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Obesity and Exercise

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Advances in Cancer Survivorship Management

Part of the book series: MD Anderson Cancer Care Series ((MDCCS))

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Abstract

Physical inactivity and obesity are common problems among cancer survivors. Physical inactivity and obesity are risk factors for several forms of cancer, and weight gain and declines in physical activity often occur after a cancer diagnosis and during treatment. Low physical activity has been shown to lead to poor outcomes in breast and colon cancer survivors, and exercise interventions for survivors improve physical functioning and quality of life in several domains. Some evidence suggests that weight changes in breast cancer survivors may affect disease-free survival, but the evidence is conflicting on this point. Obesity can decrease cancer survivors’ quality of life, as well as increase their risks for comorbid health problems. The American Cancer Society has recently published nutrition, physical activity, and weight management recommendations for cancer survivors. Survivorship care should include giving survivors access to this information. In addition, encouraging survivors to adopt evidence-based behavioral strategies such as setting goals, monitoring themselves, changing their environment, and seeking social support can facilitate healthful behavior changes.

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Suggested Readings

  • Bacon L, Stern JS, Van Loan MD, Keim NL. Size acceptance and intuitive eating improve health for obese, female chronic dieters. J Am Diet Assoc 2005;105(6):929–936.

    Article  PubMed  Google Scholar 

  • Ballard-Barbash R, Friedenreich CM, Courneya KS, Siddiqi SM, McTiernan A, Alfano CM. Physical activity, biomarkers, and disease outcomes in cancer survivors: a systematic review. J Natl Cancer Inst 2012;104(11):815–840.

    Article  PubMed  PubMed Central  Google Scholar 

  • Basen-Engquist K, Perkins H, Carmack C, et al. Test of weight gain prevention intervention in stage II and III breast cancer patients receiving neoadjuvant chemotherapy. Cancer Epidemiol Biomarkers Prev 2010;19(3):895–896.

    Article  Google Scholar 

  • Basen-Engquist K, Scruggs S, Jhingran A, et al. Physical activity and obesity in endometrial cancer survivors: associations with pain, fatigue, and physical functioning. Am J Obstet Gynecol 2009;200(3):288 e281–288.

    Google Scholar 

  • Basen-Engquist K, Taylor CC, Rosenblum C, et al. Randomized pilot test of a lifestyle physical activity intervention for breast cancer survivors. Patient Educ Couns 2006;64(1–3):225–234.

    Article  PubMed  Google Scholar 

  • Bravata DM, Smith-Spangler C, Sundaram V, et al. Using pedometers to increase physical activity and improve health: a systematic review. JAMA 2007;298(19):2296–2304.

    Article  PubMed  CAS  Google Scholar 

  • Caan BJ, Emond JA, Natarajan L, et al. Post-diagnosis weight gain and breast cancer recurrence in women with early stage breast cancer. Breast Cancer Res Treat 2006;99(1):47–57.

    Article  PubMed  Google Scholar 

  • Caan BJ, Kwan ML, Hartzell G, et al. Pre-diagnosis body mass index, post-diagnosis weight change, and prognosis among women with early stage breast cancer. Cancer Causes Control 2008;19(10):1319–1328.

    Article  PubMed  PubMed Central  Google Scholar 

  • Chlebowski RT, Blackburn GL, Thomson CA, et al. Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women’s Intervention Nutrition Study. J Natl Cancer Inst 2006;98(24):1767–1776.

    Article  PubMed  Google Scholar 

  • Demark-Wahnefried W, Clipp EC, Lipkus IM, et al. Main outcomes of the FRESH START trial: a sequentially tailored, diet and exercise mailed print intervention among breast and prostate cancer survivors. J Clin Oncol 2007;25(19):2709–2718.

    Article  PubMed  Google Scholar 

  • Demark-Wahnefried W, Platz EA, Ligibel JA, et al. The role of obesity in cancer survival and recurrence. Cancer Epidemiol Biomarkers Prev 2012;21(8):1244–1259.

    Article  PubMed  PubMed Central  Google Scholar 

  • Garmey EG, Liu Q, Sklar CA, et al. Longitudinal changes in obesity and body mass index among adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol 2008;26(28):4639–4645.

    Article  PubMed  PubMed Central  Google Scholar 

  • Jones LW, Courneya KS, Fairey AS, Mackey JR. Effects of an oncologist’s recommendation to exercise on self-reported exercise behavior in newly diagnosed breast cancer survivors: a single-blind, randomized controlled trial. Ann Behav Med 2004;28(2):105–113.

