborsky JL, McConnell D, Sowers MF, Weiss G. Correlates of circulating androgens in mid-life women: the study of women's health across the nation. J Clin Endocrinol Metab 2005;90:4836–4845.

    Article  CAS  PubMed  Google Scholar 

  22. Taylor JF, Rosen RC, Leiblum SR. Self-report assessment of female sexual function: psychometric evaluation of the Brief Index of Sexual Functioning for Women. Arch Sex Behav 1994;23:627–643.

    Article  CAS  PubMed  Google Scholar 

  23. Laan E, Everaerd W. Physiological measures of vaginal vasocongestion. Int J Impot Res. 1998;10:S107-S110.

    PubMed  Google Scholar 

  24. Arlt W. Androgen therapy in women. Eur J Endocrinol 2006; 15:1–11.

    Article  CAS  Google Scholar 

  25. Basson R, Brotto LA. Sexual psychophysiology and effects of sildenafil citrate in oestrogenised women with acquired genital arousal disorder and impaired orgasm: a randomised controlled trial. BJOG 2003;110:1014–1024.

    Article  CAS  PubMed  Google Scholar 

  26. Basson R, McInnes R, Smith MD, Hodgson G, Koppiker N. Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder. J Womens Health Gend Based Med 2002;11:367–377.

    Article  PubMed  Google Scholar 

  27. Beutel ME, Weidner W, Brahler E. Epidemiology of sexual dysfunction in the male population. Andrologia 2006;38:115–121.

    Article  CAS  PubMed  Google Scholar 

  28. Wespes E, Amar E, Hatzichristou D, Hatzimouratidis K, Montorsi F, Pryor J, Vardi Y; EAU. EAU Guidelines on erectile dysfunction: an update. Eur Urol 2006;49:806–815.

    Article  PubMed  Google Scholar 

  29. Heiman JR, Grafton-Becker V. Orgasmic disorders in women. New York: Guilford Press; 1989.

    Google Scholar 

  30. Spector IP, Carey MP. Incidence and prevalence of the sexual dysfunctions: a critical review of the empirical literature. Arch Sex Behav 1990;19:389–408.

    Article  CAS  PubMed  Google Scholar 

  31. LoPiccolo J, Stock WE. Treatment of sexual dysfunction. J Consult Clin Psychol 1986;54:158–167.

    Article  CAS  PubMed  Google Scholar 

  32. Richardson D, Nalabanda A, Goldmeier D. Retarded ejaculation - a review. Int J STD AIDS 2006;17:143–150.

    Article  PubMed  Google Scholar 

  33. Gitlin MJ, Suri R, Altshuler L, Zuckerbrow-Miller J, Fairbanks L. Bupropion-sustained release as a treatment for SSRI-induced sexual side effects. J Sex Marital Ther 2002;28:131–138.

    Article  PubMed  Google Scholar 

  34. Segraves RT. Reversal by bethanechol of imipramine-induced ejaculatory dysfunction. Am J Psychiatry 1987;144:1243–1244.

    CAS  PubMed  Google Scholar 

  35. Balogh S, Hendricks SE, Kang J. Treatment of fluoxetine-induced anorgasmia with amantadine. J Clin Psychiatry 1992;53:212–213.

    CAS  PubMed  Google Scholar 

  36. Landen M, Eriksson E, Agren H, Fahlen T. Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors. J Clin Psychopharmacol 1999;19:268–271.

    Article  CAS  PubMed  Google Scholar 

  37. Shrivastava RK, Shrivastava S, Overweg N, Schmitt M. Amantadine in the treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors. J Clin Psychopharmacol 1995;15:83–84.

    Article  CAS  PubMed  Google Scholar 

  38. Mulhall JP. Current and future pharmacotherapeutic strategies in treatment of premature ejaculation. Urology 2006;67:9–16.

