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Fibrous Dysplasia

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Bone Tumors

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Abstract

Fibrous dysplasia is a benign  deforming lesion involving one or several bones in which the structure of bone is replaced with altered osteofibrous tissue. It appears in a mono or polyostotic form. Treatment is based on biphosphonates and also by surgery when deformed bones occur.

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References

  1. Pitcher JD, Weber KL. Benign fibrous and histiocytic lesions. In: Schwartz HS, editor. Orthopedic knowledge update musculoskeletal tumors. 2nd ed. Rosemont, IL: American Academy of Orthopedic Surgeons; 2007. p. 121–32.

    Google Scholar 

  2. Fibrous dysplasia. In: Campanacci M, Bertoni F, Bacchini P, Enneking W, Notini S, editors. Bone and soft tissue tumors. New York: Springer-Verlag;1990. p. 391–418.

    Google Scholar 

  3. Hillock R, Zuppan C. Fibrous dysplasia. Orthop Knowl. 2007; 5(4).

    Google Scholar 

  4. Ruggieri P, Sim FH, Bond JR, Unni KK. Malignancies in fibrous dysplasia. Cancer. 1994;73(5):1411–24.

    Article  CAS  Google Scholar 

  5. Chapurlat RD, Hugueny P, Delmas PD, Meunier PJ. Treatment of fibrous dysplasia of bone with intravenous pamidronate: Long-term effectiveness and evaluation of predictors of response to treatment. Bone. 2004;35(1):235–42.

    Article  CAS  Google Scholar 

  6. Guille JT, Kumar SJ, MacEwen GD. Fibrous dysplasia of the proximal part of the femur: Long-term results of curettage and bone-grafting and mechanical realignment. J Bone Joint Surg Am. 1998;80(5):648–58.

    Article  CAS  Google Scholar 

  7. Lane JM, Khan SN, O’Connor WJ, et al. Bisphosphonate therapy in fibrous dysplasia. Clin Orthop Relat Res. 2001;382:6–12.

    Article  Google Scholar 

  8. Ozaki T, Hamada M, Sugihara S, Kunisada T, Mitani S, Inoue H. Treatment outcome of osteofibrous dysplasia. J Pediatr Orthop B. 1998;7(3):199–202.

    Article  CAS  Google Scholar 

  9. Boyce AM, Chong WH, Yao J, et al. Denosumab treatment for fibrous dysplasia. J Bone Miner Res. 2012;27(7):1462–70.

    Article  CAS  Google Scholar 

  10. DiMeglio LA. Bisphosphonate therapy for fibrous dysplasia. Pediatr Endocrinol Rev. 2007;4(Suppl 4):440–5.

    PubMed  Google Scholar 

  11. Mansoori LS, Catel CP, Rothman MS. Bisphosphonate treatment in polyostotic fibrous dysplasia of the cranium: Case report and literature review. Endocr Pract. 2010;16(5):851–4.

    Article  Google Scholar 

  12. Most MJ, Sim FH, Inwards CY. Osteofibrous dysplasia and adamantinoma. J Am Acad Orthop Surg. 2010; 18(6):358–366.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Pontificia Universidad Católica de Chile, Santiago, Chile

    Jaime Paulos

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  1. Jaime Paulos
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Correspondence to Jaime Paulos .

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Editors and Affiliations

  1. Pontifical Catholic University of Chile, Santiago, Chile

    Jaime Paulos

  2. Unité d'Orthopédie, CHU de Marseille Hôpital Nord, Marseille, France

    Dominique G. Poitout

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Paulos, J. (2021). Fibrous Dysplasia. In: Paulos, J., Poitout, D.G. (eds) Bone Tumors. Springer, London. https://doi.org/10.1007/978-1-4471-7501-8_20

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  • DOI: https://doi.org/10.1007/978-1-4471-7501-8_20

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-7499-8

  • Online ISBN: 978-1-4471-7501-8

  • eBook Packages: MedicineMedicine (R0)

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