    Article  PubMed  Google Scholar 

  • Kim HS, Moreira DM, Smith MR, et al. A natural history of weight change in men with prostate cancer on androgen-deprivation therapy (ADT): results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. BJU Int 2010;107(6):924–928.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kroenke CH, Chen WY, Rosner B, Holmes MD. Weight, weight gain, and survival after breast cancer diagnosis. J Clin Oncol 2005;23(7):1370–1378.

    Article  PubMed  Google Scholar 

  • Lustig RH, Post SR, Srivannaboon K, et al. Risk factors for the development of obesity in children surviving brain tumors. J Clin Endocrinol Metab 2003;88(2):611–616.

    Article  PubMed  CAS  Google Scholar 

  • Meyerhardt JA, Heseltine D, Niedzwiecki D, et al. Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol 2006;24:3535–3541.

    Article  PubMed  Google Scholar 

  • Meyerhardt JA, Ogino S, Kirkner GJ, et al. Interaction of molecular markers and physical activity on mortality in patients with colon cancer. Clin Cancer Res 2009;15(18):5931–5936.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Mishra SI, Scherer RW, Geigle PM, et al. Exercise interventions on health-related quality of life for cancer survivors. Cochrane Database Syst Rev 2012;8:CD007566.

    PubMed  Google Scholar 

  • Morey MC, Snyder DC, Sloane R, et al. Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized controlled trial. JAMA 2009;301(18):1883–1891.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Morikawa T, Kuchiba A, Yamauchi M, et al. Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer. JAMA 2011;305(16):1685–1694.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Mosher CE, Sloane R, Morey MC, et al. Associations between lifestyle factors and quality of life among older long-term breast, prostate, and colorectal cancer survivors. Cancer 2009;115(17):4001–4009.

    Article  PubMed  PubMed Central  Google Scholar 

  • Nichols HB, Trentham-Dietz A, Egan KM, et al. Body mass index before and after breast cancer diagnosis: associations with all-cause, breast cancer, and cardiovascular disease mortality. Cancer Epidemiol Biomarkers Prev 2009;18(5):1403–1409.

    Article  PubMed  PubMed Central  Google Scholar 

  • Pierce JP, Natarajan L, Caan BJ, et al. Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women’s Healthy Eating and Living (WHEL) randomized trial. JAMA 2007a;298(3):289–298.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  • Pierce JP, Stefanick ML, Flatt SW, et al. Greater survival after breast cancer in physically active women with high vegetable-fruit intake regardless of obesity. J Clin Oncol 2007b;25(17):2345–2351.

    Article  PubMed  PubMed Central  Google Scholar 

  • Pinto BM, Frierson GM, Rabin C, Trunzo JJ, Marcus BH. Home-based physical activity intervention for breast cancer patients. J Clin Oncol 2005;23(15):3577–3587.

    Article  PubMed  Google Scholar 

  • Rock CL, Doyle C, Demark-Wahnefried W, et al. Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin 2012;62(4):243–274.

    Article  PubMed  Google Scholar 

  • Sagstuen H, Aass N, Fossa SD, et al. Blood pressure and body mass index in long-term survivors of testicular cancer. J Clin Oncol 2005;23(22):4980–4990.

    Article  PubMed  CAS  Google Scholar 

  • Schmitz KH, Ahmed RL, Troxel A, et al. Weight lifting in women with breast-cancer-related lymphedema. N Engl J Med 2009;361(7):664–673.

    Article  PubMed  CAS  Google Scholar 

  • Schmitz KH, Ahmed RL, Troxel AB, et al. Weight lifting for women at risk for breast cancer-related lymphedema: a randomized trial. JAMA 2010;304(24):2699–2705.

    Article  PubMed  CAS  Google Scholar 

  • Speck RM, Courneya KS, Masse LC, Duval S, Schmitz KH. An update of controlled physical activity trials in cancer survivors: a systematic review and meta-analysis. J Cancer Surv 2010;4(2):87–100.

    Article  Google Scholar 

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© 2015 The University of Texas M. D. Anderson Cancer Center

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Basen-Engquist, K. (2015). Obesity and Exercise. In: Foxhall, L., Rodriguez, M. (eds) Advances in Cancer Survivorship Management. MD Anderson Cancer Care Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0986-5_16

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  • DOI: https://doi.org/10.1007/978-1-4939-0986-5_16

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-0985-8

  • Online ISBN: 978-1-4939-0986-5

  • eBook Packages: MedicineMedicine (R0)

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