    Article  PubMed  Google Scholar 

  39. Rosen RC. Prevalence and risk factors of sexual dysfunction in men and women. Curr Psychiatr Rep 2000;2:189–195.

    Article  CAS  Google Scholar 

  40. Meana M, Binik YM. Painful coitus: a review of female dyspareunia. J Nerv Ment Dis 1994;182:264–272.

    Article  CAS  PubMed  Google Scholar 

  41. Ponticas Y. Sexual aversion versus hypoactive sexual desire: a diagnostic challenge. Psychiatr Med 1992;10:273–281.

    CAS  PubMed  Google Scholar 

  42. HBIGDA. The Standards of Care for Gender Identity Disorders. 6th version. 2001.

    Google Scholar 

  43. Feldman J, Bockting W. Transgender health. Minn Med 2003;86:25–32.

    PubMed  Google Scholar 

  44. Carlstedt A, Innala S, Brimse A, Soderstrom Anckarsater H. Mental disorders and DSM-IV paedophilia in 185 subjects convicted of sexual child abuse. Nord J Psychiatry 2005;59:534–537.

    Article  PubMed  Google Scholar 

  45. Weinberg TS. Sadomasochism and the social sciences: a review of the sociological literature and social psychological literature. Binghamton, NY: Harrington Park Press; 2006.

    Google Scholar 

  46. Briere J, Runtz M. University males' sexual interest in children: predicting potential indices of "pedophilia" in a nonforensic sample. Child Abuse Negl 1989;13:65–75.

    Article  CAS  PubMed  Google Scholar 

  47. Templeman TL, Stinnett RD. Patterns of sexual arousal and history in a "normal" sample of young men. Arch Sex Behav 1991;20:137–150.

    Article  CAS  PubMed  Google Scholar 

  48. Abel GG, Rouleau JL, Osborn CA. Sexual disorders. 2nd ed. Philadelphia: Saunders; 1994.

    Google Scholar 

  49. Grant JE. Clinical characteristics and psychiatric comorbidity in males with exhibitionism. J Clin Psychiatry 2005;66:1367–1371.

    Article  PubMed  Google Scholar 

  50. Allen A, Hollander E. Sexual Compulsions. Arlington, VA: American Psychiatric Association Publishing; 2005.

    Google Scholar 

  51. Chow EW, Choy AL. Clinical characteristics and treatment response to SSRI in a female pedophile. Arch Sex Behav 2002;31:211–215.

    Article  PubMed  Google Scholar 

  52. Grob CS. Female exhibitionism. J Nerv Ment Dis 1985;173:253–256.

    Article  CAS  PubMed  Google Scholar 

  53. Kafka MP, Hennen J. A DSM-IV Axis I comorbidity study of males (n=120) with paraphilias and paraphilia-related disorders. Sex Abuse 2002;14:349–366.

    PubMed  Google Scholar 

  54. Raymond NC, Coleman E, Ohlerking F, Christenson GA, Miner M. Psychiatric comorbidity in pedophilic sex offenders. Am J Psychiatry 1999;156:786–788.

    CAS  PubMed  Google Scholar 

  55. Abel GG, Osborn C. The paraphilias. The extent and nature of sexually deviant and criminal behavior. Psychiatr Clin North Am 1992;15:675–687.

    CAS  PubMed  Google Scholar 

  56. Firestone P, Kingston DA, Wexler A, Bradford JM. Long-term follow-up of exhibitionists: psychological, phallometric, and offense characteristics. J Am Acad Psychiatr Law 2006;34:349–359.

    Google Scholar 

  57. Heil P, Ahlmeyer S, Simons D. Crossover sexual offenses. Sex Abuse 2003;15:221–236.

    PubMed  Google Scholar 

  58. Bradford JM. The neurobiology, neuropharmacology, and pharmacological treatment of the paraphilias and compulsive sexual behaviour. Can J Psychiatry 2001;46:26–34.

    CAS  PubMed  Google Scholar 

  59. Meston CM, Frohlich PF. The neurobiology of sexual function. Arch Gen Psychiatry 2000;57:1012–1030.

    Article  CAS  PubMed  Google Scholar 

  60. Miller BL, Cummings JL, McIntyre H, Ebers G, Grode M. Hypersexuality or altered sexual preference following brain injury. J Neurol Neurosurg Psychiatry 1986;49:867–873.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  61. Comings DE, Comings BG. Tourette syndrome: clinical and psychological aspects of 250 cases. Am J Hum Genet 1985;37:435–450.

    CAS  PubMed  PubMed Central  Google Scholar 

  62. Burns JM, Swerdlow RH. Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign. Arch Neurol 2003;60:437–440.

    Article  PubMed  Google Scholar 

  63. Tost H, Vollmert C, Brassen S, Schmitt A, Dressing H, Braus DF. Pedophilia: neuropsychological evidence encouraging a brain network perspective. Med Hypotheses 2004;63:528–531.

