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Gastritis, Esophagitis and Peptic Ulcer Disease

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Family Medicine

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Abstract

Gastritis, esophagitis, and peptic ulcer disease (PUD) present commonly with epigastric pain or dyspepsia. Dyspepsia refers to upper abdominal pain or discomfort and may be associated with fullness, belching, bloating, heartburn, food intolerance, nausea, or vomiting. Dyspepsia is a common problem. Most patients have no organic cause and are defined as having functional dyspepsia.

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References

  1. Moayyedi PM, Lacy BE, Andrews CN, Enns RA, Howden CW, Vakil N. ACG and CAG linical guideline: management of dyspepsia. Am J Gastroenterol. 2017;112:988–1013.

    Article  CAS  Google Scholar 

  2. Drossman DA, Hasler WL. Rome IV-functional GI disorders: disorders of gut-brain interaction. Gastroenterology. 2016 May;150(6):1257–61.

    Article  Google Scholar 

  3. Mounsey A, Barzin A, Rietz A. Functional dyspepsia: evaluation and management. Am Fam Physician. 2020;101(2):84–8.

    PubMed  Google Scholar 

  4. El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014;63:871–80.

    Article  Google Scholar 

  5. Sandlers RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology. 2002;122(5):1500–11.

    Article  Google Scholar 

  6. Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol. 2013;108:308–28.

    Article  Google Scholar 

  7. Gikas A, Triantafillidis JK. The role of primary care physicians in early diagnosis and treatment of chronic gastrointestinal diseases. Int J Gen Med. 2014;7:159–73.

    Article  Google Scholar 

  8. Ling-Zhi Y, Ping Y, Gang-Shi W, et al. Lifestyle intervention for gastroesophageal reflux disease: a national multicenter survey of lifestyle factor effects on gastroesophageal reflux disease in China. Ther Adv Gastroenterol. 2019;12:1–12.

    Google Scholar 

  9. Sigterman KE, van Pinxteren B, Bonis PA, et al. Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database Syst Rev. 2013;2013(5):CD002095.

    PubMed Central  Google Scholar 

  10. Poly TN, Islam MM, Yang HC, Wu CC, Li YJ. Proton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies. Osteoporos Int. 2019 Jan;30(1):103–14.

    Article  CAS  Google Scholar 

  11. Jaynes M, Kumar A. The risks of long term proton pump inhibitors: a critical review. Ther Adv Drug Saf. 2019;10:1–13.

    Article  Google Scholar 

  12. Wileman SM, McCann S, Grant AM, Krukowski ZH, Bruce J. Medical versus surgical management for gastro-oesophageal reflux disease (GORD) in adults. Cochrane Database Syst Rev. 2010;(3):CD003243. https://doi.org/10.1002/14651858.CD003243.pub2.

  13. Fashner J, Gitu AC. Diagnosis and treatment of peptic ulcer disease and H. pylori infection. Am Fam Physician. 2015;91:236–42.

    PubMed  Google Scholar 

  14. Ford AC, Gurusamy KS, Delaney B, Forman D, Moayyedi P. Eradication therapy for peptic ulcer disease in Helicobacter pylori-positive people. Cochrane Database Syst Rev. 2016;2016(4):CD003840.

    PubMed Central  Google Scholar 

  15. Heung Up K. Diagnostic and treatment approaches for refractory peptic ulcers. Clin Endosc. 2015;48(4):285–90.

    Article  Google Scholar 

  16. Rantanen T, Udd M, Honkanen T, et al. Effect of omeprazole dose, nonsteroidal anti-inflammatory agents, and smoking on repair mechanisms in acute peptic ulcer bleeding. Dig Dis Sci. 2014;59:2666–74.

    Article  CAS  Google Scholar 

  17. Laine L, Jensen DM. Management of patients with ulcer bleeding. Am J Gastroenterol. 2012;107:345–60. https://doi.org/10.1038/ajg.2011.480. Published online 7 Feb 2012

    Article  CAS  PubMed  Google Scholar 

  18. Rockey DC, Ahn C, de Melo SW Jr. Randomized pragmatic trial of nasogastric tube placement in patients with upper gastrointestinal tract bleeding. J Investig Med. 2017;65:759.

    Article  Google Scholar 

  19. Stanley AJ, Laine L. Management of acute upper gastrointestinal bleeding. BMJ. 2019;364:l536.

    Article  Google Scholar 

  20. Wilkins T, Wheeler B, Carpenter C. Upper gastrointestinal bleeding in adults: evaluation and management. Am Fam Physician. 2020 Mar 1;101(5):294–300.

    PubMed  Google Scholar 

  21. Smith A, Baumgartner K, Bositis C. Cirrhosis: diagnosis and management. Am Fam Physician. 2019 Dec 15;100(12):759–70.

    PubMed  Google Scholar 

  22. Charalampakis N, Economopoulou P, Kotsantis I, et al. Medical management of gastric cancer: a 2017 update. Cancer Med. 2018 Jan;7(1):123–33.

    Article  Google Scholar 

  23. Cats A, Jansen EP, van Grieken NC, et al. Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomized phase 3 trial. Lancet Oncol. 2018;19:616–28.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Family and Community Medicine, Penn State University College of Medicine, Hershey, PA, USA

    Jennifer L. Grana, Christopher R. Heron & Alan M. Adelman

Authors
  1. Jennifer L. Grana
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  2. Christopher R. Heron
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  3. Alan M. Adelman
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Corresponding author

Correspondence to Alan M. Adelman .

Editor information

Editors and Affiliations

  1. Department of Family Medicine, University of Nebraska, Omaha, NE, USA

    Paul Paulman

  2. Department of Family and Community Medicine, Eastern Virginia Medical School, Norfolk, VA, USA

    Robert B. Taylor

  3. Department of Family Medicine, University of Nebraska Medical Center, Omaha, NE, USA

    Audrey A. Paulman

  4. Department of Family Medicine, Creighton University, Omaha, NE, USA

    Laeth S. Nasir

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Grana, J.L., Heron, C.R., Adelman, A.M. (2020). Gastritis, Esophagitis and Peptic Ulcer Disease. In: Paulman, P., Taylor, R.B., Paulman, A.A., Nasir, L.S. (eds) Family Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0779-3_94-2

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  • DOI: https://doi.org/10.1007/978-1-4939-0779-3_94-2

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-0779-3

  • Online ISBN: 978-1-4939-0779-3

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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Chapter history

  1. Latest

    Gastritis, Esophagitis and Peptic Ulcer Disease
    Published:
    07 October 2020

    DOI: https://doi.org/10.1007/978-1-4939-0779-3_94-2

  2. Original

    Gastritis, Esophagitis, and Peptic Ulcer Disease
    Published:
    24 April 2015

    DOI: https://doi.org/10.1007/978-1-4939-0779-3_94-1

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