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Neurointervention and the Endocrinologist: Inferior Petrosal Sinus Sampling

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Neurointervention in the Medical Specialties

Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

Inferior petrosal sinus sampling (IPSS) is a major advance in the medical management of Cushing’s syndrome (CS). Using this selective catheterization technique, it was possible to sample ACTH output centrally and peripherally and later even lateralize ACTH production. IPSS has continued to gain wide acceptance and now it is internationally considered the gold standard for diagnosing CD. This chapter will explain IPSS including its applications, limitations, techniques, complications, and cost-effectiveness. It behooves all physicians involved in the medical management of CS to better understand this procedure.

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Authors and Affiliations

  1. Department of Neurology, University of South Carolina School of Medicine, 8 Medical Park, Suite 420, SC, 29203, Columbia

    Sonal Mehta M.D. (Assistant Professor)

  2. Department of Neurology and Psychiatry, Saint Louis University, 1438 S. Grand Blvd, St. Louis, MO, 63104, USA

    Randall C. Edgell M.D.

  3. Division of Endocrinology, Department of Internal Medicine, Saint Louis University, St. Louis, MO, USA

    George T. Griffing M.D.

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  1. Sonal Mehta M.D.
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  2. Randall C. Edgell M.D.
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  3. George T. Griffing M.D.
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Correspondence to Sonal Mehta M.D. .

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  1. Department of Neurology and Psychiatry, Saint Louis University, St. Louis, Missouri, USA

    Randall C. Edgell

  2. Department of Neurology, University of Texas Health Science Center, UT-HEALTH, Houston, Texas, USA

    Sean I. Savitz

  3. Department of Neurosurgery, Albany Medical Center, Albany, New York, USA

    John Dalfino

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Mehta, S., Edgell, R.C., Griffing, G.T. (2015). Neurointervention and the Endocrinologist: Inferior Petrosal Sinus Sampling. In: Edgell, R., Savitz, S., Dalfino, J. (eds) Neurointervention in the Medical Specialties. Current Clinical Neurology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1942-0_17

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