    Article  PubMed  Google Scholar 

  64. Kafka MP. A monoamine hypothesis for the pathophysiology of paraphilic disorders. Arch Sex Behav 1997;26:343–358.

    Article  CAS  PubMed  Google Scholar 

  65. Kafka MP. The monoamine hypothesis for the pathophysiology of paraphilic disorders: an update. Ann N Y Acad Sci 2003;989:86–94.

    Article  PubMed  Google Scholar 

  66. Maletzky BM. The paraphilias: research and treatment. 2nd ed. New York: Oxford University Press; 2002.

    Google Scholar 

  67. Maletzky BM. Evolution, psychopathology, and sexual offending: aping our ancestors. Aggression and Violent Behavior: A Review 1996;1:369–373.

    Article  Google Scholar 

  68. McGuire RJ, Carlisle JM, Young BG. Sexual Deviations As Conditioned Behaviour: A Hypothesis. Behav Res Ther 1965;3:185–190.

    Article  CAS  PubMed  Google Scholar 

  69. Smallbone SW, Dadds MR. Attachment and coercive sexual behavior. Sex Abuse 2000;12:3–15.

    CAS  PubMed  Google Scholar 

  70. Dwyer SM. Treatment outcome study: 17 years after sexual offender treatment. Sex Abuse 1997;9:149–160.

    Google Scholar 

  71. Grossman LS, Martis B, Fichtner CG. Are sex offenders treatable? A research overview. Psychiatr Serv 1999;50:349–361.

    Article  CAS  PubMed  Google Scholar 

  72. Hanson RK, Gordon A, Harris AJ, Marques JK, Murphy W, Quinsey VL, Seto MC. First report of the collaborative outcome data project on the effectiveness of psychological treatment for sex offenders. Sex Abuse 2002;14:169–194.

    PubMed  Google Scholar 

  73. Gijs L, Gooren L. Hormonal and psychopharmacological interventions in the treatment of paraphilias: an update. J Sex Res 1996;33:273–290.

    Article  Google Scholar 

  74. Briken P, Hill A, Berner W. Pharmacotherapy of paraphilias with long-acting agonists of luteinizing hormone-releasing hormone: a systematic review. J Clin Psychiatry 2003;64:890–897.

    Article  CAS  PubMed  Google Scholar 

  75. Dickey R. The management of a case of treatment-resistant paraphilia with a long-acting LHRH agonist. Can J Psychiatry 1992;37:567–569.

    CAS  PubMed  Google Scholar 

  76. Rosler A, Witztum E. Treatment of men with paraphilia with a long-acting analogue of gonadotropin-releasing hormone. N Engl J Med 1998;338:416–422.

    Article  CAS  PubMed  Google Scholar 

  77. Abouesh A, Clayton A. Compulsive voyeurism and exhibitionism: a clinical response to paroxetine. Arch Sex Behav 1999;28:23–30.

    Article  CAS  PubMed  Google Scholar 

  78. Kafka MP. Sertraline pharmacotherapy for paraphilias and paraphilia-related disorders: an open trial. Ann Clin Psychiatry 1994;6:189–195.

    Article  CAS  PubMed  Google Scholar 

  79. Perilstein RD, Lipper S, Friedman LJ. Three cases of paraphilias responsive to fluoxetine treatment. J Clin Psychiatry 1991;52:169–170.

    CAS  PubMed  Google Scholar 

  80. Black DW, Kehrberg LL, Flumerfelt DL, Schlosser SS. Characteristics of 36 subjects reporting compulsive sexual behavior. Am J Psychiatry 1997;154:243–249.

    Article  CAS  PubMed  Google Scholar 

  81. Coleman E. Is your patient suffering from compulsive sexual behavior? Psychiatr Ann 1992;22:320–325.

    Article  Google Scholar 

  82. Kafka MP, Prentky RA. Compulsive sexual behavior characteristics. Am J Psychiatry 1997;154:1632.

    Article  CAS  PubMed  Google Scholar 

  83. Coleman E. Is your patient suffering from compulsive sexual behavior? Psychiatr Ann 1992;22:320–325.

    Article  Google Scholar 

  84. Kafka MP. The paraphilia-related disorders: A proposal for a unified classification of nonparaphilic hypersexuality disorders. Sexual Addiction and Compulsivity 2001;8:227–239.

