Abstract
Image-guided liver biopsy is among the most common procedures performed by the interventional radiologist. Non-focal liver biopsy is the gold standard for the diagnosis and staging of diffuse parenchymal disease and may be performed using direct percutaneous or transjugular approaches. Sonography is the mainstay of imaging guidance for direct percutaneous non-focal liver biopsy. Given the slightly inferior quality of specimens obtained by the transjugular liver biopsy, it is generally reserved for specific circumstances, including coagulopathy, which may otherwise increase the risk of direct percutaneous technique, as well as when hepatic venous pressure gradient measurements are required. When focal hepatic lesions are encountered which do not demonstrate definite benign imaging features, image-guided biopsy can be effective in establishing a diagnosis and may be guided by US, CT, or MRI. In addition, although a majority of endobiliary work is performed by gastroenterologists, endobiliary biopsy via percutaneous transhepatic tracts may be an important means of evaluating biliary strictures when the endoscopic route is impossible.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Hahn PF, Gervais DA, O’Neill MJ, Mueller PR. Nonvascular interventional procedures: analysis of a 10-year database containing more than 10,000 cases. Radiology. 2001;220:730–6.
Flemming JA, Hurlbut DJ, Mussari B, Hookey LC. Liver biopsies for chronic hepatitis C: should nonultrasound-guided biopsies be abandoned? Can J Gastroenterol. 2009;23:425–30.
Lindor KD, Bru C, Jorgensen RA, et al. The role of ultrasonography and automatic-needle biopsy in outpatient percutaneous liver biopsy. Hepatology. 1996;23:1079–83.
Farrell RJ, Smiddy PF, Pilkington RM, et al. Guided versus blind liver biopsy for chronic hepatitis C: clinical benefits and costs. J Hepatol. 1999;30:580–7.
Pasha T, Gabriel S, Therneau T, Dickson ER, Lindor KD. Cost effectiveness of ultrasound-guided liver biopsy. Hepatology. 1998;27:1220–6.
Kaye R, Sane S, Towbin RB. Pediatric intervention: an update—Part II. J Vasc Interv Radiol. 2000;11:807–22.
Bromley PJ, Kaufman JA. In: Kaufman JA, Lee MJ, editors. Vascular and interventional radiology: the requisites. Philadelphia: Mosby; 2004. p. 377–406.
Kalambokis G, Manousou P, Vibhakorn S, et al. Transjugular liver biopsy—indications, adequacy, quality of specimens, and complications—a systematic review. J Hepatol. 2007;47:284–94.
Mammen T, Keshava SN, Eapen CE, et al. Transjugular liver biopsy: a retrospective analysis of 601 cases. J Vasc Interv Radiol. 2008;19:351–8.
Kinney TB. Percutaneous biopsy. In: Valji K, editor. Vascular and interventional radiology. 2nd ed. Philadelphia: Saunders Elsevier; 2006. p. 495–515.
Withers CE, Casola G, Herba MJ, et al. Intravascular tumors: transvenous biopsy. Radiology. 1988;167:713–15.
Bravo AA, Sheth SG, Chopra S. Liver biopsy. N Engl J Med. 2001;344:495–500.
Dotter CT. Catheter biopsy. Experimental technique for transvenous liver biopsy. Radiology. 1964;82:312–14.
Guido M, Rugge M. Liver biopsy sampling in chronic viral hepatitis. Semin Liver Dis. 2004;24:89–97.
Sheela H, Seela S, Caldwell C, Boyer JL, Jain D. Liver biopsy: evolving role in the new millennium. J Clin Gastroenterol. 2005;39:603–10.
Little AF, Ferris JV, Dodd III GD, Baron RL. Image-guided percutaneous hepatic biopsy: effect of ascites on the complication rate. Radiology. 1996;199:79–83.
Murphy FB, Barefield KP, Steinberg HV, Bernardino ME. CT- or sonographically-guided biopsy of the liver in the presence of ascites: frequency of complications. Am J Roentgenol. 1988;151:485–6.
Lee MJ. Image-guided percutaneous biopsy. In: Kaufman JA, Lee MJ, editors. Vascular and interventional radiology: the requisites. Philadelphia: Mosby; 2004. p. 469–88.
Paulson EK, Sheafor DH, Enterline DS, McAdams HP, Yoshizumi TT. CT fluoroscopy-guided interventional procedures: techniques and radiation dose to radiologists. Radiology. 2001;220:161–7.
Silverman SG, Tuncali K, Adams DF, Nawfel RD, Zou KH, Judy PF. CT fluoroscopy-guided abdominal interventions: techniques, results, and radiation exposure. Radiology. 1999;212:673–81.
Gupta S. New techniques in image-guided percutaneous biopsy. Cardiovasc Intervent Radiol. 2004;27:91–104.
Gervais DA, Gazelle GS, Lu DSK, Hahn PF, Mueller PR. Percutaneous transpulmonary CT-guided liver biopsy: a safe and technically easy approach for lesions located near the diaphragm. Am J Roentgenol. 1996;167:482–3.
Westcott J. Percutaneous transthoracic needle biopsy. Radiology. 1988;169:593–601.
Sinner W. Complications of percutaneous transthoracic needle aspiration biopsy. Acta Radiol. 1976;17:813–28.
Berquist T, Bailey P, Cortese D, Miller W. Transthoracic needle biopsy: accuracy and complications in relation to location and type of lesion. Mayo Clin Proc. 1980;55:475–81.
Adam G, Bucker A, Nolte-Ernsting C, Tacke J, Gunther RW. Interventional MR imaging: percutaneous abdominal and skeletal biopsies and drainages of the abdomen. Eur Radiol. 1999;9:1471–8.
