Abstract
Isoleucine (Ile) is an essential branched-chain amino acid that plays several roles in the body. Ile has been shown to increase free fatty acid oxidation in skeletal muscle and liver. In addition, Ile prevents the accumulation of tissue triglycerides and up-regulates the expression of peroxisome proliferator-activated receptor (PPAR)-alpha and uncoupling protein (UCP). In the present chapter, I have focused on the relationship between Ile, PPAR and UCP.
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Masaki, T. (2015). Isoleucine, PPAR and Uncoupling Proteins. In: Rajendram, R., Preedy, V., Patel, V. (eds) Branched Chain Amino Acids in Clinical Nutrition. Nutrition and Health. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1923-9_4
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DOI: https://doi.org/10.1007/978-1-4939-1923-9_4
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