Skip to main content

Musculoskeletal Manifestations of SLE

  • Chapter
  • First Online:
Lupus Erythematosus

Abstract

Musculoskeletal involvement constitutes the most frequent problem seen in patients with SLE. The majority of patients will describe joint pain and achiness either at the onset of the disease or later during its course. Yet the frequency of arthralgia or arthritis in lupus populations is quiet variable; for example, in one series described by Fries, it was observed in 53 % of 193 patients, and in the Dubois series, it was described at some time during the course of the illness in 92 % of 520 patients. Although the traditional teaching considers lupus arthritis to be nondeforming and nonerosive, there are many exceptions to this rule.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Sources

  1. Fries J, Holman H. Systemic lupus erythematosus: a clinical analysis. Philadelphia: WB Saunders; 1975.

    Google Scholar 

  2. Dubois EL, Tuffanelli DL. Clinical manifestations of systemic lupus erythematosus. Computer analysis of 520 cases. JAMA. 1964;190:104–11.

    Article  PubMed  CAS  Google Scholar 

  3. Pekin TJ, Zvaifler NJ. Synovial fluid findings in systemic lupus erythematosus. Arthritis Rheum. 1970;13:777.

    Article  PubMed  Google Scholar 

  4. Osler W. On the visceral complications of erythema exudativum multiforme. Am J Med Sci. 1895;110:629–46.

    Article  Google Scholar 

  5. Zvaifler N. Chronic post-rheumatic fever (Jaccoud’s) arthritis. N Engl J Med. 1962;267:10–5.

    Article  Google Scholar 

  6. Alarcon-Segovia D, Abud-Mendoza C, Iglesias-Gamarra A. Deforming arthropathy of the hands in systemic lupus erythematosus. J Rheumatol. 1988;15:65–9.

    PubMed  CAS  Google Scholar 

  7. Weissman BN, Rappoport AS, Sosman JL, Schur PH. Radiographic findings in the hands in patients with systemic lupus erythematosus. Radiology. 1978;126:313–7.

    PubMed  CAS  Google Scholar 

  8. Potasman I, Bassan HM. Multiple tendon rupture in systemic lupus erythematosus: case report and review of the literature. Ann Rheum Dis. 1984;43(2):347–9.

    Article  PubMed  CAS  Google Scholar 

  9. Van Vugt RM, Derksen RH, Kater L, Bijlsma JW. Deforming arthropathy or lupus and rhupus hands in systemic lupus erythematosus. Ann Rheum Dis. 1998;57:540–4.

    Article  PubMed  Google Scholar 

  10. Panush RS, Edwards L, Longley S, et al. ‘Rhupus’ syndrome. Arch Intern Med. 1988;148:1633–6.

    Article  PubMed  CAS  Google Scholar 

  11. Kamran M, Wachs J, Putterman C. Necrotizing fasciitis in systemic lupus erythematosus. Semin Arthritis Rheum. 2008;37:236–42.

    Article  PubMed  Google Scholar 

  12. Gladman DD, Urowitz MB, Chaudhry-Ahluwalia V, Hallet DC, Cook RJ. Predictive factors for symptomatic osteonecrosis in patients with systemic lupus erythematosus. J Rheumatol. 2001;28:761–5.

    PubMed  CAS  Google Scholar 

  13. Prasad R, Ibanez D, Gladman D, Urowitz M. The role of non-corticosteroid related factors in osteonecrosis (ON) in systemic lupus erythematosus: a nested case-control study of inception patients. Lupus. 2007;16:157–62.

    PubMed  CAS  Google Scholar 

  14. Miyakis S, Lockshin MD, Atsumi I, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006;4:295–306.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Simon M. Helfgott M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media New York

About this chapter

Cite this chapter

Helfgott, S.M. (2012). Musculoskeletal Manifestations of SLE. In: Schur, P., Massarotti, E. (eds) Lupus Erythematosus. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1189-5_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-1189-5_7

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-1188-8

  • Online ISBN: 978-1-4614-1189-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics