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Sepsis and Nutrition

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Surgical Metabolism

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Abstract

Sepsis continues to be a common and serious problem. As the population ages, the incidence of sepsis in the United States continues to climb. It is estimated that in the United States, there are greater than 1.1 million cases of sepsis per year at an annual cost of $24.3 billion. Sepsis remains the leading cause of death in non-cardiac intensive care units (ICUs). In spite of extensive research, sepsis related mortality remains prohibitively high. In recent years, multiple professional organizations have developed evidence-based guidelines for the management of sepsis. The intent of such guidelines is to improve patient outcomes by aiding clinicians in the delivery of evidence-based care. Providing adequate nutritional support of critically ill patients, including those with sepsis, is a key factor in improving patient outcomes. The provision of early nutritional support via the enteral route can attenuate the metabolic response to stress, favorably modulate the host’s immune response, reduce the risk nosocomial infections, and reduce the risk organ dysfunctions associated with critical illness. In this chapter, we will review the current literature as it relates to the nutritional support of critically ill patients with sepsis.

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Authors and Affiliations

  1. Department of Surgery, Division of Acute Care Surgery, The University of Texas Health Science Center at Houston, Memorial Hermann Hospital, 6431 Fannin Street, MSB 4.292, Houston, TX, 77030, USA

    Laura J. Moore MD, FACS

  2. Division of Surgical Critical Care & Acute Care Surgery, Department of Surgery, University of Florida, 1600 Southwest Archer Road, Gainesville, FL, USA

    Frederick A. Moore MD, FACS, MCCM

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  1. Laura J. Moore MD, FACS
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  2. Frederick A. Moore MD, FACS, MCCM
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Correspondence to Laura J. Moore MD, FACS .

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Editors and Affiliations

  1. Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA

    Kimberly A. Davis

  2. Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut, USA

    Stanley H. Rosenbaum

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Moore, L.J., Moore, F.A. (2014). Sepsis and Nutrition. In: Davis, K., Rosenbaum, S. (eds) Surgical Metabolism. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1121-9_9

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