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Research on the Pathophysiology of Chiari I-Related Symptoms and Syringomyelia, with Emphasis on Dynamic MRI Techniques

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The Chiari Malformations

Abstract

The pathophysiology of Chiari-related symptoms and syringomyelia remains enigmatic. Present-day technology, most notably MR imaging, is providing progressively more sophisticated opportunities to test traditional as well as contemporary theories while adding to conventional animal models a selection of promising mechanical and computational representations of syringomyelia and its etiologies. We will briefly touch on the past and present of Chiari-related syringomyelia research with emphasis on essential questions related to the development of not just the anatomical anomalies but also the constellation of symptoms with which they are associated.

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Author information

Authors and Affiliations

  1. Department of Neurological Surgery, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, K4/822, Madison, WI, 53792, USA

    Carolina Sandoval-Garcia MD

  2. Department of Neurological Surgery, University of Wisconsin, 600 Highland Avenue, K4/832, Madison, WI, 53792, USA

    Bermans J. Iskandar MD

Authors
  1. Carolina Sandoval-Garcia MD
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  2. Bermans J. Iskandar MD
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Corresponding author

Correspondence to Bermans J. Iskandar MD .

Editor information

Editors and Affiliations

  1. Children's Hospital of Alabama, 7th Ave S 1600, Birmingham, 35233-1711, Alabama, USA

    R. Shane Tubbs

  2. The Children's Hospital of Alabama, 7th Ave S 1600, Birmingham, 35233-1711, Alabama, USA

    W. Jerry Oakes

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Sandoval-Garcia, C., Iskandar, B.J. (2013). Research on the Pathophysiology of Chiari I-Related Symptoms and Syringomyelia, with Emphasis on Dynamic MRI Techniques. In: Tubbs, R., Oakes, W. (eds) The Chiari Malformations. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6369-6_13

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  • DOI: https://doi.org/10.1007/978-1-4614-6369-6_13

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-6368-9

  • Online ISBN: 978-1-4614-6369-6

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