Stattaus J, Maderwald S, Baba HA, et al. MR-guided liver biopsy within a short, wide-bore 1.5 Tesla MR system. Eur Radiol. 2008;18:2865–73.
Durek JL, Lewin JS, Wendt M, Petersilge C. Remember true-FISP? A high SNR, near 1 second imaging method for T2-like contrast interventional MRI at 0.2 T. J Magn Reson Imaging. 1999;8:203–8.
Hopper KD, Abendroth CS, Sturtz KW, Matthews KW, Stevens LA, Shirk SJ. Automated biopsy devices: a blinded evaluation. Radiology. 1993;187:653–60.
Hopper KD, Abendroth CS, Sturtz KW, Matthews YL, Shirk SJ, Stevens LA. Blinded comparison of biopsy needles and automated devices in vitro. 1. Biopsy of diffuse hepatic disease. Am J Roentgenol. 1993;161:1293–7.
Haaga JR, LiPuma JP, Bryan PJ, Balsara VJ, Cohen AM. Clinical comparison of small- and large- caliber cutting needles for biopsy. Radiology. 1983;146:665–7.
Erwin BC, Brynes RK, Chan WC, et al. Percutaneous needle biopsy in the diagnosis and classification of lymphoma. Cancer. 1986;57:1074–8.
Welch TJ, Sheedy 2nd PF, Johnson CD, Johnson CM, Stephens DH. CT-guided biopsy: prospective analysis of 1,000 procedures. Radiology. 1989;171:493–6.
Hatfield MK, Beres RA, Sane SS, Zaleski GX. Percutaneous imaging-guided solid organ core needle biopsy: coaxial versus noncoaxial method. Am J Roentgenol. 2008;190:413–17.
Appelbaum L, Kane RA, Kruskal JB, Romero J, Sosna J. Focal hepatic lesions: US-guided biopsy—lesions from review of cytologic and pathologic examination. Radiology. 2008;250:453–8.
Moulton JS, Moore PT. Coaxial percutaneous biopsy technique with automated biopsy devices: value in improving accuracy and negative predictive value. Radiology. 1993;186:515–22.
Tan KT, Rajan DK, Kachura JR, et al. Pain after percutaneous liver biopsy for diffuse hepatic disease: a randomized trial comparing subcostal and intercostals approaches. J Vasc Interv Radiol. 2005;16:1215–19.
Smith EH. Complications of percutaneous abdominal fine-needle biopsy. Radiology. 1991;178:253–8.
Silverman SG. Percutaneous image-guided abdominal biopsy. In: Kandarpa K, Aruny JE, editors. Handbook of interventional radiologic procedures. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2002. p. 342–53.
Pietrobattista A, Fruwirth R, Natali G, et al. Is juvenile liver biopsy unsafe? Putting an end to a common misapprehension. Pediatr Radiol. 2009. Published online ahead of print.
Brown DB, Gonsalves CF. Percutaneous biopsy before interventional oncologic therapy: current status. J Vasc Interv Radiol. 2008;19:973–9.
Cardella JF, Bakal CW, Bertino RE, et al. Quality improvement guidelines for image-guided percutaneous biopsy in adults. J Vasc Interv Radiol. 2003;14:S227–30.
Myers RP, Fong A, Shahee AAM. Utilization rates, complications and costs of percutaneous liver biopsy: a population-based study including 4275 biopsies. Liver Int. 2008;28:705–12.
Al Knawy B, Shiffman M. Percutaneous liver biopsy in clinical practice. Liver Int. 2007;27:1166–73.
Caturelli E, Giacobbe A, Facciorusso D, et al. Percutaneous biopsy in diffuse liver disease: increasing diagnostic yield and decreasing complication rate by routine ultrasound assessment of puncture site. Am J Gastroenterol. 1996;91:1318–21.
Luning M, Schroder K, Woldd H, et al. Percutaneous biopsy of the liver. Cardiovasc Intervent Radiol. 1991;14:40–2.
Yavuz K, Geyik S, Petersen B, Lakin P, Keller FS, Kaufman JA. Transjugular liver biopsy via the left jugular vein. J Vasc Interv Radiol. 2007;18:237–41.
Savader SJ, Prescott CA, Lund GB, Osterman FA. Intraductal biliary biopsy: comparison of three techniques. J Vasc Interv Radiol. 1996;7:743–50.
Savader SJ, Lynch FC, Radvany MG, et al. Single-specimen bile cytology: a prospective study of 80 patients with obstructive jaundice. J Vasc Interv Radiol. 1998;9:817–21.
Harell GS, Anderson MF, Berry PF. Cytologic bile examination in the diagnosis of biliary duct strictures. Am J Roentgenol. 1981;137:1123–6.
Muro A, Mueller PR, Ferrucci Jr JT, Taft PD. Bile cytology: a routine addition to percutaneous biliary drainage. Radiology. 1983;149:846–7.
Lee MJ. Biliary intervention. In: Kaufman JA, Lee MJ, editors. Vascular and interventional radiology: the requisites. Philadelphia: Mosby; 2004. p. 558–87.
Jung GS, Huh JD, Lee SU, Han BH, Chang HK, Cho YD. Bile duct: analysis of percutaneous transluminal forceps biopsy in 130 patients suspected of having malignant biliary obstruction. Radiology. 2002;224:725–30.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this chapter
Cite this chapter
Thabet, A., Gervais, D.A. (2014). Liver Biopsy. In: Ahrar, K., Gupta, S. (eds) Percutaneous Image-Guided Biopsy. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8217-8_13
Download citation
DOI: https://doi.org/10.1007/978-1-4614-8217-8_13
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-8216-1
Online ISBN: 978-1-4614-8217-8
eBook Packages: MedicineMedicine (R0)