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Use of Ethanol Lock Therapy for Children with Intestinal Failure on Long-Term Parenteral Nutrition

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Diet and Nutrition in Critical Care

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Abstract

Children with intestinal failure are often dependent on long-term central venous catheters for delivery of all or a portion of their fluid and caloric requirements. Unfortunately, they are at high risk for catheter-associated complications, most commonly infection. Catheter-related bloodstream infections (CRBSI) can be difficult to treat and can lead to systemic sepsis and critical illness in this patient population. This chapter discusses the role for ethanol lock therapy (ELT) in both the prevention and treatment of CRBSI in children with intestinal failure. The safety and efficacy of this therapy is discussed and the details for use in the pediatric population are provided.

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Abbreviations

CRBSI:

Catheter-related bloodstream infection

CVC:

Central venous catheter

ELT:

Ethanol lock therapy

IF:

Intestinal failure

IFALD:

Intestinal failure-associated liver disease

PN:

Parenteral nutrition

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Author information

Authors and Affiliations

  1. Division of Pediatric Surgery, University of Texas Shouthwestern, Children’s Health, Dallas, TX, USA

    Hannah G. Piper

  2. Group for Improvement of Intestinal Function and Treatment (GIFT), Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada

    Paul W. Wales

Authors
  1. Hannah G. Piper
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  2. Paul W. Wales
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Corresponding author

Correspondence to Paul W. Wales .

Editor information

Editors and Affiliations

  1. Department of Nutrition, King's College London, London, United Kingdom

    Rajkumar Rajendram

  2. School of Medicine, King's College London, London, United Kingdom

    Victor R. Preedy

  3. Department of Biomedical Sciences, University of Westminster, London, United Kingdom

    Vinood B. Patel

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Piper, H.G., Wales, P.W. (2014). Use of Ethanol Lock Therapy for Children with Intestinal Failure on Long-Term Parenteral Nutrition. In: Rajendram, R., Preedy, V., Patel, V. (eds) Diet and Nutrition in Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8503-2_15-1

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  • DOI: https://doi.org/10.1007/978-1-4614-8503-2_15-1

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  • Online ISBN: 978-1-4614-8503-2

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