    Article  Google Scholar 

  85. Kafka MP. Hypersexual desire in males: an operational definition and clinical implications for males with paraphilias and paraphilia-related disorders. Arch Sex Behav 1997;26:505–526.

    Article  CAS  PubMed  Google Scholar 

  86. Atwood JD, Gagnon J. Masturbatory behavior in college youth. J Sex Educ Ther 1987;13:35–42.

    Article  Google Scholar 

  87. Kinsey AC, Pomeroy WB, Martin CE. Sexual behavior in the human male. Philadelphia: W. B. Saunders Co.; 1948.

    Google Scholar 

  88. Kafka MP, Hennen J. The paraphilia-related disorders: an empirical investigation of nonparaphilic hypersexuality disorders in outpatient males. J Sex Marital Ther 1999;25:305–319.

    Article  CAS  PubMed  Google Scholar 

  89. Grant JE, Levine L, Kim D, Potenza MN. Impulse control disorders in adult psychiatric inpatients. Am J Psychiatry 2005;162:2184–2188.

    Article  PubMed  Google Scholar 

  90. Coleman E, Raymond N, McBean A. Assessment and treatment of compulsive sexual behavior. Minn Med 2003;86:42–47.

    PubMed  Google Scholar 

  91. Raymond NC, Coleman E, Miner MH. Psychiatric comorbidity and compulsive/impulsive traits in compulsive sexual behavior. Compr Psychiatry 2003;44:370–380.

    Article  PubMed  Google Scholar 

  92. Carnes P. Out of the Shadows: Understanding Sexual Addiction. Minneapolis, MN: CompCare Publications; 1983.

    Google Scholar 

  93. Goodman A. Diagnosis and treatment of sexual addiction. J Sex Marital Ther 1993;19:225–251.

    Article  CAS  PubMed  Google Scholar 

  94. Kafka MP. Paraphilia-related disorders--common, neglected, and misunderstood. Harv Rev Psychiatry 1994;2:39–40.

    Google Scholar 

  95. Schaffer SD, Zimmerman ML. The sexual addict: a challenge for the primary care provider. Nurse Pract 1990;15:25–26.

    Article  CAS  PubMed  Google Scholar 

  96. Barth RJ, Kinder BN. The mislabeling of sexual impulsivity. J Sex Marital Ther 1987;13:15–23.

    Article  CAS  PubMed  Google Scholar 

  97. Money J. Lovemaps: clinical concepts of sexual/erotic health and pathology, paraphilia, and gender transposition in childhood, adolescence, and maturity. New York: Irvington; 1986.

    Google Scholar 

  98. Kim SW. Opioid antagonists in the treatment of impulse-control disorders. J Clin Psychiatry 1998;59:159–164.

    Article  CAS  PubMed  Google Scholar 

  99. Raymond NC, Grant JE, Kim SW, Coleman E. Treatment of compulsive sexual behaviour with naltrexone and serotonin reuptake inhibitors: two case studies. Int Clin Psychopharmacol 2002;17:201–205.

    Article  CAS  PubMed  Google Scholar 

  100. Elliott ML, Biever LS. Head injury and sexual dysfunction. Brain Inj 1996;10:703–717.

    Article  CAS  PubMed  Google Scholar 

  101. Huws R, Shubsachs AP, Taylor PJ. Hypersexuality, fetishism and multiple sclerosis. Br J Psychiatry 1991;158:280–281.

    Article  CAS  PubMed  Google Scholar 

  102. Mendez MF, Chow T, Ringman J, Twitchell G, Hinkin CH. Pedophilia and temporal lobe disturbances. J Neuropsychiatry Clin Neurosci 2000;12:71–76.

    Article  CAS  PubMed  Google Scholar 

  103. Monga TN, Monga M, Raina MS, Hardjasudarma M. Hypersexuality in stroke. Arch Phys Med Rehabil 1986;67:415–417.

    CAS  PubMed  Google Scholar 

  104. Wainberg ML, Muench F, Morgenstern J, Hollander E, Irwin TW, Parsons JT, Allen A, O'Leary A. A double-blind study of citalopram versus placebo in the treatment of compulsive sexual behaviors in gay and bisexual men. J Clin Psychiatry 2006;67:1968–1973.

