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The Prevention and Treatment of Coronary Artery Disease in Kidney Transplant Recipients

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Abstract

Cardiovascular disease (CVD) is the leading cause of death amongst renal transplant recipients. Pre-transplant evaluation of cardiovascular risk in potential recipients is the standard for most transplant centers, though the method of evaluation varies. Risk factors for CVD are prevalent amongst patients with chronic kidney disease and include diabetes, hyperlipidemia, hypertension, and smoking.

Management of the risk factors that contribute to CVD is suboptimal in the post-transplant population. Not only are the pre-transplant cardiovascular risk factors often still present, but de novo factors such as post-transplant diabetes, drug effects on blood pressure and lipids, and weight gain can exacerbate the already increased cardiovascular risk. Hypertension and hyperlipidemia should be aggressively managed. The recidivism rate for smoking is high and underappreciated by the medical community. Diet, exercise, and weight gains need to be addressed at each clinic visit.

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  1. University of California, Davis, 2233 Stockton Blvd, Housestaff Bldg, Room 2011, Sacramento, CA, 95817, USA

    Deborah B. Adey

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  1. Department of Nephrology, University of Maryland, Baltimore, Maryland, USA

    Matthew R. Weir

  2. Department of Medicine, Section of Nephrology, University of Illinois, Berwyn, Illinois, USA

    Edgar V. Lerma

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Adey, D.B. (2014). The Prevention and Treatment of Coronary Artery Disease in Kidney Transplant Recipients. In: Weir, M., Lerma, E. (eds) Kidney Transplantation. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0342-9_18

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