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Chorioamnionitis and Oxidative Stress: New Ideas from Experimental Models

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Perinatal and Prenatal Disorders

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Abstract

Chorioamnionitis is commonly associated with preterm labor and delivery. The infection in chorioamnionitis is mainly in the amniotic compartment. Chorioamnionitis is however a risk factor for adverse outcomes after preterm birth such as bronchopulmonary dysplasia, necrotizing enterocolitis, and injury to the brain’s white matter. In this chapter, we discuss the contribution of oxidative stress from chorioamnionitis to fetal organ injury.

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Authors and Affiliations

  1. Department of Pediatrics, School of Oncology and Developmental Biology, School of Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands

    Boris W. Kramer M.D., Ph.D.

  2. Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA

    Suhas G. Kallapur & Alan H. Jobe

Authors
  1. Boris W. Kramer M.D., Ph.D.
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  2. Suhas G. Kallapur
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  3. Alan H. Jobe
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Corresponding author

Correspondence to Boris W. Kramer M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. University of Penn, Perelman Sch of Med Professor of Pediatrics, Children's Hospital of Philadelphia Division of Neonatology, Philadelphia, Pennsylvania, USA

    Phyllis A. Dennery

  2. Lab of Oxidative Stress Policlinico “Le Scotte“, University of Siena Dept of Peds, Obstetrics & Reprod Med, Siena, Italy

    Giuseppe Buonocore

  3. Department of Pediatrics, University of Oslo Faculty of Medicine Rikshospitalit Medical Center, Oslo, Norway

    Ola Didrik Saugstad

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Kramer, B.W., Kallapur, S.G., Jobe, A.H. (2014). Chorioamnionitis and Oxidative Stress: New Ideas from Experimental Models. In: Dennery, P., Buonocore, G., Saugstad, O. (eds) Perinatal and Prenatal Disorders. Oxidative Stress in Applied Basic Research and Clinical Practice. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1405-0_2

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