    Article  CAS  PubMed  Google Scholar 

  105. Bourgeois JA, Klein M. Risperidone and fluoxetine in the treatment of pedophilia with comorbid dysthymia. J Clin Psychopharmacol 1996;16:257–258.

    Article  CAS  PubMed  Google Scholar 

  106. Coleman E, Cesnik J, Moore A-M, Dwyer SM. An exploratory study of the role of psychotropic medications in the treatment of sex offenders. J Offend Rehab 1992;18:75–88.

    Article  Google Scholar 

  107. Emmanuel NP, Lydiard RB, Ballenger JC. Fluoxetine treatment of voyeurism. Am J Psychiatry 1991;148:950.

    CAS  PubMed  Google Scholar 

  108. Fedoroff JP. Serotenergic drugs treatment of deviant sexual interests. Ann Sex Res 1993;6:105–121.

    Article  Google Scholar 

  109. Kafka MP. Successful antidepressant treatment of nonparaphilic sexual addictions and paraphilias in men. J Clin Psychiatry 1991;52:60–65.

    CAS  PubMed  Google Scholar 

  110. Kafka MP, Coleman E. Serotonin and paraphilias: the convergence of mood, impulse and compulsive disorders. J Clin Psychopharmacol 1991;11:223–224.

    Article  CAS  PubMed  Google Scholar 

  111. Kafka MP, Prentky R. Fluoxetine treatment of nonparaphilic sexual addictions and paraphilias in men. J Clin Psychiatry 1992;53:351–358.

    CAS  PubMed  Google Scholar 

  112. Pearson HJ. Paraphilias, impulse control, and serotonin. J Clin Psychopharmacol 1990;10:233.

    Article  CAS  PubMed  Google Scholar 

  113. Stein DJ, Hollander E, Anthony DT, Schneier FR, Fallon BA, Liebowitz MR, Klein DF. Serotonergic medications for sexual obsessions, sexual addictions, and paraphilias. J Clin Psychiatry 1992;53:267–271.

    CAS  PubMed  Google Scholar 

  114. Kruesi MJ, Fine S, Valladares L, Phillips RA Jr, Rapoport JL. Paraphilias: a double-blind crossover comparison of clomipramine versus desipramine. Arch Sex Behav 1992;21:587–593.

    Article  CAS  PubMed  Google Scholar 

  115. Fedoroff JP. Buspirone hydrochloride in the treatment of an atypical paraphilia. Arch Sex Behav 1992;21:401–406.

    Article  CAS  PubMed  Google Scholar 

  116. Fedoroff JP. Buspirone hydrochloride in the treatment of transvestic fetishism. J Clin Psychiatry 1988;49:408–409.

    CAS  PubMed  Google Scholar 

  117. Coleman E, Gratzer T, Nesvacil L, Raymond NC. Nefazodone and the treatment of nonparaphilic compulsive sexual behavior: a retrospective study. J Clin Psychiatry 2000;61:282–284.

    CAS  PubMed  Google Scholar 

  118. Cesnik JA, Coleman E. Use of lithium carbonate in the treatment of autoerotic asphyxia. Am J Psychother 1989;43:277–286.

    CAS  PubMed  Google Scholar 

  119. Ward NG. Successful lithium treatment of transvestism associated with manic-depression. J Nerv Ment Dis 1975;161:204–206.

    Article  CAS  PubMed  Google Scholar 

  120. Grant JE, Kim SW. Gender differences in pathological gamblers seeking medication treatment. Compr Psychiatry 2002;43:56–62.

    Article  PubMed  Google Scholar 

  121. Kim SW, Grant JE, Yoon G, Williams KA, Remmel RP. Safety of high-dose naltrexone treatment: hepatic transaminase profiles among outpatients. Clin Neuropharmacol 2006;29:77–79.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Jon E. Grant M.D., J.D., M.P.H. .

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Grant, J.E., Raymond, N.C. (2016). Sexual Disorders: Dysfunction, Gender Identity and Paraphilias. In: Fatemi, S., Clayton, P. (eds) The Medical Basis of Psychiatry. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2528-5_16

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