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Histiocytosis

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Pediatric Skin of Color

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Abstract

Histiocytosis or histiocytic disorders comprise a large and diverse group of entities that have as common denominator infiltration and/or abnormal accumulation of histiocytes within blood and other tissues. In many of these disorders, the skin plays a key role in diagnosis, and may be the only organ involved. In skin of color, histiocytic disorders can present with different characteristics and look different than in lighter skin tones. The purpose of this chapter is to review some of the histiocytic disorders that affect mainly the pediatric population and highlight differences that might be present in the different skin tones of children of color.

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Abbreviations

BCH:

Benign cephalic histiocytosis

CSHRH:

Congenital self-healing reticulohistiocytosis

GEH:

Generalized eruptive histiocytoma

HLH:

Hemophagocytic lymphohistiocytosis

ICH:

Indeterminate-cell histiocytosis

JXG:

Juvenile xanthogranuloma

LC:

Langerhans cells

LCH:

Langerhans cell histiocytosis

MPS:

Mononuclear phagocytic system

MRH:

Multicentric reticulohistiocytosis

MS:

Multisystem

PNH:

Progressive nodular histiocytosis

RDD:

Rosai–Dorfman disease

SHML:

Sinus histiocytosis with massive lymphadenopathy

SS:

Single-system

XD:

Xanthoma disseminatum

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Authors and Affiliations

  1. Dermatology Section, Department of Pediatric Medicine, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada

    Blanca Del Pozzo-Magaña M.D. & Irene Lara-Corrales M.D., M.Sc.

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  1. Blanca Del Pozzo-Magaña M.D.
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  2. Irene Lara-Corrales M.D., M.Sc.
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Correspondence to Blanca Del Pozzo-Magaña M.D. .

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Editors and Affiliations

  1. Department of Dermatology, Mt. Sinai St. Luke’s-Roosevelt Hospital and Beth Israel Medical centers, New York, New York, USA

    Nanette B. Silverberg

  2. Department of Pediatric Dermatology, National Institute of Pediatrics, Mexico City, Mexico

    Carola Durán-McKinster

  3. Department of Dermatology, Changi General Hospital, Singapore, Singapore

    Yong-Kwang Tay

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Del Pozzo-Magaña, B., Lara-Corrales, I. (2015). Histiocytosis. In: Silverberg, N., Durán-McKinster, C., Tay, YK. (eds) Pediatric Skin of Color. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6654-3_23

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  • DOI: https://doi.org/10.1007/978-1-4614-6654-3_23

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-6653-6

  • Online ISBN: 978-1-4614-6654-3

  • eBook Packages: MedicineMedicine (R0)

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