Abstract
Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory disease of medium-sized arteries characterized by abnormal cell growth leading to stenosis, occlusion, dissection, or aneurysm formation. It was first described in a 5-year-old child by Leadbetter in 1938; however, the first accurate pathologic description was set by McCormack and coworkers in 1958. Almost every artery can be involved, and in 26 % of patients, more than one arterial region is involved. It involves the renal arteries in 60–75 % of cases and is often bilateral, cerebrovascular arteries in 25–30 %, visceral arteries in 9 %, and less commonly in the carotid, iliac, or other vessels. The incidence of FMD is unknown; however, it is more common than previously thought.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Olin JW, Froehlich J, Gu X, et al. The United States registry for fibromuscular dysplasia: results in the first 447 patients. Circulation. 2012;125(25):3182–90.
Leadbetter WF, Burkland CE. Hypertension in unilateral renal disease. J Urol. 1938;39:611–26.
McCormack IJ, Hazard JB, Poutasse EF. Obstructive lesions of the renal artery associated with remediable hypertension. Am J Pathol. 1958;34:582 (abstract).
De Bray JM, Marc G, Pautot V, Vielle B, Pasco A, Lhoste P. Fibromuscular dysplasia may herald symptomatic recurrence of cervical artery dissection. Cerebrovasc Dis. 2007;23(5–6):448–52.
Luscher TF, Lie JT, Stanson AW, et al. Arterial fibromuscular dysplasia. Mayo Clin Proc. 1987;62(10):931–52.
Olin JW, Sealove BA. Diagnosis, management, and future developments of fibromuscular dysplasia. J Vasc Surg. 2011;53(3):826–36. e1.
Poloskey SL, Olin JW, Mace P, Gornik HL. Fibromuscular dysplasia. Circulation. 2012;125:e636–9.
Slovut DP, Olin JW. Fibromuscular dysplasia. N Engl J Med. 2004;350:1862–71.
Begelman SM, Olin JW. Fibromuscular dysplasia. Curr Opin Rheumatol. 2000;12:41–7.
Kincaid OW, Davis GD, Hallermann FJ, Hunt JC. Fibromuscular dysplasia of renal the arteries: arteriographic features, classification, and observations on natural history of disease. Am J Roentgenol Radium Ther Nucl Med. 1968;104:271–82.
Schreiber MJ, Pohl MA, Novick AC. The natural history of atherosclerotic and fibrous renal artery disease. Urol Clin North Am. 1984;11:383–92.
Goncharenko V, Gerlock Jr AJ, Shafff MI, Hollifield JW. Progression of renal artery fibromuscular dysplasia in 42 patients as seen on angiography. Radiology. 1981;139:45–51.
Colyer Jr WR, Cooper CJ. Management of renal artery stenosis: 2010. Curr Treat Options Cardiovasc Med. 2011;13(2):103–13.
Carman TL, Olin JW, Czum J. Noninvasive imaging of renal arteries. Urol Clin North Am. 2001;28:815–26.
Zeller T, Rastan A, Noory E. Renal artery intervention – endovascular technique. Vasc Dis Manag. 2011;8:E21–7.
Prasad A, Zafar N, Mahmud E. Assessment of renal artery fibromuscular dysplasia: angiography, intravascular ultrasound (with virtual histology), and pressure wire measurements. Catheter Cardiovasc Interv. 2009;74:260–4.
Feldman RL, Wargovich TJ, Bittl JA. No-touch technique for reducing aortic wall trauma during renal artery stenting. Catheter Cardiovasc Interv. 1999;46:245–8.
Cluzel P, Raynaud A, Beyssen B, Pagny JY, Gaux JC. Stenoses of renal branch arteries in fibromuscular dysplasia: results of percutaneous transluminal angioplasty. Radiology. 1994;193:227–32.
Birrer M, Do DD, Mahler F, Triller J, Baumgartner I. Treatment of renal artery fibromuscular dysplasia with balloon angioplasty: a prospective follow-up study. Eur J Vasc Endovasc Surg. 2002;23:146–52.
Gowda MS, Loeb AL, Crouse IJ, Kramer PH. Complementary roles of color flow duplex imaging and intravascular ultrasound in the diagnosis of renal artery fibromuscular dysplasia: should renal angiography serve as gold standard? J Am Coll Cardiol. 2003;41:1305–11.
Airoldi F, Palatresi S, Marana I, et al. Angioplasty of atherosclerotic and fibromuscular renal artery stenosis: time course and predicting factors of the effects on renal function. Am J Hypertens. 2000;13:1210–7.
De Fraissinette B, Garcier JM, Dieu V, et al. Percutaneous transluminal angioplasty of dysplastic stenoses of the renal artery: results on 70 adults. Cardiovasc Intervent Radiol. 2003;26:46–51.
Davies MG, Saad WE, Peden EK, et al. The long term outcomes for percutaneous therapy for renal artery fibromuscular dysplasia. J Vasc Surg. 2008;48:865–71.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this chapter
Cite this chapter
Taleb, M., Cooper, C.J. (2014). Fibromuscular Dysplasia: Renal. In: Dieter, R., Dieter, Jr., R., Dieter, III, R. (eds) Endovascular Interventions. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7312-1_35
Download citation
DOI: https://doi.org/10.1007/978-1-4614-7312-1_35
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-7311-4
Online ISBN: 978-1-4614-7312-1
eBook Packages: MedicineMedicine (R0)