Abstract
All nuclear processes, including transcription by RNA polymerase II, take place in the context of the higher-order packaging of DNA into chromatin. Controlled gene expression requires first unimpeded access to the DNA by the transcriptional machinery and subsequent reformation of DNA into chromatin to avoid aberrant transcription. We will discuss the regulatory mechanisms that promote and limit RNA polymerase II transcription in cells.
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Smolle, M., Venkatesh, S. (2014). Transcription Through Chromatin. In: Workman, J., Abmayr, S. (eds) Fundamentals of Chromatin. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8624-4_11
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